Megan Donner returns to the CSI unit in time to work on a jet crash in the Everglades. While searching for survivors, they inexplicably discover a female victim found five miles from the crash site. When the only survivor says the woman opened the plane's hatch in order to commit suicide, Horatio is suspicious. The team must now recreate what happened on that fatal flight, especially when the pieces don't quite fit together.
A dead man with a slit throat and a partially burned face is discovered on a Miami beach, along with an unconscious young girl who was beaten and thrown into the ocean. The investigation leads Horatio to a prominent Florida family and its steely patriarch, who was once involved in a mysterious case that has plagued Horatio for years.
The whole team investigates the crime scene of an indoor amusement park when a young girl is found dead in the bathroom. They must track down the relentless man responsible for the heinous crime quicker than usual, as everyone on location has been detained until they can be cleared. What looks to be like a regular attempted kidnapping turns out to be much more than any of the detectives had bargained for.
Horatio and his team must uncover the evidence in the brutal murder of an entire family in their own home. The only survivors are a blood-soaked toddler, and the father who's in surgery. The immediate assumption is that the mother is responsible – post-partum depression – but the evidence discloses a different outcome.
During a typical morning rush hour in downtown Miami, an unseen sniper chooses three victims at random and opens fire, killing each with a single shot to the head. Horatio and his crew rush to the scene, which is quickly mobbed by TV news reporters eager to spin the murders into a national story. The initial investigation doesn't reveal much, as there were no witnesses and little evidence remains. But the case heats up when the sniper strikes again, killing two more innocent people.
Horatio and Speedle investigate the slaying of a hooker who is found dead under a bed in a plush beachside cottage, her naked body having been stabbed 23 times. But the crime scene yields few traces of blood because the killer bathed the victim in the cottage's tub with cardamom soap. Across town at an urban gas station, Calleigh and Delko attempt to uncover why a German tourist was gunned down in an apparent carjacking. They learn that a masked assailant approached a vacationing couple's rental car, shot and killed the husband, but left the wife unharmed and then fled the scene.
A dead junkie is found on a Miami street with a broken neck and a wad of cash in his hand. When the body is taken to the lab, Alexx notices that the victim's right hand is burned down to the muscle, even though it wasn't like that when he was found. It's deduced that he was exposed to radioactive material. The investigation leads Horatio to an environmental lawyer involved in radiation cases. Shortly thereafter, she learns that she is being eaten up inside by the deadly substance and has only days to live, but she doesn't know how she ingested it or who gave it to her.
Shortly before Horatio is set to testify at a high-profile murder case in which the defendant is the husband of a city councilwoman, he's given new facts that could prove the man is innocent. The information revolves around the discovery of a second victim who matches the profile of the first one and was killed in a similar manner. If the man on trial isn't guilty, then Horatio fears that a serial killer may be on the loose.
The investigation into a drug heist offers brief glimpses into the private lives of the CSIs, whose nerves are on edge when they become suspects in the crime they're trying to solve. A police convoy headed across town includes an unmarked truck filled with confiscated drugs being taken to an incinerator to be destroyed. The trip ends abruptly when thieves hijack the vehicle, kill its driver and shoot Speedle, who was riding shotgun. It's hard for Horatio when the media draw comparisons to a similar case several years ago in which his brother, an undercover cop, was killed. But it's worse for his team when Internal Affairs decides that one of them tipped off the robbers about the delivery.
Horatio battles the FBI and U.S. Marshals as he tries to uncover why a woman was murdered at the side of a pool at a hotel. The investigation begins shortly after the woman is found dead from two shots to the head. The evidence suggests that it was a professional hit man, which is strange enough, but the case becomes additionally puzzling when the Feds and U.S. Marshals get involved. Plus, the murder weapon is linked to a cold case that was orinially investigated by Yelina. Meanwhile, Calleigh talks to her dad about his drinking problem after she's called away from work to drag him out of a bar.
Horatio is approached by a parolee he helped put away several years ago, who begs for his assistance in finding his missing teenage son. As the investigation gets underway, Horatio discovers that the boy may be planning a deadly assault at his high school. Meanwhile, as Speedle investigates a man's death, the victim's flirtatious girlfriend, who was there when he died, tries to play on Speedle's obvious attraction to her.
