Stan Smith uses his CIA skills to help 13-year-old son Steve win class president and the heart of the hottest girl in class, Lisa Silver. But when being class president makes Steve mad with power, Stan must jump in to save the day. Meanwhile, Roger, the alien Stan saved from Area 51, helps 18-year-old Hayley with her school paper. In return, she hooks him up with boatloads of junk food to curb his sweet tooth. Unfortunately, some Chocodiles send him over the edge and a sugar crash prohibits him from finishing one of her papers, forcing Hayley to pick up the pieces. And Klaus, the goldfish with the brain of a German guy, pines after mother Francine. Unfortunately for Klaus, the closest he'll ever get to a date with her is the spin cycle with her sports bra.
Stan Smith is mad because after getting his wife a job (or "hobby") as a Real Estate agent, she makes more money than him. In the meantime, his daughter Hayley ran a program that helped the homeless, and Stan's son Steve had an idea to have a Bum Fight program. To get back and to try to gain more money than his wife, Stan takes Steve's idea and starts a Bum Fight Night where he takes bets and treats the homeless like wrestlers. But with the homeless petition, Stan has to end up fighting like a homeless man himself.
Hayley comes home from a Green Party rally with her hair dyed green, instigating a fight with Stan. While she's sleeping, Stan cuts her hair (for her own good, of course). After learning of what Stan did, a wigged Hayley defies her father yet again by moving into the van of her new boyfriend. When Stan cuts her off financially, she gets a job as a waitress in a strip club, which pushes Stan right off the edge. Meanwhile, Steve tries to pass Roger off as his disfigured sister in order to cop a feel with a female classmate.
When Stan forgets his anniversary, he arranges to have 20 hours of Francine's memory erased, but the CIA temp on duty accidentally erases 20 years. Francine, having reverted to her wild child days, moves into her old apartment with Hayley as a roommate, and ends up going to a festival with Hayley's boyfriend. Meanwhile, Steve asks a good-looking girl out, but needs his wingman, Roger, to "jump on a grenade" for him and date her ugly cousin.
Francine decides to throw a block party to get in touch with the neighborhood. Stan learns his new neighbors are Iranian and immediately suspects that they are terrorists. To prepare Steve for living near terrorists, Stan makes Steve join a group of scouts, who turn out to be trouble makers. Roger is convinced he possesses hidden alien powers and is determined to find out what they are.
Stan finds Deputy Director Bullock, his supervisor, starting a relationship with Hayley. However, he can't risk saying or doing anything about it because he's up for a promotion at the CIA. Meanwhile, Steve finds Dick Cheney's BlackBerry and uses the contact numbers to play pranks on political figures from around the world.
When Steve brings home a permission slip to take sex ed at school, Stan flips out and demands to teach it himself. However, after Stan unrealistically explains the birds and the bees to Steve, he gets into an accident that causes him to take matters into his own hands. Meanwhile, Roger becomes a bartender in hopes of making something of himself.
When the CIA organizes a father-son baseball game, Stan is determined to show his co-workers that his son is masculine and athletic. Unfortunately, Steve is a geek, so Stan decides to lie and ditches him. But after getting a taste of his own treatment at work, Stan turns to Steve and his sci-fi knowledge to help capture a cyber-terrorist. Meanwhile, Roger goes incognito in a desperate attempt to interact with humans.
When Stan's father passes away, Stan reveals his real father is actually Jack Smith, a super suave spy. Jack convinces Stan to quit the CIA and work with him at the Scarlet Alliance, an ultra-secret spy group. Francine is upset with Stan, who is busy training with Jack for a mission involving uranium, artwork and terrorists. But when the FBI shows up at the Smiths' house looking for an international jewel thief, Francine suspects Jack is the fake.
Stan has to throw a party for his boss and assumes his wife Francine will do all the work, but she refuses. With Stan as party planner, the event turns into a disaster. As a result, Stan's boss relocates Stan and his family to Saudi Arabia, where they quickly get a taste of life on foreign ground. As American and Arabian social norms clash, gender wars heat up.
As the Smiths continue to live in Saudi Arabia, Stan is fully enjoying the male-dominated society, while the rest of the family struggles with the different social norms. Meanwhile, Francine's musical expos on gender roles gets her into trouble, and a brush with death leads the Smiths to return to the United States.
