Professor Nick Cutter is investigating the sighting of a dinosaur, apparently. A species which has been extinct for 200 million years. With his team, they travel to the region where it was sighted to explain how it appeared. However, as they investigate the dinosaur, a weird creature seemed to be killing anything on its path.
This week the team face a huge rhinoceros-like creature and have to deal with a mysterious woman from the future named Eve (who should be very familiar to players of Primeval Evolved ). A herd of embolotherium have come through an anomaly at an off-road motor course, causing one man to have the worst stag night ever. The team arrive but these seven tonne rhinoceros-type beasts from the Eocene do not budge easily. To make matters worse Abby realises someone is trapped in a tent and for some reason one of the embolotherium seems intent of trampling it. Abby and Sarah try to rescue the trapped civilian whilst Connor tries to lure these lumbering creatures back into the anomaly through which they came without causing a stampede or being crushed in the process. Danny finally arrives, with the enigmatic Eve in tow, but is he too late to stop a stampede?
The team split up to face two threats. Danny, Abby and Connor travel back to the future determined to stop Helen before she can hurt anyone else. Meanwhile Sarah and Becker must head to Christine Johnson’s headquarters where an anomaly has re-opened. In the future, Danny, Abby and Connor find Helen, but she manages to escape through an anomaly. Connor works out a way to follow her and they endure a harrowing journey back through time via several anomalies, encountering future predators, raptors and pterasaurs along the way. At Johnson’s office, Sarah and Becker come under attack by three vicious megopterans. At first they try to fight these dangerous insects, but when Becker loses his weapon in the battle, they have no choice but to run. During Danny, Abby and Connor's prehistoric travels one of them comes face to face with the earliest humans, hominids, in an encounter that will change their life forever.
A mysterious group come through an anomaly in a theatre, unknowingly followed by deadly tree creatures. As they attempt to escape, Matt inadvertently brings one of the group – Emily - back against her will. She promises to help him find the creature, in return for going back through the anomaly. In a frantic chase through the city, they track the creature down, only to discover the anomaly has closed, leaving Emily stranded.
Saturday detention is thrown into disarray when a deadly Therocephalian attacks a teacher, allowing the kids to run riot. The team are soon faced with not only tracking down the creatures, but fighting against the antics of a group of terrified students. Finding a Therocephalian nest in the school canteen, Connor enlists the help of the kids to stun the creatures into submission before returning them through the anomaly.
Connor and Abby are sent to a coastal village, where there have been indications that an anomaly has opened, however it is fluctuating. Once there they discover a Labyrithodont, which has been attacking the local cattle and killed a tourist. Matt follows the tracker Emily carried to a cemetery where Ethan has taken her and finds Emily bound and gagged inside a coffin, but Ethan escapes. Gideon warns Matt that Ethan presents a terrible danger to humanity.
An anomaly allows a pack of Hyaenodons to make their home in the wine cellar of a stately home, where Jenny Lewis is getting married. They eat the wedding planner. Connor, Abby and Matt subdue them after battle using medieval weaponry. Meanwhile Becker narrowly escapes a lethal boobytrap set by Ethan; and Gideon is revealed to be Matt's father and from a post-apocalyptic future, then he dies from illness.
A pair of anomalies opens in a prison, one to the Pliocene allowing a terrorbird to attack, and Danny Quinn to return. He meets Ethan and realises he is his lost brother. Matt reveals he is from the future and trying to prevent an apocalypse involving the anomalies. Emily returns to the 19th C and both Danny and Ethan to the Pliocene. Connor discovers that the incidence of anomalies is increasing and potentially dangerous.
When a nuclear submarine encounters an anomaly and Liopleurodon in the sea, the team are called aboard to help. They soon find themselves under attack and get sucked back through an anomaly, with Liopleurodons damaging the outside of the sub. The team must not only capture the panicked Eustreptospondylus aboard, but fix the sub exterior in order to get home.
Following a displaced raptor through an anomaly, Matt ends up in Victorian London. Realizing its to blame for several gruesome murders in the area, he tracks it down only to find Emily attempting to do exactly the same thing. Meanwhile, back at the ARC, Abby knows she has to try and reconnect with Connor; they've been spending too much time apart. But a nasty encounter with April on the way to his lab makes her wonder if Matt is right - Connor is up to something in his lab that she isn't meant to know about.
The exhausted ARC team struggle to cope as more anomalies are opening. As the whole team lets Lester in on the secrets of Matt's mission, they're interrupted by worrying news - anomalies are opening everywhere and there are reports of a huge creature loose on the streets. Matt knows this is something important - the time he's been waiting for is now.
Connor has disappeared through Philip's anomaly, and Matt thinks that his mission is over, Philip has won. But he can't leave Connor to his fate and jumps through the anomaly only to find himself in a barren desert world, with Connor struggling in the immense heat and deadly sun's rays. It's the world of Matt's nightmares, and they are soon being stalked by mutated Future Predators.