Chuck Bartowski is an average computer geek until files of government secrets are downloaded into his brain. He is soon scouted by the CIA and NSA to act in place of their computer.
As Chuck is beginning to adapt to his new life as a spy, a doctor who could possibly "cure" Chuck is murdered. Chuck then begins a high-speed fight for his life, all while trying to decide which of his two new colleagues might be out to get him. Meanwhile, Chuck's sister Ellie invites Sarah to dinner to meet the family.
Chuck needs the help of Morgan and the Nerd Herd to prove that he is ready to become the store's assistant manager. Sarah and John assign Chuck his first undercover spy mission to foil a terrorism plot.
Chuck's latest mission has him raiding a Malibu mansion to grab a million dollar diamond being used to fund terrorism. Tagging along is an attractive but less-than-trustworthy DEA agent.
After his intuition is wrong while working on a stakeout, Chuck feels morally obligated to make things right, even when both Sarah and Casey refuse to help with Chuck's new mission. Meanwhile, Morgan has to participate in a sales competition that could decide his fate at Buy More.
In this Halloween episode Chuck meets a Federal agent just like him: A computer whiz whose brain is important to national security. However, Chuck soon has a personal dilemma arise when he has to decide whether or not to turn the man over to Sarah and Casey or to help him escape his handlers.
Returning to Stanford, the University that expelled him, Chuck has to help a former professor who is a government agent being hunted for a sensitive top-secret file he has in his possession. At the same time, Chuck learns much about himself and about the death of his friend Bryce Larkin.
Chuck must learn to balance a real love life with his cover love life when he meets a charming young woman by the name of Lou. At the same time, his relationship with Sarah gets interesting when the duo must explain their sexual relations with Ellie and Captain Awesome on a double date. Meanwhile, there is trouble when someone is using truth poison in order to retrieve codes for nuclear facilities.
Not all of Sarah's feelings for Chuck may have been a cover, as she finds out, when Chuck begins to date Lou, a sandwich maker. When things couldn't get even more complicated, Lou turns out to be part of a smuggling ring.
Chuck discovers that his former roommate and old nemesis, Bryce Larkin, is still alive, and that a renegade group within the CIA is after the Intersect. Chuck then has to balance helping Bryce return to the legitimate CIA, with the year's busiest shopping day at the Buy More.
While coping with the realization that Sarah still has feelings for Bryce, Chuck must assume his toughest cover yet by going on a mission as Sarah's husband. The team must foil the plot of a politically connected counterfeiter, who may be endangering the lives of Anna, Morgan and Anna's parents. Both Morgan and Anna also find themselves in the cross hairs.
The episode begins with a flashback to the year 2004, where John Casey is involved with a female Russian named Ilsa, who claims she is a photo journalist. Later, in present day, Ilsa returns with a fiancé, named Victor Federov. Things get complicated when it is revealed that Ilsa is a French spy.
Two new characters are introduced, both of whom want to take the Intersect. One is a beautiful, young female enemy agent that works in the Pita Palace next to the Buy More, and the other is a handsome CIA agent who is posing as an undercover police detective investigating a theft at the Buy More who wants to take Chuck into his custody. The former quickly blows Chuck's cover, while the latter kidnaps him and makes him vanish from his former life.
Chuck must prevent a menacing operative from obtaining a device that would ultimately lead to a new intersect. Meanwhile Chuck asks Sarah out on a real first date as Casey deals with a difficult assignment.
Chuck needs to go undercover to seduce a woman named Sasha Banachek, so an old school spy named Roan Montgomery is assigned as his mentor. Meanwhile, Captain Awesome finds himself in need of some relationship advice, and and turns to Morgan, and Lester faces his first problems as assistant manager.
Bryce Larkin returns to town with news about Fulcrum. They have hired a wealthy software magnate named Von Hayes to decrypt information on a stolen chip containing a refresh to the Intersect with highly classified information. Bryce and Sarah have to pose as a married couple at Von Hayes' dining party to steal back the chip, while Chuck has to pose as a waiter. Meanwhile, Morgan has an encounter with the Mighty Jocks at the Buy More.