The team investigates the deaths of two college students who were in Miami on spring break. The first is a teenage girl found dead on a beach with her neck broken and human bite marks on her legs. The second is a young man found in the bottom of a hotel swimming pool who apparently died before he hit the water.
Speedle and Delko are present when a trendy nightclub catches fire, apparently from a DJ's pyrotechnics display, killing sixteen people and injuring dozens of others. But the ensuing investigation reveals it may have been arson to cover up a murder. Meanwhile, Horatio probes the death of a prostitute whose body is found in the bathroom of a judge's home and evidence suggests that she was in the club during the fire.
An explosion in a rundown barn nearly kills Horatio and his crew just after they find a dead man inside, bound with duct tape. The case gets personal for Horatio when he discovers that the leading suspect knew his late brother. Meanwhile, Alexx is shocked to learn that her best friend's husband has been murdered, apparently the victim of a random shooting.
An inmate at a massive Miami prison complex is stabbed to death in the prison yard. Shortly after Horatio arrives on the scene, a helicopter appears above the correctional facility. He immediately fears that the murder was a decoy to set up an escape. That's confirmed as three prisoners hop aboard the chopper and flee. As the investigation gets underway, the identities of the fugitives become known and a horrible realization sweeps over Horatio: two of the escapees are cold-blooded killers who already have their next victims picked out, and the other is a child molester who he recently put away.
The two young owners of a city bar are gunned down after hours and another man is wounded in the attack, which was allegedly committed by a masked gunman. Meanwhile, Calleigh's dad announces he is now a public defender and needs her help with a murder case in which a woman allegedly stabbed her boyfriend to death in his car with a screwdriver.
A man and his wife are trying to drive out of a hurricane's fury when they strike and kill a man in the blinding storm. Horatio finds that the lack of impact wounds on the victim's knees suggest that he struck the car as opposed to the car striking him. Meanwhile, in a seemingly unrelated case, Horatio finds another victim of the hurricane impaled on a fence. However, as the CSIs uncover the scattered remains of the post-storm evidence, it seems that these two cases may have a deadly connection. Meanwhile, after Calleigh witnesses a man looting a house, she realizes that she's got another case on her hands when she finds his ex-wife inside shot to death.
A young woman is attacked by a shark and later dies, but it's discovered that she was shot first. The case becomes even more difficult for the CSIs when one of their coworkers becomes a leading suspect. The dead woman worked for a private-investigation agency that specializes in luring and entrapping married men suspected of infidelity.
A young woman is thrown over the railing of a parking garage, but the investigation into her death uncovers evidence that she was killed before the fall and had likely been kidnapped. The victim's watch is traced to her boyfriend, who tells the detectives that she was a thrill seeker who was abducted during the course of an extreme kind of role-playing game. Meanwhile, Delko gets into trouble when he inadvertently interferes with a case after stumbling across a car-theft ring.
An anesthesiologist who worked in a beauty clinic is discovered swinging from a rope in his two-story condo, but the investigation points to murder, not suicide. The case intensifies when it's learned that the doctor lost a patient the week before during routine plastic surgery and that the victim's husband believes she was killed.
A diamond broker carrying two million dollars in merchandise is murdered after his car is hit by another vehicle and he gets out to confront the driver. The only witness to the crime is a developmentally challenged man who says the killer is someone named Colton. Meanwhile, outside of town, Speedle and Delko investigate the death of a teenage girl discovered at a rest stop with a broken neck. Shortly after the victim is taken from the scene, her body disappears during transport to Miami.
A cigarmaker is found in his store tied up, beaten, mutilated, and murdered with a chaveta, a cigar-making tool featuring a rounded blade. The investigation leads Horatio to a group that helps Cuban refugees. Across town, a 25-year-old man is gunned down while withdrawing money from an ATM, but the motive doesn't appear to be robbery since the cash he withdrew is left behind.
Delko and Alexx are nearly burned alive when they investigate the death of a hunter found shot near a supposedly controlled burn in the Everglades. The fire suddenly rages out of control and traps them, forcing them to take refuge under a tarpaulin. Later, a second body is discovered, and this time it's a young woman who looks to have been beaten to death. After bite marks are found on the victim's breasts, Horatio is led to believe a sex offender is behind the attack – and the fire.
