When beautiful-but-vapid model wannabe Deb has a fatal car accident, she suddenly finds herself in front of Heaven’s gatekeeper, Fred, who declares her a self-centered "zero." Outraged, she attempts to persuade Fred to return her to her shallow existence but is accidentally relegated to the body of the recently deceased Jane Bingum. A brilliant, thoughtful and plus-size attorney with a loyal assistant, Teri, Jane has always lived in the shadow of her more comely colleagues whereas Deb has always relied on her external beauty. Now, by a twist of fate and a bolt of divine intervention, Deb must come to terms with inhabiting Jane’s plus-size frame in the ultimate showdown between brains and beauty.
Jane’s past catches up with her when a case from the prior year is up for retrial. Jane has difficultly containing her emotions and is thrown in contempt of the court and ends up behind bars. Kim and Grayson sue a shrink who "cured" their client’s husband of his multiple personalities, only she got rid of the wrong one.
Jane defends her - rather Deb’s - mom in a divorce suit when Grayson turns down her mom’s request since he is already representing Deb’s dad. Deb gets a chance to spend time with her mom Bobbi and starts to learn to let go of her old life. Kim represents a dog owner who sues a pet cloning company for breach of contract as he feels this clone is NOT the same dog as his first dog, who was a Westminster champion.
Deb is only 24 but faces Jane’s 32nd birthday on the horizon. When she takes on a pro-bono case for a man who was wrongfully incarcerated and freed 10 years later, she realizes she has lost of eight years of her own life. Kim and Grayson must defend a man who created a website for married couples looking to cheat.
Jane represents a soccer mom who is brought to trial for jumping bail and evading arrest for a crime she committed 20 years prior. Grayson’s client, an aging actor, claims the papers falsely ran his obit. When Grayson gets a retraction, the client still isn’t happy and Grayson realizes the man needs something more than legal attention.
Deb is faced with attending Jane’s high school reunion and finds her work cut out for her when she has to prove a man’s sanity when she is hired by an eccentric business man. Kim and Grayson disagree over what to do when a jilted bride-to-be wants to sue her maid of honor after she discovering her fiancé is sleeping with her.
Jane is outraged when she discovers an upscale women’s boutique refuses to carry any plus-sized clothing. Despite opposition from Parker, Jane enlists Kim to represent her when she decides to sue them. Parker puts Grayson on a case involving his old friend whose daughter ends up on a Girls Gone Wild video.
Jane takes on a case where a woman believes she was switched at birth but finds she has her own “mommy issues” when she receives an unexpected visit from Jane’s mother. Meanwhile, Kim and Grayson must calm Parker’s nerves on a case for one of his closest friends, when they realize Parker hasn’t been in the courtroom in a long time.
Jane is star struck when she gets to save Deb’s favorite fashion model from a tumble with the law, but soon discovers her idol is in more trouble than she thought. Grayson and Kim take on a pro-bono case where a woman refuses to sell her house to developers because it holds too many memories of her deceased husband. asn’t been in the courtroom in a long time.
Everyone at the firm is up in arms when they anticipate Parker is going to make an announcement of the newest partner. Jane finally makes the decision to move on with her life and forget about Grayson when she learns he has been dreaming about her. Jane also gets an unexpected visit from a man from her past whose sudden appearance throws her for a loop.
To take her mind off of being disbarred Jane has a daydream of working with her idol, Paula Abdul, in a food court. Back in reality, Deb has to deal with Ethan, who has shown up on her doorstep saying he's Jane's husband. At Jane's hearing Tony, a fellow lawyer and new flame, is fighting to keep her from being disbarred. But things fall apart when Kim is called to testify against her.
Jane has to help a man attempt to regain custody, while still dealing with amnesia. Kim and Parker assist an author by figuring out whether she can retain control of the fictional character or if Jonathan Martin (pseudonym the character was created in) has control of it. Kim finds out that Fred is her assistant and Grayson asks every one of the office to pause for a moment and remember Deb's birthday
Jane's next case gets a little complicated when she discovers that the two clients she's representing are married to the same man. Jane has trouble keeping her personal life separate while representing the two clients, while Tony is representing the client that started all the trouble. Kim gets some very good news while dealing with an adoption case. Stacy decides to invent something called an armvvelope but will it be the next must have item?