Chuck goes undercover at Sarah's 10-year High School reunion, where they meet the girl that tortured Sarah back in the old days.
Efficiency expert Emmett Milbarge pays the Buy More a visit to inspect the branch, while a global terrorist looks for Jeff. Chuck needs to socialize with Jeff to find out about his connection to the terrorist. Finally, it all comes down to video games and the prevention of World War III.
At a BioScience conference, Chuck runs into Jill, his ex-girlfriend who broke up with him and later dated Bryce Larkin. He flashes on her boss, Guy Lafleur, who is suspected to be working on biochemical weapons. Chuck is ordered to reconnect with Jill in order to gain more information on Lafleur. Meanwhile, Emmett wants the staff to take CPR lessons including a test.
The team needs to acquire a Fulcrum agent list by solving several riddles left behind by Guy Lafleur. Meanwhile, Emmett tries to find out why Chuck is absent so often and goes after his colleagues to get the information.
After finding out that Jill is a Fulcrum agent, Chuck is ordered to use her to infiltrate Fulcrum. Meanwhile, Ellie is preparing the apartment for Thanksgiving and the arrival of Captain Awesome's parents. Morgan, Jeff and Lester are assigned to guard the store over Thanksgiving.
The team is assigned to survey the Global Launch Agency, when intel shows that someone might penetrate their security. During the surveillance someone intrudes the lab who turns out to be Casey's former sensei Ty Bennett. Meanwhile, Captain Awesome's perfect parents decide to pay Devon and Ellie a surprise visit to help them plan the wedding, and Emmett Milbarge introduces an "Employee of the Month" contest to the Buy More, but the employees start their own contest instead.
Sarah's father, a con artist, comes to meet her, revealing that he conned a Saudi Arabian sheik, Rajiv Amad, out of nearly a million dollars. The sheik turns out to be connected to terrorist fundings, so the General wants Sarah and Chuck to gain intel from Sarah's father, but things get complicated when Amad shows up. Anna wants to take her relationship with Morgan a step further and asks him to move in an apartment with her. Devon lends him some money to buy one, but instead, he buys a car.
Christmas Eve does not go as planned when an amateur criminal on the run from the police crashes into the Buy More and takes Chuck, Ellie, Awesome and the rest of the Buy More gang hostage. In order to protect Chuck’s cover and the safety of the other hostages, Sarah and Casey secretly go in to the store to remove Chuck, but the mission quickly falls apart when Chuck refuses to leave his friends and family behind.
Chuck foils a plan to kill Tyler Martin, an international rock star. Chuck's night out with Tyler leads to trouble. Morgan holds a contest among his fellow employees.
Chuck and Sarah must pose as a happily married couple living in the suburbs, where they meet some interesting characters. Meanwhile, after his wife files for divorce, Big Mike goes on a rampage at work.
Chuck uses his burgeoning spy skills to help keep an eye on Anna for a heart sick Morgan. But their discovery leads to a chance that Anna's new boyfriend may be part of a dangerous gang. Meanwhile, Jeff and Lester nag Ellie into hiring their band, Jeffster!, to play at her wedding.
Chuck gets jealous when Sarah has to seduce a Fulcrum agent. Meanwhile, Jeff and Lester start looking for the "Buy More Babe" as a way of finding a new employee.
Chuck, Sarah and Casey learn about a man called “Perseus” who is behind Fulcrum’s plans to build their own Intersect. While Sarah and Casey are sent to find Perseus, Chuck and Agent Cole Barker are forced to stay in a safety bunker. When the mission takes a dangerous turn, their orders to stay out of harm’s way go out the window. Meanwhile, Morgan tries to convince Anna that moving in with him would be a bad idea
Chuck is contacted by the one person that can erase the Intersect from his mind. He starts having trust issues and doesn't know who to lean for help. Meanwhile, Buy More is having problems with the Buy More from Beverly Hills.
A female agent is sent to evaluate Sarah's performance, when Chuck's feelings for her are revealed. Meanwhile, Morgan, Jeff and Lester are trying to get invited to Captain Awesome's bachelor party.