When a former surf champion is murdered in his home, the CSIs are determined to find the killer. Ted Henderson is killed in his own home and his body is missing, while his wife and son are left beaten and bound. While searching the home, Horatio finds heroin in the son's room and learns that he is secretly a drug dealer. Meanwhile, the CSIs find a home pregnancy kit in the bathroom that reveals Ted's wife is pregnant, but Alexx finds proof that the baby could not possibly be Ted's. Now, Horatio and the team find evidence that suggests that someone at Ted's surfboard manufacturing plant was not only the son's supplier, but may have a strong motive for the murder as well.
Horatio is quick on the scene when an armored truck carrying $3.2 million is robbed in a daring downtown heist. During the holdup, the driver is killed and Horatio guns down one of the two thieves. The other escapes with the loot, but the money turns out to be counterfeit. The team must figure out what happened to the bank's money before it was replaced with fake bills. Making the day even worse for Horatio, Yelina spies him with his niece and assumes the girl is his illegitimate child, not her own late husband's daughter.
Horatio and Speedle's case hinges on the testimony of a forensic-evidence enthusiast who stole a blood-drenched latex glove from the scene of the murder of a man who was stabbed to death with a butterfly knife. When Speedle tracks him down, the CSI wannabe is impressed by the ease with which Speedle was able to locate him, and the two begin to develop a slight bond when he shows up at the crime lab the night before he is set to testify. However, their relationship is cut short when the young man is found dead in his forensics-shrine of a home. Meanwhile, Delko and Calleigh probe the shooting death of a young woman whose body is found wrapped in a plastic garbage bag in a dumpster near the ritzy Miami club where she worked.
Josh Dalton, a hot, young reporter for the Miami Sun, witnesses the murder of his friend, a city councilman's aide, in Miami's drug district, the Golden Triangle. Josh, who was suspiciously unharmed in the attack, claims that they were only down there on a story, but Horatio believes that there's more to the situation. Later, another writer from the same paper is found shot to death inside the trunk of her car, which was reported stolen. Now, as the evidence rejects Josh's version of what happened, the CSIs find themselves entangled in the world of fast-paced journalism and learn that there is a dangerously fine line between the truth and what sells newspapers.
A police officer collapses and dies after pulling over a car, and the investigation reveals he was murdered. Horatio grows suspicious when Internal Affairs gets involved in the case, leading him to believe that the killing wasn't a random crime. Meanwhile, Calleigh aids an abused woman who is living with one of the suspects in the probe. Yelina begins dating Horatio's nemesis – who is heading up the Internal Affairs inquiry.
After a small plane crashes at a Miami beach and the pilot dies, Horatio finds remnants at the crash site of chemical used in making cocaine, and it seems that the victim's business partner may have sabotaged the aircraft. However, when evidence suggests that the pilot may have died before the crash, the team investigates the victim's neighbors – all wealthy residents of a secluded cul-de-sac where lust, jealousy and greed are dangerous motives for murder.
A security guard is found dead after shots ring out at a rap star's concert and the CSIs must investigate. Rap star 10-Large won't talk to the police regarding the murder or why someone would try to kill him. But when evidence suggests that perhaps 10-Large's bodyguard was the intended target, the CSIs must look into the dangerous world of personal security. Meanwhile, Alexx gets the shock of her life when a supposed cadaver from a recent car accident wakes up in her morgue, suffering only from hypothermia.
When a teenage girl returns home from a big party night at an underage nightclub to find her parents murdered, the search for the killer leads Horatio to New York City. Before he arrives, the New York detectives, led by Detective Mac Taylor, are called out to investigate the shooting of an undercover police officer – who, it turns out, is the lead suspect in the Miami case. However, the medical examiner determines that he has been dead for 72 hours and could not even have been alive at the time of the double-murder in Miami. After further investigation, Horatio and Mac determine that the real killer murdered the New York cop, then used his ID to get to Miami, and is still on the loose.