Francine insists that Stan and Hayley spend an entire day together, after their arguments drive her crazy, so they can work out their differences about gun control. However, her plan backfires when he takes Hayley to the "National Gun Association Land," where their conflicting opinions about gun control drive them even further apart. Back home, Roger schemes to get revenge on Steve for eating one of his cookies by convincing him that he's adopted.
As Stan continues to dominate the household, Francine finds herself idolizing a group of women who seem to have it all. She tries to impress them and even lies in order to gain acceptance into their group, until she realizes they aren't as perfect as they seem. Meanwhile, loyalties are tested when Stan gets a new best friend.
After Stan and Roger have a rough day, they get into a fight that leads to a "Freaky Friday"-type switcheroo where they get a taste of life in each other's shoes. But after the excitement of a new life stales, they face each other's problems as Roger is under pressure at work and Stan yearns to be needed. The swap gets out of hand as the family starts to crumble.
After receiving a hefty bonus from work, Stan buys extravagant gadgets while Francine pleads for her dream kiosk. Upset about his lack of support, Francine opens a muffin shop without his approval and gives Stan a taste of life without a housewife. In a desperate move, Stan puts Klaus' brain back into a human body – only to discover it was a huge mistake as Klaus tries to win over Francine. Meanwhile, Steve is convinced he's a teen wolf after watching a horror film.
Because of a past incident at his own prom, where he was lured into a dance with the homecoming queen only to have a pile of pigs dropped on him, Stan wants revenge by showing off that he married a homecoming queen, Francine. A proud Stan accompanies Francine to her reunion, but when they find out that two ballots were lost and that Francine didn’t actually win the crown, Stan is devastated. Meanwhile, a dejected Steve is “saved” by a pizza delivery man with a Messianic message.
When Stan goes to Atlantic City for a bachelor party and is shunned by his so-called best friend, Roger steps in and becomes Stan's new sidekick. Their friendship goes to a whole new level, but when they return home and face Francine, Stan realizes that what happens in Atlantic City doesn't necessarily stay there. Meanwhile, Hayley and Steve team up to break up a good-looking couple.
Stan wants Steve to be popular and goes to desperate measures giving him steroids to make him bigger, better, and part of the in-crowd at school. But when the steroids have an unexpected side effect, Steve gets a lot more attention than anyone expected. Meanwhile, after Hayley makes a movie about Francine's life as a housewife, Francine is determined to start a new career as a doctor.
After Steve shows a lack of interest in Stan's job, Stan replaces him with Barry, Steve's malicious friend. Barry frames Steve to eliminate him from the household, but when Steve discovers Barry's weakness, he relies on his CIA skills to save the family. Meanwhile, Roger takes an impressive keg-stand and uses it to become a fraternity brother.
When Francine's birthday brings back haunting memories of a celebrity film moment stolen by George Clooney, Francine's new dream is to destroy the star. But when she tries to win Clooney's heart with the intention of breaking it, Stan actually falls for him and sabotages the plan. Meanwhile, back at home, Roger builds a vineyard and starts up a private sweat shop of foster children.
Stan realizes his own weight problem after he criticizes Steve about his new, overweight girlfriend, so he goes overboard with exercising, and develops anorexia. Steve realizes that his overweight girlfriend is the root of his father's problems, and he has to make a hard choice in an effort to save his father's life.
Stan has his heart set on speaking at the Republican National Convention on behalf of the Langley chapter, but when they pass him up for another candidate, he accepts the only endorsement he gets from the local chapter of Gay Republicans. While the people around him disapprove of his new lifestyle choice, Stan decides to follow his heart to speak on their behalf.
After Francine tells Stan she's looking for excitement in their marriage, Stan gets in the driver's seat and becomes involved in drag racing to spice things up. Meanwhile, Hayley breaks up with her boyfriend, Jeff, who is emotionally crushed until he joins Steve's world of online gaming. When Hayley finds out, she tries to sabotage their fun.