Chuck's life seems to be coming together, his long-absent father has returned and he landed his dream job. Unfortunately for Chuck, neither turns out to be quite what he expected.
After Chuck's father Steve is kidnapped by Fulcrum, Chuck learns the only chance he has to find him is by putting his trust and life into the hands of the person he trusts the least—his ex-girlfriend Jill Roberts. Meanwhile, the Buy More team tries to sabotage Emmett’s corporate evaluation.
While Chuck and Sarah go on to rescue Steve they realize they have a chemistry together. Meanwhile Morgan becomes a pariah at the Buy More after mistakenly getting Emmett promoted.
Ellie's big day finally arrives and Chuck must save her life and her wedding from being ruined by Ted Roark and FULCRUM.
As the upgraded Intersect, Chuck trains to become a full-fledged spy but hits rock bottom when he flunks out of spy school and loses Sarah in the process. Meanwhile, Morgan comes home from Benihana School to help Chuck get over Sarah.
Chuck gets a new mission when Sarah's best friend Carina comes through town with her fiancé Karl. Things get complicated when Chuck wants to hash out his and Sarah's relationship problems while they're on the mission. Meanwhile, Morgan finds himself in trouble when he lies to Jeff and Lester.
Chuck must use his relationship with Awesome to protect a visiting dictator, Premier Goya, who is the target of an assassination. While Awesome is excited about the prospect of being a spy, Chuck is more concerned about Awesome and Ellie's safety.
When Awesome is mistaken for a super spy by the evil Sydney Price, Chuck must become his handler and show him the spy ropes. While on a mission for The Ring, they meet the mysterious Daniel Shaw. Meanwhile, Morgan gets promoted to assistant manager and must deal with Jeff and Lester's latest hijinks.
CIA agent Daniel Shaw assigns Chuck to his first solo mission in Paris, ignoring Sarah and Casey’s wishes. During the flight to France, Chuck befriends Hannah and flashes on another passenger the imposing Hugo Panzer. Meanwhile, Casey helps Morgan battle Jeff and Lester for control of the Buy More.
Chuck juggles his two lives as he trains new Nerd Herder Hannah and gets his very own asset who is caught up with The Ring. Chuck thinks he can handle his asset all on his own but Sarah and Casey feel the need to intercede. Meanwhile, Awesome must lie to Ellie when she starts to ask questions about Chuck and Morgan, Jeff and Lester do some recon work to learn more about Hannah.
Chuck and Hannah unexpectedly become part of agent Daniel Shaw's latest mission. Much to Sarah's chagrin, she gets paired with Shaw, who seems to be trying to get close to her. Meanwhile, Morgan and Ellie continue their mission to get to the bottom of Chuck's secretive and strange behavior.
Chuck promises to cook dinner for Hannah, Ellie and Awesome but must first assume the identity of the world's most dangerous assassin for his latest mission. Meanwhile, Sarah is determined to keep her relationship with Shaw strictly professional.
Chuck feels like his life is falling apart when he can't flash and gets left behind for a mission. While Shaw, Sarah and Casey go on without him, Chuck finds himself in a sticky situation back at the base.
Casey carries out a side mission for his old commanding officer James Keller that leads to him committing treason. When Chuck learns the dark truth about Col. Keller, he and Sarah set out to break Casey out of jail and clear his name. Meanwhile, Awesome's plan to keep Ellie out of danger gets more difficult when she gets her dream fellowship.
Chuck learns that his latest solo mission will be a final test to see if he is ready to be a spy. Chuck needs to put everything he has learned into action to avoid going back to his old life while Sarah and Shaw observe his every move.
Chuck has his pick of the best CIA agents for an undercover operation, but he has only one girl in mind for the job, Sarah. Casey, Morgan and Awesome team up to help Chuck win her back.
Chuck, Sarah and Shaw reunite to find the Ring operative behind the death of Shaw's wife. Sarah has faith that Shaw is ready for the mission but Chuck is worried about his emotional stability. Meanwhile, Morgan considers leaving the Buy More.