An adult film actress is found strangled in the park and the CSIs must find the killer. Blood and human tissue are found under Ashley Anders' nails and the DNA matches that of the CEO of the company that distributes her films – and he's a registered sex offender. Also, Calleigh discovers his answering machine audiotape on which he makes a threat against Ashley. However, there is an accident back at the lab with this crucial piece of evidence and Delko was the last person to handle it. Now, IAB's Rick Stetler is put on the case, much to Horatio's dismay, as the CSIs try to uncover further evidence in order to find the girl's killer.
After a large yacht slams into a major Miami bridge, the team finds that the man steering the boat was shot and killed before the accident. The victim's wife reveals that their son had been kidnapped and her husband was handing over the ransom – three million dollars worth of jewels. But when the team learns that the jewels were fake, the investigation leads them into a dangerous situation at a jewelry shop that may contain crucial evidence, where Horatio must face the unimaginable when one of the team is killed in the line of duty.
A woman is killed during a posh party at an exclusive waterfront estate when a man opens fire on the proceedings from a cigarette boat. When a former con is arrested, he acts as his own lawyer and proves to be smarted than he appears. Complicating matters is the fact that the leading witness in the case is the dead woman's 10-year-old son, whom Horatio wants to protect, refusing to let him testify.
The CSIs must find the killer after a young woman is pushed in front of a moving bus. Alexx finds a bruise shaped like a hand imprint on the victim's back, proving that she was pushed in front of the bus, and her boyfriend, Jay Seaver, is the prime suspect. When one of Jay's office rivals also turns up dead, Jay reveals that he has a psychotic stalker, Claudia, who he thinks might kill to please him. However, when Jay hires a lawyer to protect Claudia, Horatio suspects that Jay may be more involved than they thought. Later, a man's body is discovered down an elevator shaft in a nearby building, and there is evidence to link the victims to a common killer. Meanwhile, Calleigh's father seeks her help when he fears that he may have killed someone after a night of drinking, and Horatio assigns a new CSI, Ryan Wolfe, to the case.
E-mails and text messages trigger a mass gathering of students to perform a random task on a golf course. However, as the crowd disperses, the body of a high school student is found. The original message triggering the "flash mob" is traced to a high school senior whose father is a high-powered defense attorney. The case changes direction when Horatio and the team learn that the schoolmaster's daughter may have had something to do with the murder and evidence reveals that the victim was having an affair with his chemistry teacher.
An 18-year-old girl is stabbed to death in a bathroom of a popular Miami nightclub. Horatio learns that the victim was an investigative aide working for Alcohol Beverage Control and was monitoring underage drinking. As Horatio interviews the club's owner, an unknown man drives by the club, sees that the police are there, and crashes his car while fleeing the scene. However, the case gets more complicated when they discover another murdered victim inside the car. DNA from the second victim's watch ultimately leads them to a day spa where the services may not be entirely legal. Meanwhile, Calleigh and Ryan work together to determine whether an insecure and underage teenager at the club that night had anything to do with the murder.
The wife of a famous baseball player is brutally killed in her home and her philandering husband is charged with the crime. The jury on the case, as well as the accused and his defense, visits the house to examine the crime scene, but when the lights are dimmed, as they were when the victim was killed, and then turned back on, the ball player is found dead with a meat clever in his back and a note that reads "guilty." Now, as Horatio and the team find that the husband's defense team tampered with the crime scene, they must examine the evidence to find the couple's killers. Meanwhile, Horatio gets a call from Yelina, who tells him that her son, Ray, Jr., is missing.
As a huge tsunami heads directly towards Miami, a ten-hour warning gives citizens just enough time to evacuate the city. In the chaos, two people are killed in a parking lot and the evidence leads Horatio to discover a plot to rob a bank timed to take advantage of the evacuation. However, as the CSIs close in on the robbery already in progress, they find that it's a more elaborate crime than they previously thought. In the wake of the storm, Ryan and Alexx discover a body washed up from a local cemetery that may have a different cause of death than originally recorded. Meanwhile, Horatio suspects that Yelina is being physically abused by her boyfriend, IAB's Rick Stetler.
A murder investigation takes Horatio and the team into the world of speed dating. Richard Laken is found killed by a tire iron outside a lounge following an evening of speed-dating. The team discovers his car is covered with acetone, which traces back to one of the female guests. She reveals that she dated Laken and he dumped her, so she doused his car with nail polish remover for revenge, but she didn't kill him. Now, when Horatio and the team learn that Laken recently witnessed a serious assault at a Miami Heat basketball game, they are on the hunt for two perps instead of one.