When Steve's new relationship with his girlfriend gives Francine empty nest syndrome, she tries to convince Stan to have another baby. Meanwhile, Roger tries to enroll in college with Haley in order to experience college life, but while Roger ends up teaching the class, Haley finds a new crush in her classmate Ethan (Elijah Woods), who turns out to be far from normal.
When Francine discovers Stan's secret, decades-old passion for competitive figure skating, she decides to be supportive and becomes his pairs partner until Stan's competitive nature gets the best of him and he ditches her for a new partner. Meanwhile, Steve's classmate Snot finds new respect among his peers when he parades his mail-order bride around the playground.
When Roger helps Steve see that his father isn't as smart as he always believed, the power-hungry pair set their sights on fame and fortune in New York City. It doesn't take long for Roger to lose everything on Wall Street, and Steve contemplates prostitution after Jon Stewart shoots down his comedy routine. Meanwhile, the rest of the family is certain that the two have just run away to the tree house, so when it explodes in a lightning storm, they are devastated, but console themselves with Steve's college fund.
When an injunction prevents Langley Falls from lighting their annual Christmas tree, Stan blames secular non-believers for ruining his favorite holiday. With Stan's holiday spirit at an all-time low, the Ghost of Christmas Past visits him and tries to show him the true meaning of Christmas. However, Stan is convinced that Christmas can be saved by changing the outcome of Vietnam, but finds that changing the past only dramatically changes the future.
When Stan enters an essay contest to have his personal hero, President Bush, come over for dinner, he is overcome with joy when the President arrives at his doorstep. However, not everyone in the Smith family shares Stan's excitement. Hayley tries to drill President Bush on the Iraq war, and Steve and Roger attempt to convince him that they've found Osama Bin Laden, but instead get him drunk. Stan tries to save the President from public humiliation, while Hayley revels in his fall from glory.
When Stan feels like he's not climbing the ladder fast enough at work, he turns to his lifelong ambition of making festive teddy bears. However, when he realizes that making a quick profit takes a lot of work, he resorts to using illegal aliens as cheap labor. Meanwhile, Hayley sees her father's new business model as an atrocity and takes matters into her own hands by calling Uncle Sam.
When Roger is rejected by Steve, who seems to be over him, Roger heads out in search of a new human companion. But when this new friend starts to abuse Roger and the relationship turns into a lot of excuses and sorry's, Steve and Hayley scheme to get Roger out of the bad relationship and back home where he belongs. Meanwhile, Stan tours the Mr. Pibb factory and meets the man himself.
While researching a paper about George Washington Carver in celebration of Black History Month, Steve uncovers a conspiracy that's been going on since the Civil War. When the curator of the Smithsonian Peanut Museum reaches out to tell Steve the truth, he's mysteriously murdered, and Steve and Stan are tracked by a secret society that will stop at nothing to keep this scandalous secret of American history.
Stan arrives late to a CIA nuclear drill and thinks it's real. He decides to move the family into the mountains to survive the apocalypse. Even though he realizes his error, he begins to enjoy the attention that he gets from the family so much that he doesn't tell them the truth. However, when the family meets a mountain man and learns the truth, Stan has some explaining to do.
Stan sets Bullock up on a date with one of Francine's friends. Fearing that Francine will be right about the outcome of the date, Stan goes to great lengths to make sure it goes well by getting everyone drunk. Unfortunately, Bullock accidentally kills the woman, to which Stan frames Francine for the murder in order to keep her from asking so many questions.
After Stan discovers that Francine has a secret sex garden, he feels like their marriage may be crumbling. Looking to rekindle their romance, Francine asks for a divorce so that Stan can experience life as a bachelor again, and both learn a valuable lesson in love. Meanwhile, addicted to an energy drink, Steve finds himself panhandling in the streets to support his new habit.
When Stan brings home CIA equipment designed to eavesdrop on conversations, he finds out that his neighbors don't think too highly of him. In retaliation, Stan has the entire neighborhood evicted so that he can live free of any criticism. However, when an unexpected friend comes to his rescue, he realizes that gossip is a two-way street.
When Francine discovers that all of their family vacations have been artificially created memories, she gets very angry and demands a real vacation. However, when the vacation seems too good to be true, Francine is convinced it's the work of the CIA and causes the family to suffer the consequences. Meanwhile, Roger attempts to become the greatest actor who ever lived.
