This episode recaps all of the seasons of Grey's Anatomy and sets up the spin-off series, Private Practice, by relating Addison's story. It also includes a preview of Private Practice.
Addison goes on a road trip to LA as she is given another job offer in California, although she finds that no matter where she is, drama follows her. While in LA, she helps resolve a surrogacy problem, where it seems the surrogate had unprotected sex with many other guys on the week she was implanted with the fertilized egg. Meredith continues to improve her relationship with her father and step-mother when her step-mother is brought to the hospital. Cristina is having issues coping with her mother and (soon-to-be) mother-in-law.
Addison resigns from Seattle Grace, and heads to the Oceanside Wellness Group in LA where she was offered a job. Although, it seems that Naomi didn't consult the other doctors when hiring her. A father is frustrated with his daughter when she hides the fact that she's pregnant. When complications arise, Addison, Pete and Dell work together to make sure that the baby and the mother survive, as pain-free as possible. Jenny, a woman who has been seeing Violet, starts counting the tiles at a department store. To investigate what triggered it, Cooper and Paul, a shop assistant, assist Violet. Meanwhile, when a man dies of a stroke, Naomi, Sam and Charlotte argue over who should get his sperm - his wife or his mistress.
Addison and Pete treat a recently married couple who are having sexual problems. Cooper is trying to figure out why four siblings are all suffering from the same mysterious illness. Maya tells Naomi she's been hoping her and Sam would divorce since she was in the third grade. Meanwhile, Violet is trying to convince a patient to leave her husband, even though, she is having trouble letting go of her ex-boyfriend who is now married.
Sylvie, a 60-year-old who is going condo-hunting with her boyfriend, is worried that he may only be with her for her cooking. An injured soccer player named Michael is brought in by his coach. After some analyzation, Michael reveals that he thinks he is gay, but doesn't want to tell his homophobic father. Catherine, the mother of a teenager, worries when her daughter won't get out of bed or eat. After the daughter runs away, Catherine tries to track her down. Brian, a 12-year-old, punches a teen for kissing his girlfriend. Later, the teen goes missing. A mother of a toddler goes to a lawyer when she thinks the cops are after her as they believe she knows where her husband is. When a boy asks his parents to fund him to go to rehab - his mothers dismay. A man that can't stop his hands from shaking comes in, and the doctors figure out what's wrong with him.
Watch Video A flirting patient named Andrea causes a male nurse to feel uncomfortable, even though he feels the connection. Later, the same male nurse must treat a woman who is not at all pleased by the fact that she's being treated by a man. He also helps treat a runner named Nicole. A very young girl drops by the clinic because she thinks she may have an STD.
At Oceanside Wellness, friendships are tested and secrets revealed when Addison discovers that Naomi is concealing the practice's financial problems. Meanwhile, Violet wonders what secret Cooper is keeping from her, while Cooper himself has to decide whether or not to reveal a medical secret to a patient. Dell quits his job at Oceanside Wellness Group.
Addison and Sam form a hostile takeover in order to bring the practice out of bankruptcy, as all of the doctors look for additional clients and new income streams, while Violet's friendship with Cooper is on the brink of extinction and a married couple fight for an unethical fertility treatment at Oceanside Wellness.
A disturbed pregnant patient has lost her baby, and Violet must convince her that her baby needs surgery. Meanwhile, Cooper must tell a patient he needs part of his jaw removed due to a fast-growing cancer. Dell must cope with his daughter's absence when his ex has to move for a new job Sam and Addison must hold back their feelings for two unattainable people.
Cooper struggles with the mother of a patient after learning she allows the 12-year old to be sexually active. Violet is jealous after Pete begins dating a patient's mom. Meanwhile, Sam is scheduled to testify at a colleagues trial for malpractice; and Addison continues to fight her romantic feelings for Noah.