While in Europe, Sarah and Chuck realize they’re traveling on a train with Spanish spies. Even though they’re all alone, they decide to take on these rogue agents. Of course, this impromptu mission doesn’t go smoothly. Meanwhile, Beckman orders her newest “unlikely” spy team – John Casey and Morgan Grimes – to track down the missing couple.
Chuck and Sarah are assigned to train under Craig and Laura Turner, a married CIA team who, despite their impeccable record, hate one another. The Turners' stormy relationship forces Chuck and Sarah to wonder if they're doomed with the same fate. Meanwhile, Casey must train the newest member of the team Morgan.
Chuck struggles with disturbing dreams and now he believes his most recent dream predicts danger for a visiting head of state. General Beckman however, is unconvinced and assigns Chuck to meet with a CIA psychiatrist Dr. Leo Dreyfus. Meanwhile, Ellie gets surprising news and Anna returns to the Buy More to talk to Morgan.
The Ring is closing in on Chuck and Operation Bartowski. Fortunately, Chuck's dad Steven is working hard to save his son. Meanwhile, Casey must secretly protect his daughter from the Ring, and Big Mike receives some serious news about the Buy More.
After his last dream, Chuck asks Morgan to help him on a side mission. Their investigation becomes complicated when Stephen J. Bartowski returns and learns that Chuck downloaded the Intersect 2.0. Luckily, Chuck's father may be able to help his son.
Shaw returns to threaten everything that Chuck holds dear as his friends, family and the woman he loves are all put in mortal danger. Chuck has to find Shaw and stop him before his own world gets torn apart.
Chuck and Morgan go on a rogue globe-spanning mission to find Chuck’s mom. Meanwhile, Sarah and Casey follow a trail to Russia as they investigate the mysterious Volkoff Industries and its operative, Marco. Back at home, Ellie delivers big news to her family.
When Chuck go undercover in Milan, Chuck realizes the "Achilles' Heel" in their relationship, but must set personal issues aside for the mission. Meanwhile, Morgan recognizes a fatal flaw that compromises the new Buy More. Elsewhere, Casey struggles to put down roots in Burbank.
Chuck and Sarah's romantic mission is canceled with the arrival of Hugo Panzer and Heather Chandler. But Chuck grows more interested when the manipulative Heather claims to know a secret about his mom. Meanwhile, as Morgan prepares the Buy More for a huge video game release, he gets a surprise from Big Mike.
Chuck and Sarah try to become better communicators as they join Ellie and Awesome on a trip to Costa Gravas; a forbidden romance may put Morgan at odds with Col. John Casey.
When Colonel Casey's former team returns looking for him, Chuck must decide what he's willing to sacrifice in order to find his mom. Elsewhere, Morgan works up the nerve to reveal a potentially dangerous secret to Casey.
Chuck, Sarah, Casey and Morgan must stop Dr.Stanley (Robert Englund) from releasing a toxin that induces nightmares... Chuck's mother's allegiances are questioned; Lester and Jeff celebrate Halloween at the Buy More.
After their first real fight, Chuck avoids confronting Sarah by going on a rogue mission that leads him to his mom's MI-6 handler, Gregory Tuttle, and a mysterious Russian agent. Meanwhile, Ellie is on her own mission to uncover the Bartowski family's long-buried past.
Afraid that his latest setback is driving a wedge between him and Sarah, Chuck resolves to prove himself by going on a dangerous mission with the overeager Agent Rye. Meanwhile, Morgan and Casey scramble as the "Buy Morons" attempt to uncover the true identity of Greta.
Chuck, Sarah, Casey and Morgan venture into the jungles of Southeast Asia when The Belgian attempts to unravel the secrets of the Intersect. Meanwhile, Captain Awesome and Ellie try to decipher a secret left behind by her father.
It's the day after Thanksgiving and Chuck faces the most awkward of family reunions when mom comes over for dinner—along with the dangerous Alexei Volkoff. Back at the Buy More, Morgan deals with the busiest shopping day of the year as Jeff and Lester hatch their latest scheme.