In order to be taken more seriously and to be a somebody, Stan becomes a meter maid who seems to have all of the power. Now he's getting the best tables at restaurants, pocketing quarters from meters and impressing Francine with his prowess. But, when Turlington from Parking Internal Affairs pays him a visit, Stan realizes crime and this lifestyle don't pay. Meanwhile, Hayley poses nude for a college art class and is surprised to see Roger there.
When Francine's adopted parents stop by for an unannounced stay, Stan is furious that they refuse to assimilate to his "man of the house" ways. After he unsuccessfully tries to give them the boot, he is convinced that finding Francine's birth parents will change things. Meanwhile, Steve tries to live to the extreme in order to get to second base with the class hottie.
When Hayley decides to move to France because of imperialistic oppression, Stan will do anything to stop her including revealing the fact that she was brainwashed as a child by the CIA. Feeling desperate, Stan activates her trigger word and gains control over Hayley against the advice of his boss, Bullock. Everything is going fine until Stan remembers that if he doesn’t change Hayley back to normal, there will be deadly consequences for him. Meanwhile, Steve and Roger become private Dick Tracys.
When Francine decides to be a surrogate for her gay neighbors Terry and Greg, Stan's Republican blood boils. Although he pretends to be happy, when the baby is born, Stan kidnaps her and heads to the Nebraska boarder, where gay couples have no rights. Meanwhile Steve and Roger pull a Howard Hughes and become reclusive after they think Klaus is out to get them.
Stan and the family are characters in a James Bond style spoof. Stan must stop Tearjerker, played by Roger, a diabolical film producer who makes movies that can kill. Tearjerker's fiendish plot involves abducting celebrities from his spa and replacing them with celebrity robots that make horrible movies, all in an effort to make his masterpiece "Oscar's Gold" the best and saddest movie ever, causing millions of moviegoers to cry themselves to death.
When Stan’s mom gets dumped for the umpteenth time by a boyfriend, she comes running to Stan for support. Feeling threatened by her always-visiting mother-in-law, Francine is determined to cut Stan’s umbilical cord and figure out what keeps going wrong with the men in her life. Like a regular Cagney & Lacey, Francine and Roger go undercover to solve the case. Meanwhile, Klaus gives Steve the ick.
Stan goes in search of a former KGB agent, Sergei, and is shocked to find that the man is his new next-door neighbor and that Sergei has already turned Steve into a communist. Meanwhile, Roger and Klaus head to France for a little R&R but their trip takes a turn for the worse when Klaus gets busted for drug smuggling.
Roger begins to release photos of himself to the local media for extra cash, prompting the CIA to initiate an Alien Task Force. Through a twist of fate, Roger ends up in charge of the task force in disguise, creating tension at home as he is now Stan's boss. Meanwhile, Francine comes to grips with being left-handed and Roger frames Stan as an alien in attempt to keep his identity a secret.
Officially declared dead after an accident with a pudding truck, Stan comes back to life to realize his dream of leaving a legacy on the world and begins to excavate his home in search of Ollie North's "Contra"-band buried treasure. As the search for gold goes "North," life at home heads south as Hayley turns to body-piercing, Steve creates a robotic girlfriend and Roger files for sexual harassment.
Stan has a Spring Break-induced mid-life crisis. With Francine away visiting her parents, Roger invites Spring Breakers to party at the Smith household. But Stan nearly has a Spring Breakdown when he falls prey to booze-cruising Jessica and Steve tries to lose his virginity to the luscious Carmen Selectra.
After Stan comes home from another dangerous mission, he finds that his family has decked the halls with boughs of holly and donned themselves with gay apparel, but just not to his satisfaction. He demands a grander Christmas starting with the search of a bigger and better tree in the forest. When his family has had enough, Stan powers on by himself, finds the perfect tree and meets an untimely end. While in Limbo, he has to fight for a second chance at life and battle the forces of good and evil to save his family.
When Steve suffers indignities in school because of the back brace he must wear for his scoliosis, Stan confides in him that he wears a wig to cover his baldness. Meanwhile, Roger invites both Francine and Hayley to a posh spa even though he has only two passes, so he sneaks in Hayley in a suitcase, raising the suspicions of the house detective.