Violet is physically recovering from her violent attack at home, but the emotional trauma she suffers from isn't going away, despite the best efforts of Pete and her other friends to help. Meanwhile, Addison and Naomi try to mend their tension-filled relationship, as Sam and Cooper treat a father, who has allegedly attacked his family, after he is stabbed by his wife.
Addison, Sam and Cooper treat the sick child of a homeless teen mother they met while volunteering. Meanwhile Violet has trouble relating to her baby when her feelings about her attack resurface during counseling of a rape victim who is now pregnant, and Cooper's financial woes catch up with him when he's asked to help buy out Naomi's share of the practice.
Katie Kent is apprehended and on trial. Violet is asked to testify against her attacker, but she struggles with whether or not she can face her attacker in court. Meanwhile a serious complication threatens the fetuses of two of Naomi's former patients and Charlotte is determined to convince Addison, Sam and Cooper to let her join Oceanside Wellness Group.
The doctors venture into controversial territory when an unexpected new hire at Pacific Wellcare causes Naomi to struggle with the idea of genetically designing babies and Violet makes a sudden decision to try electric shock therapy on a patient. Meanwhile Addison somehow finds herself alone and with a cat.
Addison and Sam go for a hike in Malibu, they come across an expecting couple trapped in their car after an accident, they then perform urgent field care. Charlotte, Cooper and Violet treat a newlywed who, on his wedding night has taken too much Viagra. Pete and Sheldon go out to a bar together and end up falling for the same girl.
Things get too close for comfort when Addison, Pete and Sam must come together on a complicated case involving a dad-to-be who comes down with tuberculosis and threatens the future of his new family. Meanwhile, with Violet still gone on her Costa Rican escape, Sheldon takes over helping one of her patients, Natasha, to get over her crippling fear of flying, and Naomi finds herself in a bit of a love triangle of her own.
When Addison's patient and the life of the three unborn babies she is carrying as a surrogate hang in the balance, Sam's new girlfriend, Vanessa, and Addison are sharply divided on the course of treatment. Meanwhile Cooper seeks Sheldon's help with a young patient, but their personal quarrels over Charlotte get in the way, and Naomi has a dilemma of her own between William and an unexpectedly charming Dr. Fife.
A husband's decision to pull the plug on his pregnant wife is overruled by a judge, forcing the hospital to keep her on life support until the fetuses she is carrying as a surrogate are able to survive. Meanwhile, Naomi feels betrayed after learning of Sam and Addison's feelings for one another, and she turns to Dr. Fife for support while William is away on business. And unable to cope with the tension, Addison takes the day off with Pete and Lucas.
When famed neurosurgeon Dr. Ginsberg and her team pay a visit to St. Ambrose to save the life of Kayla, Addison is shocked to see Amelia Shepherd - Derek's younger sister on the team. But Amelia's presence causes strife between Addison, Sam and Pete when she claims she can save Kayla's life after Dr. Ginsberg declares nothing can be done. Meanwhile Charlotte seeks from Cooper's with a sex education seminar for the elderly that only leads to more tension between the two, as they try to figure out how to work together.
After her open-ended escape to Costa Rica, Violet has finally returned home and to the practice. Everyone treads a little lightly around her, especially Pete and Addison who have mixed feelings about Violet's desire to reconnect with Lucas. Meanwhile Amelia butts into Sam's personal life, pointing out that he can mend hearts in the OR but can't seem to do that for himself; and Sheldon encourages Charlotte to reconcile with Cooper, while Cooper deals with a young patient who eats everything in sight.
Maya and her unborn baby are fighting for their lives on the operating table, and Addison, Amelia and Fife try everything humanly possible to save them. Meanwhile, Sam operates on an incoming crash victim and later makes a grim discovery; Cooper makes an ill-timed but valiant effort with Charlotte, and the staff’s world gets rocked by an unexpected death.
