Instead of sleeping in and ordering pizza, per his normal Thanksgiving custom, Jimmy invites Hope's other grandparents, Dale and Margine, to join the Chances for a more traditional holiday dinner. The Chances soon realize that the apple doesn't fall far from the tree when Dale and Margine kidnap Hope, and it's up to them to get her back.
Jimmy hasn't had any time to socialize or make friends since Hope was born, so when he meets another single dad at the grocery store, he immediately sets up a play date. But when Jimmy finds out that Virginia is his new friend's housekeeper, Virginia insists that Jimmy cancel the outing. In an effort to keep the peace, Jimmy and his friend arrange a dinner at the Chance house.
When Sabrina points out to Jimmy just how many germs are lurking around his house, the Chance family becomes obsessed with cleanliness. Finding it impossible to keep Maw Maw clean, they move her to the backyard greenhouse, but after watching some old family movies, they discover a surprising secret that has kept them healthy all these years.
Virginia's cousin Delilah, who struggles to make ends meet, pays a visit to the Chance family unannounced, determined to claim her share of Maw Maw's - whom she thinks died years ago - estate. Further tension builds when Delilah admits she still has a crush on Burt. Meanwhile, Jimmy babysits Maw Maw and panics when she takes off on Sabrina's moped.
When Jimmy watches a home video of himself as a thirteen-year-old, he discovers that he was a musical prodigy with a promising career as a singer and pianist until a horrible accident involving a golf putter rendered him talentless. Jimmy recruits Burt, Virginia and Maw Maw to help him rediscover his lost abilities.
When Burt discovers that Sabrina is the daughter of his wealthy new client, he lets the family in on her secret. Embarrassed by her family’s wealth she reluctantly introduces the Chance family to her father, Cap. Meanwhile Jimmy decides Hope should have rich friends and begs Sabrina to take him to her sister’s party where Sabrina’s insecurities become apparent.
In this "It's a Wonderful Life" themed episode, Jimmy is transported into a cinematic dreamlike state and watches on at a world where he never met Lucy. When he returns to reality he realizes that if Hope had never been born, his life wouldn't be as good. Meanwhile, Virginia, Burt and Maw Maw see a movie that bares a striking resemblance to their day-to-day lives.
Burt hires Barney to help him with his receipts during corporate tax season, and while caught up in the stress Burt accidentally makes a mean comment about Virginia's job, so she decides to change careers and become a tarot card reader. Meanwhile, Sabrina contemplates moving to Africa with Wyatt, upsetting Jimmy.
Sabrina is arrested at a protest for civil disobedience, but her two-week sentence in jail is made even worse by a prison attendant who claims that they're old friends. Meanwhile, Virginia saves the Natesville mayor from a public scandal, but Jimmy's political encounter could threaten Sabrina's freedom.
Grab your red cups and join A is For’s Martha Plimpton and other Raising Hope cast members for drinks and chit-chat. Expected to attend are Greg Garcia, Shannon Woodward, Garret Dillahunt, Lucas Neff, Baylie Cregut, Rylie Cregut, Eddie Steeples, Kate Miccucci, Gregg Binkley, Carla Jimenez, and Todd Geibenhain! Hear behind-the-scenes stories from the cast, including their memories of the brilliant Cloris Leachman.