The team investigates a modern-day piracy off the coast of Miami after six bodies are discovered floating in the ocean tied together by rope. Horatio suspects that a ship was hijacked with some of the crew killed and then dumped overboard. Evidence suggests that other crew members might have escaped on a life raft. Using radar and GPS technology, the CSIs find survivors but their stories don't match. Now, Horatio and the team must learn what really happened out in the ocean as they find themselves investigating the seamy underbelly of Miami's militias and arms dealers.
The CSIs must investigate when a pedestrian is killed after a man falls from a building and lands on him. Horatio and the team find that the victim found on the sidewalk is not the same man who fell from the building, but the unfortunate person he landed on. The CSIs discover that the fallen victim is in possession of a sex DVD involving a top Miami criminal judge and a woman with a sordid sex life. When the woman is found dead, the team must delve into the complicated personal lives of those in Miami's judicial system in order to find the killer.
When a woman is killed in what looks like a carjacking, the CSIs talk to her husband, the oldest of the three brothers who run their lucrative family business. However, when it is revealed that the victim had a gambling addiction that could have bankrupted the company, the team must follow the evidence to find the killer. Meanwhile, Alexx hires a recovering alcoholic as a body hauler and must investigate when he is accused of stealing from the dead.
When gang-related gunplay goes down in an emergency room, Horatio and the team must find the gang members responsible. The evidence suggests that an orderly in the hospital recognized the wounded gang member, who possibly killed one of the orderly's friends and alerted gang members to his location. However, the evidence doesn't match up and the CSIs discover that a cheating girlfriend, not gang retaliation, may be behind the shooting. Meanwhile, Ryan questions a mother in the emergency room after her story regarding her child doesn't add up.
During a routine traffic stop, a police officer is murdered and now Horatio and the team must track down the killer. The only witness to the murder is a civilian who was doing a ride-along with the officer, but who is now missing. Roadside evidence leads the CSIs to Missy Marshall, a teenage girl who was with the killer at the time of the murder. However, as the team searches for the civilian and the killer, they find that Missy may have been more involved with killer and the shooting than she is admitting. Meanwhile, Horatio and Rebecca's relationship is in jeopardy when they don't see eye to eye on a case.
The CSIs uncover a complex counterfeiting operation after a bellboy is found murdered at one of Miami's hottest hotels. The luggage that the deceased bellboy had been loading, as well as a heist of a special paper that money is printed on, leads the CSIs to uncover a complex counterfeiting operation. It's cruise season in Miami, which means that the population of Miami swells, giving the team even more suspects to the murder. Meanwhile, Calleigh must investigate when a woman goes missing, and is later found dead, after she and her husband attend a hot and flirty "friction" party.
When the CSIs find a woman swallowed whole and killed by a gigantic snake, they uncover a covert drug smuggling operation. Evidence leads Horatio and the team to a drug smuggling operation where large snakes are suspected of be being used to bring illegal drugs into the country to avoid detection by customs. However, when Horatio finds that Clavo Cruz, a nemesis of Horatio's who hides behind his diplomatic immunity, may be behind the operation, the team must find a legal way to put the criminal behind bars. Meanwhile, Wolfe must find the truth when two women each claim that they are the real victim of identity theft and the other is the culprit.
Evidence leads the CSIs to believe that someone started a massive fire in the Everglades in order to cover up a murder. Local prisoners are brought in as free manpower to help fight the wild fire in the Everglades. However, when a serial killer escapes the scene, Horatio must track him down before he strikes again. Meanwhile, the body of a local college student is found shot to death and the fire has destroyed the crime scene and the evidence. However, when the team uncovers an illegal moonshine operation and homemade ammunitions in the vicinity, the CSIs uncover the real reason why the boy was out there.
Someone uses a laser light to blind a pilot and bring down a jet, which carries $1.2 billion in checks to be delivered to banks on the eastern seaboard. The crime scene evidence reveals a victim, a young fundraising socialite, who was inside the plane but killed prior to the crash. Now, although the team has little to work with since the victim's wealthy family is opposing an autopsy, Horatio must follow the money trail. Meanwhile, Calleigh works on the case with her ex-boyfriend, Detective Hagen, and their romantic history could cause problems for both of them.