Despite how Charlotte is choosing to deal with the aftermath of her sexual assault, her fellow doctors think they know what's best, teaming up to pursue criminal charges against her attacker. Pete gets a surprise visitor, his estranged brother, who has come to ask Pete to help release their sick mother from prison.
Addison's mother, Bizzy, aggressively demands her daughter do whatever it takes to save her partner from dying - including working with Dr. Rodriguez once again. Meanwhile Amelia and Pete's medical consultation is complicated when a patient's wife and his mistress disagree on the course of treatment, Charlotte and Cooper try to be intimate with each other again, and Violet considers publishing a personally-revealing book she's written.
Charlotte's attacker, Lee Henry, arrives at St. Ambrose Hospital, injured by his girlfriend and in need of urgent care, and Sam and Charlotte must decide whether or not to save his life. Meanwhile, Susan's health takes a turn for the worse, and Addison's mother, Bizzy, begs her daughter to do everything in her power to help.
Charlotte and Cooper look to forgive each other after revealing secrets during couples therapy, Violet seeks the forgiveness and approval of her fellow doctors after they learn her novel-in-progress will make all of their personal lives public, Sheldon treats a patient who claims to have multiple personality disorder, and Sam and Naomi team up on a case involving a pregnant teen with Down's Syndrome.
Violet's book launch party has finally arrived but Sheldon finds himself attracted to the doctor who criticized her book. A surrogate under Addison and Pete's care is caught in a complicated love triangle. Cooper and Sam must convince a family that their son's health must take a priority over his sports career.
Pete suspects that his brother Adam may be responsible for their mother's illness. Meanwhile, Violet discovers quite by chance that Sheldon is dating Marla Phillips, the doctor who panned her book, and who Violet considers as her archenemy. Cooper's patient is a musical prodigy with a debilitating brain tumor.
Katie threatens to take legal action against Violet for "breach of confidentiality," and although Violet feels that she hasn't done anything wrong, she soon realizes she'll have to defend her actions to more people than just Katie. Meanwhile, Cooper suspects that Charlotte may be hiding some lingering feelings for ex-husband Billy, only to find out that Billy has been hiding some feelings of his own.
The day has arrived for Cooper and Charlotte to marry, but not everyone is in a celebratory mood, leading the couple to second-guess their wedding plans. Meanwhile, the doctors of Oceanside Wellness are torn between the future of their practice and protecting one of their own, as an investigator is sent to question them about Violet's breach of confidentiality case.
Charlotte's painful memories of a horrible tragedy are triggered as Amelia continues her downward spiral; Addison takes one step closer to motherhood when she finally chooses a sperm donor; Cooper faces a difficult decision when he realizes his patient's parents have been drugging their son in an effort to control his supposed ADHD; and Pete's trust issues prevent him from repairing his fragile relationship with Violet.
Amelia’s drug addiction spins further out of control as she plays hooky from work with a new fling, starts writing pill prescriptions for herself, and has a run-in with the cops; Addison and Jake are at odds when they must make the impossible choice between donating their patient’s organs or saving the life of her healthy, unborn baby; Violet begins working at Seaside Wellness again, and Cooper, Charlotte and Mason begin to form a family bond, much to Erica’s chagrin.
The Seaside Wellness group stages an intervention for a defensive and volatile Amelia, who has resurfaced after disappearing on a 12-day drug binge with her boyfriend, Ryan. During the intervention, Amelia mercilessly attacks her friends one-by-one, and Addison, in particular, has trouble seeing her sister-in-law in her present condition.
Amelia makes the hard decision to enter a rehab facility, and finds strength through an 18 year-old girl, as they both go through the painful detox process. Meanwhile, Cooper’s strengthening bond with his son is tested by his allegiance to a patient in need, Pete and Violet’s marriage reaches a tipping point, and Addison collapses from her rigorous fertility treatments.