When the Smiths try to plan a family game night, Roger is full of excuses about prior commitments. However, when he is caught in a lie, the Smiths feel stabbed in the back when they realize Roger has been cheating on them with other families. Stan, Francine, Hayley and Steve go on the offensive to teach Roger a lesson about monogamy until Roger has a breakthrough about why he isn't a one family kind-of-guy.
When Langley Falls implements a ban on trans fats, Stan finds himself legally separated from his favorite foods. He sets a poor example for the rest of the family when he blatantly disregards the law by crossing county lines and using Steve as a trans-fatty food mule to satisfy his own gluttonous desires.
Steve signs Stan up for a father-son bike tournament, but the plan veers off-track when Stan admits that his father never taught him how to ride a bike. Determined to make things better, Steve helps reconcile Stan with his convict father. Meanwhile, Hayley needs internship credit for school, so Roger hires her to bartend at his makeshift bar in the attic.
Steve and the gang sabotage a stuck-up kid's bar mitzvah after he hits on Steve's girlfriend, Debbie. But when Snot gets wrongly accused of stealing the kid's bar mitzvah money, he must answer to the Rabbi and his own celebration is in jeopardy. Meanwhile, Stan and Francine pitch a cell phone idea to Verizon, but the plan gets fuzzy when they can't deliver the goods.
When Stan gets kidnapped in Colombia, Francine fears he's gone for good. Stan finally reappears unharmed, but the real trouble erupts in the Smith household when he admits that he has a plan to marry his dentist if Francine dies before him. Meanwhile, Steve and Roger play detective duo "Wheels and the Legman."
Steve joins a junior football team to make Stan proud. However, when a hyper-competitive Stan assumes the position of head coach, Steve gets kicked off the team for not being good enough. Out for revenge, Steve and Roger recruit a new team of misfits who threaten Stan's perfect season. Meanwhile, Francine and Hayley compete for a blue ribbon at the Langley County Fair.
Stan has had enough of Roger's antics! When he calls Roger out, Roger claims he has been sent to Earth to determine the fate of mankind. Stan challenges him to prove it, and is tickled pink when he learns Roger's real purpose for being on Earth. Roger struggles to get a grip on reality until a fateful turn of events helps put things in perspective.
Neighbors Terry and Greg are nervous when Terry's father, football great Tank Bates, announces that he will be coming to town for a visit. Terry is worried because his dad doesn't know he's gay, has a baby or lives with his partner. Meanwhile, Steve goes on a drunken bender and learns the meaning of the phrase beer goggles.
When Steve is selected to sing the national anthem at the Langley Falls Veterans' Day celebration, he gets some heat from Stan who doesn't think he's ready for such an undertaking. Unimpressed with Steve's vocal talents, Stan decides Steve needs to experience real war in order to sing about our country's military prowess. But things quickly go south when Roger gets involved and Steve goes bananas.
In order to get a promotion at work, Stan has to convince the dictator of Isla Island to sign a treaty. Stan meets the general and accidentally kills him and has Roger pose as the leader of the small island nation. Meanwhile, Steve and Snot become competitive to see who can get farther with the other’s mom.
Steve is left home as the family plan a trip to Boston hoping to locate a college for Hayley. When his friends arrive they convince him to break the rules, resulting in them finding the controls to a military drone in Stan's study. Meanwhile, after Stan leaves the plane to return home for his painkillers, Roger changes disguise from a little girl to a Stan constume so he can get served alcohol. When an air marshal notices that the girl is missing, he grounds the plane and investigates.
Upset that Hayley no longer wants his advice, Stan decides to prove that she is missing out on his sage counseling. After meeting a stripper on an important CIA mission, Stan takes it upon himself to improve her life and show Hayley that his advice works. But when he opens a new business, hoping to prove Hayley wrong, he finds himself dancing for cash to cover up his failures.
When the Smith family goes to church on Christmas Day, Stan is furious when he can’t get a good seat. While Francine tries to ease his frustration, a moment of divine intervention occurs. Upset that he has been left on earth with Francine during the ultimate fight between good and evil, Stan ditches his wife to get into the pearly gates of heaven, but when Francine is kidnapped, Stan fights to get her back.