Just as Jane and Tony finally move their relationship to the next level, Tony receives some news that affects both their futures. When Teri's cousin faces deportation charges, Jane steps in to help with the case. Parker and Kim get closer outside of the law offices, while Grayson decides to sell the house he shared with Deb.
When Jane's mother is unexpectedly arrested, Jane must represent her in court before Judge Summers and reconnect with the father she has never known in order to help her mom. Meanwhile, things between Parker and Kim heat up, and Grayson gets heavily invested in a case involving a Ponzi scheme. Teri attempts to help Fred with driving and dating.
Jane & Grayson defend a member of a famous pop duo. Jane & Grayson think it would be a good idea to join forces with the lawyer defending Vanessa (who is the other half of the duo) soon after Grayson and Vanessa to have an affair both inside and outside the courtroom. This causes Jane to become distracted and have difficulty keeping her mind on the trial. Kim and Parker agree to help a bed and breakfast owner deal with a very discouraging review for the inn.
Jane meets the 'queen of mean' when she represents designer Ellie Tannen who is trying to stop the publication of a tell-all-book by her former assistant. Jane also decides to get back in the dating game and invites Hank the bailiff to a dinner party. Kim and Grayson represent a transgender woman who is feuding with her in-laws over her partner’s property.
While she waits for Grayson to wake up from his coma, Jane takes a case about a pair of celebrities (guest stars Nick Zano and LeAnn Rimes) who were both charged with an accident involving a young girl. The case gets more complicated when they decide they want divorce. Meanwhile, Kim takes a case from one of her former clients who has just got divorced.
Jane represents the mother of a dwarf in a case against a sperm bank as she awaits a post-date phone call from Dr. Bill. Meanwhile, Grayson lands a new client during his bachelor party at a gentleman's club; Stacy's questions about Fred's past spur him to hire a coworker to pretend to be his mother; and Parker tries to get Kim to rejoin the firm.
Jane works pro bono on a murder case for the DA's office, where she learns that old Jane used to work and had a tryst with the current DA. Elsewhere, Grayson represents Stacy when a mother accuses her of persuading her teen to purchase products via her video blog; and Parker thinks Kim is dating, so he asks Fred to snoop.
Jane represents a former sorority-house mother who lost her entire savings at a local casino and wants to prove that the casino is responsible for the loss. Meanwhile, Parker and Kim represent a botanist who cultivated a rare flower and is now fighting her former employer, a museum, for the rights to the plant.
Jane represents an engineer who claims a school is going to be built on toxic soil. But the construction company handling the build is one of the firm's most important clients, and Parker orders Jane to drop the case. Meanwhile, Teri is sued for slander for verbally attacking her high-school nemesis.
While Jane and Owen are enjoying their Roman Holiday in Italy, the firm is on shaky ground under Kim's leadership when she discovers they are in financial trouble. Kim reluctantly dispatches Teri to bring Jane home to take on a lucrative murder case while Grayson comes to terms with his new feelings for Jane. Meanwhile, following the devastating news of Grayson and Stacy kissing, Fred moves on with new girlfriend Ally. Stacy turns to famed relationship guru Nikki LePree, for love advice.
Jane frantically searches for Owen, who went missing after seeing her kiss Grayson just before their wedding. Luke tells Jane that “Old Jane” is back on earth and could be in anyone’s body, even Owen’s. Jane represents a desperate father trying to save his eight-year-old son who’s fighting T-cell Lymphoma when his drug treatment is abruptly terminated by a pharmaceutical company. Meanwhile, Kim takes on the case of a woman whose ex-boyfriend posted nude photos of her on website devoted to ex-girlfriend revenge. Luke is reprimanded for mishandling Jane and gets replaced. Finally, Jane gets an unexpected visitor.
Jane finds herself working side-by-side with “Old Jane”, who’s now in the body of a hot model named Brittney. Together they race the clock to defend a former client of “Old Jane’s” who’s on death row for killing a former classmate. Grayson and Kim take on the case of mild mannered father and mattress salesman, Cyd Pinar, who believes he is wrongfully terminated for dressing like a drag queen. Kim struggles with Parker’s absence.
Jane struggles to keep her personal feelings aside while representing a jilted bride who’s suing the former groom for damages. Kim and Grayson represent a surrogate mother looking for the missing parents of the child she is about to deliver. Stacy gets discouraged when she seeks advice from business mogul Barbara Corcoran about The Pakery. Jane and Stacy have a new houseguest when Paul crashes at their apartment. Kim announces the new partner at the firm, shocking Jane and Grayson.