An extreme skateboarder and videogame tester is found dead on a half-pipe platform used to program extreme skateboarding video games. The CSIs discover that he was wearing reflective sensors when he was killed, so the motion-capture device used to produce these videogames recorded the murder as it happened, but not the murderer. Now the team delves into the highly competitive world of videogame programmers and testers to find the killer.
Horatio's life is changed forever when he learns important information about his deceased brother. Horatio must now figure out what to do with this information about his brother, Raymond, and whether or not to tell Yelina. Meanwhile, the team investigates when a woman is murdered at a crowded bar after she's approached by a female employee of a service that helps men pick-up women. Also, when Delko loses his badge after some reckless behavior and it's used in a crime, he must locate the badge before it's used again.
After a bitter custody battle, shots are fired outside the courthouse. Bullets fly and the target is the little girl's mother. Horatio goes after the father, who he suspects may not be the girl's biological father after all. However, when the mother's shady past is uncovered, the team finds that she has a lot of enemies who would like to take a shot at her. Meanwhile, Calleigh's father returns to the crime lab for her guidance but for an unexpected reason.
A former high school football star is murdered at a reunion, the CSIs must find the killer. The victim was the big man on campus in high school and there are a lot of guests at the reunion with reasons to resent him all these years. Now, the team must investigate everyone, from the head cheerleader to the school misfit, to see who held a decade-old grudge big enough to kill. Meanwhile, Horatio and Delko arrive at a crime scene and discover that it's already been processed, leading Horatio to uncover further information about his brother possibly being alive.
An axe murderer on death row is given a stay of execution just moments before it was to take place, on the grounds that there may have been tainted DNA analysis used at his trial. Now, without using any DNA evidence, the team must race against time and reexamine all of the physical evidence in the case, just as they get a call on a new double murder that looks suspiciously like the case they're working on.
While investigating the murder of man hired to make dirty bombs that terrorists intend to set off in Miami, Horatio finds the bloody fingerprint of his brother, Raymond, who he believed to be dead. However, when Raymond's son is kidnapped, he emerges from deep undercover and the estranged brothers must work together to save the boy. Meanwhile, while processing a crime scene, an unknown assailant holds a gun to Calleigh's head and, after a deadly confrontation in her gun lab, she is left doubting that she can continue as a CSI.
Three suburban housewives on a girls' weekend in Miami are the prime suspects when the hotel's handsome pool boy is found murdered. When Horatio is tipped off that his team is facing a surprise efficiency review, he must trust Calleigh, Delko and Ryan to work together to find the killer. However, when they independently follow the evidence, each discovers that their analysis points to a different killer.
The CSIs must race against time when all evidence in a murder case points to Horatio. When a murdered woman is discovered, Horatio admits that he was seeing her and that he was the last person to see her alive. Although the evidence logically points to Horatio as the killer, our CSIs must now dig deeper to find the real killer and learn who would have the motive and the method to frame him.
(Crossover episode with CSI: New York, Season 2 Episode 7.) A crossover episode that concludes on "CSI NY" begins with a convicted serial killer who escapes after sabotaging an airplane that was flying him from New York to Miami, where he allegedly buried a body. After fleeing the crash site, the man goes on a killing spree and abducts a college student. Mac Tayor arrives to help Horatio track the killer since Mac originally arrested the man in New York.
The CSI's are called out to investigate the murder of a young woman who was about to sign her divorce papers. Soon the husband turns out to be the ideal suspect. The only strange thing about the case is the murder weapon: a nailgun. The case becomes complicated when one of the CSI's is attacked when he returns to the crime scene and ends up in hospital.
Eric Delko is at the bank, following an ATM taking his debit card, when three robbers wearing ski masks rush in. Delko knows he can’t win against the three robbers but when one of them tries to rape a girl it ends in a shootout. The security tape leads them to Miami University and to the robbers next target and Horatio manages to arrest one of them. The trail leads to a videogame named “Urban Hellraisers” and when Ryan Wolfe starts playing it, it turns the similarities between the game and the actual crimes are very big. It’s up to the team to catch the robbers before they commit a crime much more serious than the last one.