Chuck tries to create a romantic getaway for Sarah while tracking down a nano-chip at a French vineyard. Lester asks Big Mike for love advice.
Sarah takes dangerous measures to help Mary Bartowski bring down Alexei Volkoff, as Chuck worries that she may be getting in too deep. Sarah, though, must enlist the help of Chuck, Morgan and Casey to complete her undercover mission. Meanwhile, Ellie and Awesome are at odds over what to name the baby.
The mission to take down Volkoff reaches a dangerous new level, while big changes loom at home. As Sarah works to free Chuck’s mom, Chuck and Morgan embark on their own mission to take down Alexei Volkoff. Meanwhile, Casey bonds with his daughter, Alex, while Ellie tries to ease Awesome’s anxieties over fatherhood.
Casey, Chuck and Sarah are sent to Morocco to rescue Roan Montgomery. Morgan plans to meet Alex's mother and Mary spends some time with her family.
Chuck surprises Sarah with her old spy team, The C.A.T. Squad, leading to a mission in Rio. As The C.A.T. Squad works to settle a score with Augusto Gaez, old secrets and grudges come to light. Back at the Buy More, Morgan fends off the advances of Carina, a former flame and frisky member of The C.A.T Squad.
Valentine's Day is interrupted when Chuck and the team are sent on a mission to England to protect a reclusive young heiress, Vivian McArthur. Meanwhile, Casey gets an offer from the mysterious Jane Bentley. Back at home, Ellie and Awesome find an unlikely solution to a parenting problem, as Morgan ponders a big move.
Chuck encourages Vivian to get in touch with her inner villain for a mission. Morgan's search for a new roommate has unexpected results.
Chuck and Sarah suspect Casey is carrying out private missions. Chuck fears the CIA's new operatives will render him obsolete. Morgan settles in with a new roommate. Awesome becomes uncomfortable with Ellie's research.
Chuck is put in charge of a top-priority mission, but his leadership skills are pushed to the limit when there is a murder in Castle. Meanwhile, Awesome takes on a mission of his own when Ellie finds an alarming new hobby. Elsewhere, Morgan's leadership is also tested when his Buy More troops wage war against Large Mart.
A bad day gets worse when Sarah throws Chuck a surprising relationship curveball as the CIA orders Vivian Volkoff assassinated. In order to prove Vivian's innocence, Chuck must put his trust in a dangerous ally her father Alexei Volkoff. Meanwhile, Ellie suspects that her mother is interfering with the search into her father's past.
When Chuck and Sarah get conned out of their wedding money, there is only one man they can turn to for help -- Sarah's conman father, Jack Burton. Meanwhile, Morgan pressures Casey to face Alex's mother.
Chuck and Sarah put aside spy work to have a weekend of debauchery, but Awesome’s plans for Chuck’s big night don’t go quite as expected. Meanwhile, Ellie's investigation into her father's computer leads to a life-changing discovery.
Chuck and Sarah’s wedding prep includes one final detail: ensuring that the mother-of-the-groom makes it to the ceremony alive. Meanwhile, Morgan’s responsibilities as Best Man include his most dangerous mission yet, as he faces Vivian Volkoff. Elsewhere, Ellie tends to the last details of the rehearsal dinner and seeks help from an unlikely source.
Before he can kiss the bride, Chuck must enlist his wedding party to take down Vivian Volkoff and stop her from destroying the big day. When he turns to Alexei Volkoff for help, the CIA sends its toughest agent, Clyde Decker, to stop them.
In the fifth series premiere, without the Intersect in his head or the support of the CIA, the world of espionage is a much more dangerous place for Chuck Bartowski and his team of freelance spies. To start, Carmichael Industries takes on a slick, rich thief named Jean Claude (guest star MARK HAMILL - Star Wars), and a conniving investor, Roger Bale (guest star CRAIG KILBORN - The Late Late Show with Craig Kilborn), who has stolen money from some of the world's most dangerous people. Meanwhile, Morgan helps Chuck with a special surprise for Sarah. Back in the Buy More, Jeff and Lester have taken things to another level with their latest scheme.