Cooper struggles with whether or not to punish Mason after he catches him stealing; Pete and Violet find it hard to split time with Lucas now that they're living apart; Addison makes changes in her home life to prepare for a potential new baby; Violet and Jake work with two women and a man involved in a polyamorous triad; meanwhile Amelia returns to the practice and realizes how badly she hurt Sheldon when she was abusing drugs.
Pete, Violet, Sam and Addison adjust to their new, singles lives in different ways. Addison questions how much she wants a baby and confides in Jake, Violet considers an offer to go on a date with a young, hot paramedic, and Sam and Pete have a bachelors' night at a local bar. Meanwhile, Charlotte faces a personal, ethical dilemma when Amelia uncovers a secret about Mason's mom, Erica, and Sheldon refuses to bend to the pressure when an old friend from the police force wants him to rubber stamp a fellow cop suffering from PTSD.
Sheldon counsels Sam's friend, Rick, an Army veteran suffering from PTSD who harbors a secret sexual trauma; Erica and Mason are involved in a car accident that forces Cooper and Charlotte to further come to grips with their future; Violet and Pete struggle to navigate life after marriage when he finds her kissing Scott; and Addison and Jake attend a medical conference they won't soon forget.
Sam finds his estranged sister, Corinne, in jail, heavily medicated and near-catatonic, and brings her to Sheldon for help; Erica begins secret treatments for her cancer and refuses to let Cooper and Charlotte tell Mason; Cooper, Pete and Addison treat the baby of a drug addict; and things between Violet and Scott continue to heat up in the bedroom.
Cooper and Charlotte take Erica to Seattle Grace to meet with Derek, Lexie and Amelia regarding a very risky surgery; Scott tells Violet that he would like to take their relationship to the next level; and Addison finds herself caught in the middle of Sam and Jake's fight about a patient. Meanwhile, Sheldon warns Sam to be cautious as he deals with the return of his sister, Corinne.
Sheldon warns Sam that he may be in over his head when he insists on releasing Corinne from the hospital and caring for her at home; a badly beaten Scott arrives at the ER and is placed under the care of Pete; Amelia is encouraged to make a decision about her unborn child; and Jake's daughter grills him on his love life when he visits her at college. Meanwhile, Erica's health takes a turn for the worse.
As Erica's condition worsens, Cooper and Charlotte try to prepare Mason, who's in denial, for the worst; Violet and Pete find that they still have feelings for each other; Addison encourages Amelia to embrace her impending motherhood; and Sheldon and Jake treat a pregnant woman who was jailed for killing her other two children.
Pete and Violet enter marriage counseling to help patch up their relationship; Amelia shuts down emotionally and avoids her peers upon hearing some devastating news; Addison adjusts to the new man in her life, and Charlotte and Cooper struggle with Mason when he refuses to speak to them. Meanwhile, Violet becomes suspicious of the sister of one of her patients.
Addison, Pete and the team treat an illegal immigrant facing deportation who self-induces her pregnancy so that her child will be a U.S. citizen; Cooper and Violet work with a young girl who has gender identity disorder - and with her parents -- and Violet wants to continue therapy with Pete before they begin dating again.
When a patient's partner and father are heatedly divided on his health care, Pete makes a decision that impacts everyone, including himself; meanwhile, Jake offers strength and experience to Amelia when he suspects she's being tempted to substance abuse, Sheldon and Violet treat a family concerned about the father's new sexual appetite, and as baby Henry draws Addison and Sam closer, they struggle to define their relationship.
Addison settles into her new life after making a decision between Jake and Sam; Violet fears the worst when Pete doesn't show up to his preliminary court hearing; and Charlotte swears Cooper to secrecy when she receives shocking news. Meanwhile, Amelia celebrates one year of sobriety and Sheldon rekindles a romance with his ex-wife.
Amelia, now sober for more than a year and on the mend emotionally, goes on a series of disastrous blind dates set up by the other doctors at the practice. After vowing to be alone indefinitely, she teams up with James on a medical procedure, which leads to dinner — and the dinner leads to something completely unexpected