Lynn Loud Sr. and Rita Loud meet the Yates Family, consisting of Jancey and Bumper Yates Sr. and their children Beatrix Yates, Belle Yates, Bumper Yates Jr., and Beau Yates. As they see that they have an impressive life, Lynn Sr. and Rita think that their children aren't doing enough to ensure their successful futures and have them do various things to make them more well-rounded like the Yates Family.
Leni has been known to ruin the surprise party of her siblings. To keep Leni from ruining the surprise birthday party for Rita, Lincoln must work to keep Leni from spoiling the birthday surprise. As Lincoln does his part of the assignment, the rest of Lincoln's sisters work to get the party ready including the part where they involved inviting people they know to the party.
On Halloween, Lincoln and Clyde plan to go to the fancy gated community of Huntington Manor at Huntington Oaks in order to get the full-sized candy bars. Meanwhile, Lucy assembles a haunted corn maze and operates it with the help of Lori, Leni, Luna, Luan, Lynn, and Rita. Also, Lola, Lana, Lisa, and Lily compete to see who will get maximum candy as a reluctant Lynn Sr. escorts them.
When Lori and Bobby attempt to have their daily conversation, a few misunderstandings lead to them having a rather awkward conversation. Because of this, the two fear that dating long distance isn't working out for them. With encouragement from their respective parents, Lori and Bobby attempt to show each other that they care for each other though various means, like signs of affection, a home video, and virtual dating, but when that ends up not working, the two decide to spend their day together, which is just as troublesome as when they were separate.
Lynn Sr. finds out that Lynn's Table has gotten a bad review on the review website Nosh from NewNosher123 and the kids find out about. To find the culprit that is in Royal Woods, Lincoln has his sisters look for suspects and interview the other restaurants that got a thumbs down. With their suspects being Principal Huggins, Mr. Grouse, Scoots, Mrs. Bernardo, and Flip, Lincoln, his sisters, and Todd plan to lure their suspects to Lynn's Table to find out who is NewNosher123.
At Royal Woods Middle School, Lincoln, Clyde, Liam, Rusty, Zach, and Stella are in need of new broadcasting equipment for the Action News. They are approached by Chandler who offers them new broadcasting equipment. In exchange, he wants them to join the Action News Team. When that happens, Chandler makes things difficult for them by wanting a bigger part in exchange for more broadcasting equipment. Now they must find a way to get Chandler off the Action News.
Lily has been having recurring nightmares and neither of them understand her descriptions. Upon getting a description of Trashy and Tentacle, Lisa invents a dream machine in order to enter Lily's dream where she brings Lincoln, Lynn, Lola, and Leni along for the ride while having them use the return button if it becomes difficult. After Lisa's Lull-a-Bot helps them into Lily's dream, Lisa, Lincoln, Lynn, Lola, and Leni search for the nightmares plaguing Lily. Meanwhile, the rest of the family work to keep Lily from waking up while everyone is in Lily's dream.
Ever since she started Fairway University, Lori has missed a lot of stuff. At the advice of a classmate, Lori heads home for the weekend to see her family. As her siblings have plans, Lori tags along to the different activities in order to get caught up with them. When the first day goes wrong, Lori gathers her siblings for different activities the next day like the minigolf course, Dairyland, and Tall Timbers Pond which goes comically awry.
The Louds travel to London when Luna receives an invitation to Mick Swagger's knighting ceremony but get caught up in a special mission when Lincoln runs into a familiar face.
The Louds journey to Naples, Italy to taste the world's best pizza, made by a secretive and legendary chef.
Lincoln and friends try to befriend new girl Kara when they learn she has access to a legendary missing comic book.
Miguel enlists Leni's help when he launches his own perfume line at Reininger's.
Dad struggles to run Lynn's Table when his brother Lance opens up a gym above the restaurant.
Privy to all the gossip at school, Lola is recruited to write her own gossip column in the school newspaper.
To commemorate their video hitting 10,000 streams, the Moon Goats agree to all get matching tattoos.
When Lisa's science club holds a fundraiser, she struggles to master the art of salesmanship.
Dressed as the intergalactic crew from their new favorite movie, Planet Protection Patrol, Lincoln and his friends are ready to trick or treat. But things take an eerie turn when people around Royal Woods start disappearing.
To help Lori out, Luan gets her a job at the Burnt Bean, where Luan is the boss.
Lana struggles to shake off Lily when she starts to follow Lana around like a shadow.