After Roger and Francine are victims of a mugging, Roger joins the police academy so he can learn how to defend himself and his loved ones (including Stan and Steve), but he falls in with a corrupt cop (guest voice Cannavale) who leads him astray. Meanwhile, Hayley's new friendship threatens her long-term relationship. Chaz kidnaps and leaves Stan tied up and tape-gagged. Meanwhile, Roger kills Chaz and rescues Stan, who makes his boss happy.
Stan is ecstatic when Roger offers to help him live out his lifelong dream of opening a restaurant to rival his favorite childhood haunt - until their different visions for what the eatery should be cause havoc. Meanwhile, Steve meets Ashley, the new girl in school who invites him over while her parents are out of town.
It’s Thanksgiving in Langley Falls, and as usual, Stan invites his half-brother, Rusty, over to show off his cornucopia of wealth and good fortune. But when Stan finds out that Rusty is far wealthier than he led on, Stan tries to take from Rusty what he feels is rightfully his. Things don’t go well, and the Smith family nearly loses it all.
If there’s one thing that Stan Smith loves, it’s a good jury trial. He anxiously awaits his annual jury summons. But when Roger is the defendant in the trial where Stan is the foreman, he is finally in a position to make Roger accountable for his misdeeds. Meanwhile, Jeff and Hayley move in with the Smiths, and Francine tries to get Jeff to clean up his act.
After Roger releases lethal gas into the Smith residence, the family moves into a hotel while the fumes clear. With no housework to do, Francine finds herself with a lot of free time on her hands. After befriending the hotel concierge (guest voice Elizondo), she soon finds herself working in the construction business, but realizes that perhaps she is better suited for family life. Meanwhile, Steve travels back in time to 1981 to meet the artist who painted a portrait of his dream girl.
With a flair for the dramatic, Roger invites Stan to attend one of his acting classes. However, tempers flare when they both audition for the same role, leaving them to duke it out for top dog. Meanwhile, Steve and his friends get into a pillow fight when they try to plan the greatest slumber party ever.
After Snot professes his love for Hayley and gets shot down, Steve and Roger devise a plan to cheer him up. Roger dresses up as Steve’s cousin from New Jersey, Jenny Fromdabloc, and Snot falls hard for her. Meanwhile, Stan wants to live like a gentleman of the 1960s, complete with dark suits and dry martinis.
Roger becomes Steve's legal guardian, but gets a little overzealous in the parenting department when he gets the principal fired. After getting beat up by the other teachers at the school, Steve decides to run away. Meanwhile, Stan and Francine attempt to make waves after discovering that their vacation at the biggest water park in the world fails to get their hearts pumping.
When Stan realizes that he might never fulfill his dream of becoming a Best Man, he convinces his last single friend, Principal Lewis to marry the school’s Superintendent and to choose him as his Best Man. Stan invites Lewis’ old friend from prison to the wedding, only to discover a secret that could prevent the wedding from happening at all. Meanwhile, Roger finds the perfect pair of shorts, and an encounter with Ricky Martin makes him question his self-confidence.
When Stan runs into his former crush from CIA boot camp, his affection for her resurfaces, which drives Francine into a jealous frenzy. By including Roger in her plan for revenge, Francine accidentally leads him straight into the arms of a dangerous alien hunter. Meanwhile, Steve is struck with good luck, when he accidentally wears Hayley’s panties to school.
When Steve tries to prove himself as a macho man to Stan, he follows in Roger's footsteps and tries to change himself from the outside in with a superhero persona. Meanwhile, Francine is going through an identity crisis of her own when she receives surprising news that could change the family forever.
When Stan finally has enough money to afford a membership at the golf club he has worked at for the past thirty summers, his hard work and perseverance prove to be futile when the club gives a membership to Steve first. However, things are not all what they seem when Stan realizes who the club owner really is.
Stan joins Roger and Steve's fictional detective agency, but he ruins the fun by being extremely incompetent at his "job." Roger demands that Steve fire Stan, but Steve cannot bring himself to do it and ends up lying to Roger. Things take a turn for the worse when Stan is kidnapped, and Steve must tell Roger the truth.