As the team takes on a missing persons case, Chuck and company struggle to establish themselves as Carmichael Industries in the face of a rival security firm led by the tough and efficient Gertrude Verbanski (recurring guest star CARRIE-ANNE MOSS The Matrix). Meanwhile, Morgan continues to adjust to the Intersect, while Chuck adjusts to being Morgans handler. Also, the Buy More finds an unlikely spokesperson to help motivate business. JEFF FAHEY (Lost, Grindhouse) and JUSTIN HARTLEY (Smallville) also guest star.
As the team is tasked with finding one of the CIA's "most wanted," Chuck fears that life as the Intersect may be going to Morgan's head and inflating his ego. Meanwhile Sarah helps Casey navigate his relationship with Gertrude (recurring guest star CARRIE-ANNE MOSS). Elsewhere, Captain Awesome makes a startling revelation about Jeff and Lester.
Chuck and Sarah go undercover at a Buy More convention to hunt down an assassin whose mission is to take down the new Intersect. Meanwhile, Morgan must deal with the consequences of having the Intersect. At the Buy More, Jeff begins to show a very different side of himself. DAVID KOECHNER (The Office, Anchorman: The Legend of Ron Burgundy) and CATHERINE DENT (The Shield) guest star.
A mission to track down a computer super virus leads Chuck to return to his roots as a hacker - and to call on his biggest competition, Gertrude Verbanksi (recurring guest star CARRIE-ANNE MOSS), for help. Elsewhere, a new Buy More employee (guest star DANNY PUDI – Community) complicates Jeff and Lester's friendship.
Chuck and Sarah race against time to take down a dangerous computer virus, pitting them against Robyn Cunnings (guest star REBECCA ROMIJN – X-Men, Ugly Betty), a ruthless spy who will stop at nothing to get what she needs. Meanwhile, Ellie and Awesome's date night takes a dangerous turn and Morgan is sent on a special mission to recover Chuck's P.A.N.T.S.
Chuck and Sarah discover who is behind the plot to destroy Carmichael Industries. Meanwhile, Ellie's plans for a perfect Christmas begin to come apart and, at the Buy More, Morgan and the gang must fend off angry customers as a computer virus threatens to ruin Christmas. Comic book legend STAN LEE guest stars. and, in return, gets makeover advice.
Sarah is forced to confront a secret from her past and feels she must do so alone, while Chuck urges her to let him help. When Sarah encounters her original handler, Kieran Ryker (guest star TIM DeKAY – White Collar), she fears that he will harm those closest to her, including her mom (guest star CHERYL LADD – Las Vegas, Charlie's Angels).
While Chuck and Sarah contemplate the next step for Carmichael Industries, Casey's forbidden love, Gertrude Verbanski (recurring guest star CARRIE-ANNE MOSS), walks back into his life with a questionable mission in South Beach. Meanwhile, Jeff's enhanced intelligence leads him and Lester to suspect that something unusual may be happening at the Buy More.
As Chuck and Sarah try to realize a new, safer future, Morgan's past as the Intersect sends them to Vail on one last mission, where they enlist the help of an unlikely source - the legendary BO DEREK (guest starring as herself - 10, Fashion House, Tommy Boy). Elsewhere, Jeff and Lester continue their own spy mission. Recurring guest star ANGUS MACFADYEN (Braveheart) appears as Nicholas Quinn.
When a mission in Japan becomes a hostage situation, Sarah and Chuck must face the merciless Nicholas Quinn (recurring guest star ANGUS MACFADYEN) aboard a speeding Japanese bullet train. Meanwhile, the mission leaves Casey with an impossible decision.
After a harrowing mission, Sarah returns to Chuck with a huge secret. Meanwhile, Ellie and Awesome are presented with a new opportunity that could change their lives. Recurring guest star ANGUS MACFADYEN appears as Nicholas Quinn.
In the series finale, Chuck enlists his family, friends and some unexpected allies as he races to stop Nicholas Quinn (recurring guest star ANGUS MACFADYEN) from destroying everything Chuck has built over the past five years. Recurring guest star LINDA HAMILTON appears as Mary Bartowski.