A drug lord is gunned in his Coconut Grove mansion and a suspect arrested at the scene claims he sells marijuana to Delko. Stetler, from Internal Affairs, investigates and the case quickly gets personal when Horatio gets involved. As for the shooting, the CSIs learn that two gunmen may have been involved. Also, Calleigh makes a major decision concerning her job.
Alexx’s DNA is found throughout her neighborhood where she is suspected to be responsible for the death of a convicted child molester. The CSI team soon learns that mindset of the neighborhood could lead to any of community wanting the man gone. The team must find out who the real killer was to clear Alexx.
After a group of wealthy women are robbed at a luxury day spa, evidence leads the CSIs to believe that this is a part of a much larger car chopping scam and each of these women are being targeted for a home robbery. Matters become worse when Horatio discovers that Marisol was also at the spa during robbery and he must now protect her when her life is threatened. Meanwhile, Ryan must deal with the fallout after he freezes during a shootout.
The CSI team must locate a woman who has been kidnapped and dialed a wrong number on her cell phone. To try and find the woman the team must first figure out whom the kidnapped woman was trying to call in the first place. Marisol has a difficult decision to make and Horatio helps her. Natalia is surprised when Ryan asks for Delko's permission to take her out on a date.
A cruise ship that is docked in Miami is the scene for a double murder. The team investigates the long list of potential suspects but soon find that the list is dramatically decreased when the CSI's find a large amount of money is missing from the victim's stateroom. Horatio and Marisol's relationship evolves.
The episode picks up straight where "One of Our Own" left off. Horatio and Delko have arrived in Rio de Janeiro to hunt down Antonio Riaz, who ordered the hit on Marisol. The problem is that Horatio can't stop thinking about his late wife, and Brazilian authorities aren't being very cooperative. While there, Horatio runs into Yelina and finds out that Raymond is missing again. Ray Jr., now fourteen, teams up with Brazilian authorities and will stop at nothing to bring his father home safe, until Horatio learns the terrible truth... Raymond is already dead. Now Horatio must stop his nephew from getting himself killed trying to chase a ghost.
A murder and kidnapping becomes personal when DNA from a crime scene reveals that Natalia’s sister Anya is one of the kidnapped women they are looking for. The team finds a safe full of photos of missing women and they must find the photographer who was using his camera to lure the unsuspecting women.
A Marine recruiter is found dead on a civilian shooting range with various bullet holes in him, but there is no blood at the scene. The investigators uncover that the victim was dead before he was shot and that his body was pulled onto the range. As the case advances, Horatio determines the murder may be tied to the death of a marine in Iraq who was killed in combat. Likewise, Natalia is shocked to learn that Nick asked Valera out and that she accepted.
A truck carrying weapons that were confiscated from previous crimes are now back on the streets of Miami. An old enemy of Horatio's puts the lives of two CSI's in harms way after a confiscated missile is launched into courthouse allowing Clavo Cruz to escape during his arraignment and injuring one CSI and the fatality of another CSI.
The CSIs investigate when the parents of a baby sitter in an upscale neighborhood are murdered. As the team sorts through the neighbors' secrets and lies, they find an unexpected love triangle as a motive for murder. Meanwhile, a key piece of evidence found at the crime scene leads Horatio to expose a doctor with some dirty secrets of his own.
Evidence suggests a victim may have been set up as bait, after he's found to have been attacked and killed by a black bear. It's discovered the killer may have been trying to hide another murder - that of a high priced hooker and her bodyguard, who were part of a prostitution ring catering to elite Miami clients.
(Crossover episode with CSI: New York, Season 6 Episode 7 and CSI: Crime Scene Investigation, Season 10 Episode 7.) Horatio Caine calls Las Vegas CSI Dr. Ray Langston to come to Miami when a severed leg found in the Everglades is discovered to belong to a girl who went missing in Las Vegas a week earlier
This is actually CSI Season 2 Episode 22 but also served as the pilot episode for CSI: Miami. In this episode, Grissom and his crew handle their highest profile case to date when the city's former chief of detectives is slain execution-style in his house following a wild party. Missing from the residence are the chief's trophy wife and their 7-year-old daughter. Catherine and Warrick follow the trail to Miami, and soon enlist the help of Horatio Caine.