In an attempt to be professional, Jane and Owen partner on a case of a teenage boy who has been accused of cheating on the SATs. Meanwhile, Kim and Grayson defend the owner of a dog that is accused of impregnating a prized pooch that lives next door. Jane enlists Paul to spy on Stacy when she begins acting strangely.
Jane tries to impress both Owen and the owners of major baseball team by representing their star player when he’s accused of murder. Meanwhile, Kim helps a friend fight for her alimony. Owen’s new assistant, Nicole, helps Grayson mend his broken heart and Teri advises Stacy on what to look for in a sperm donor.
Jane attempts to reconcile with Owen while they work together representing a professor who’s been arrested for smuggling drugs. Kim goes up against Grayson’s ex-fiancé Vanessa in a case where Kim represents a woman fighting for rights to a very successful video game she created with her recently deceased boyfriend. Stacy invites a handful of her exes to a “donor party” where she tries to assess who might be the best sperm donor.
Jane and Grayson represent pageant contestant, Donna, when she's stripped of her crown after claiming the Miss Universal Globe competition has been rigged. As Kim's due date approaches, she represents her formerly estranged father, Larry, when he loses his job coaching a little league team. Stacy continues her crusade to convince Jane that Owen would be her ideal sperm donor. Grayson and Nicole struggle to define their relationship.
Following a long night at a bachelorette party, Jane ends up at the U.S./Mexico border to defend the bride's fiancé, whose bachelor party went south of the border. Jane must get the groom back into the U.S. in time for the wedding. Kim represents a housewife who claims that her online erotic novel has been plagiarized by a major publisher. Meanwhile, a mysterious man appears at the firm, yet his motives remain unclear to the lawyers of Harrison & Parker. Owen struggles with his new role as Stacy’s sperm donor.
Jane represents a woman in a personal injury lawsuit that occurred during a wife-swap exercise while in couples' therapy. A man who incorporated himself hires Grayson and Owen when his shareholders prevent him from marrying the woman he loves. Paul sets Jane up on a blind date in hopes of sparking a new romance. Stacy and Owen question their new feelings towards one another.
Jane defends a woman who has to go into witness protection after she's caught in the middle of a drug bust. Owen represents a teen-star whose reputation is put at risk after a risqué photo is taken of her. Grayson represents a man who hires him to draft an unusual "Love Contract" between him and his new wife.
Jane represents Deb's mother, Bobbi Dobkins, in a scandalous case involving sex solicitation. Owen sends Grayson on a field trip to Wyoming where he has to try a California client's case under Wyoming law. Nicole and Grayson's relationship takes a turn. When Stacy suffers an awkward humiliation at yoga class, a chivalrous Owen comes to her rescue.
Jane offers to represent an Amish farmer in a life or death legal case against a big oil company. Grayson helps a dominatrix try to collect a debt from one of her clients. When Grayson and Jane finally reveal their feelings for each other, they’re interrupted by a visitor who threatens to reveal everything.
Jane is forced to finally tell the truth to Grayson, but his reaction leaves her more lost than ever. Meanwhile Owen gets a visit from his estranged brother Charlie that puts his personal life and the firm at risk. As Jane buries herself in work once again to hide from the problems in her life, she discovers her new pro bono case has high stakes with the U.S. government. With Kim on maternity leave, a new lawyer, Belinda joins the firm and gives Jane a run for her money.
Grayson is shocked when Jane tells him that she is Deb; a prickly new attorney is hired to fill in while Kim is on maternity leave; Jane defends a man accused of setting a fire in a record store where he worked that resulted in a death; Belinda and Grayson represent a couple who were trapped on a cruise ship without food or amenities for five days.
Jane struggles with how to behave around Grayson now that he knows the truth; Grayson represents a widower who wants to honor his wife's last wish to be buried in her backyard, while her parents want her in their family plot; Paul buys a Rolls-Royce for $100; Kim returns to work and enlists Owen's help representing a 12-year-old foster child who is searching for a permanent home.
Pregnant Stacy is concerned when someone suggests her frequent burping is a sign she's having an evil baby. Grayson and Jane are paired together on a case involving national security, but are flummoxed when they're given very little information about their mild mannered client or her charges. Kim represents a family of orphans when their adoptive parents kick them out immediately after home make over show renovations.