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X-Men: Apocalypse

2016
as Moira Mactaggert

X-Men: First Class

2011
as Moira MacTaggert

Troy

2004
as Briseis

Insidious

2010
as Renai Lambert

Instant Family

2018
as Ellie Wagner

Neighbors

2014
as Kelly Radner

Spy

2015
as Rayna Boyanov

Bridesmaids

2011
as Helen Harris

Insidious: Chapter 2

2013
as Renai Lambert

Insidious: The Red Door

2023
as Renai Lambert

I Am Mother

2019
as Mother (voice)

Peter Rabbit

2018
as Beatrix 'Bea' Potter / Jemima Puddle-Duck (voice)

Damages

2007
as Ellen Parsons

Mrs. America

2020
as Gloria Steinem

Platonic (2023)

2023
as Sylvia

The Place Beyond the Pines

2013
as Jennifer Cross

Annie

2014
as Grace Farell

Physical

2021
as Sheila Rubin

Like a Boss

2020
as Mia

28 Weeks Later

2007
as Scarlet

Knowing

2009
as Diana Wayland

Jexi

2019
as Jexi (voice)

Marie Antoinette

2006
as Duchesse de Polignac

Insidious: The Last Key

2018
as Renai Lambert

Sunshine

2007
as Cassie

Bluey (2018)

2018
as Aunty Brandy - Brandy Cattle

The Turning

2013
as Rae

The Tenants

2006
as Irene Bell

Unity

2015
as Herself - Narrator (voice)

Echo Point

as Belinda O'Connor

I Love You Too

2010
as Verity

Dallas Doll

1994
as Rastus Sommers

Wicker Park

2004
as Alex

Adam

2009
as Beth Buchwald

Casanova

2005
as Edith

City of Ghosts

2002
as Sabrina

No Activity

2015
as Elizabeth

They Are Us

as Jacinda Ardern

Juliet, Naked

2018
as Annie Platt

Take Away

2003
as Sonja Stilano

The Meddler

2016
as Lori Minervini

I Love You, Daddy

2017
as Grace Cullen

Gaze

2010
as Rose Byrne

Adult Beginners

2014
as Justine

The Date

1999
as Sophie

The Rage in Placid Lake

2003
as Gemma Taylor

Ezra

2023
as Jenna

Just Buried

2007
as Roberta Knickle

I Capture the Castle

2003
as Rose Mortmain

Irresistible

2020
as Faith

Two Hands

1999
as Alex

Executive Producer

Episode Physical
Don’t You Want Me
2022
Episode Physical
Don’t You Ever Stop
2022
Episode Physical
Let’s Get Political
2021
Episode Physical
Don’t You Go Far
2022
Episode Physical
Don’t You Know
2022
Episode Physical
Let’s Get Down to Business
2021
Episode Physical
Don’t You Want to Watch
2022
Episode Physical
Let’s Get This Party Started
2021
Episode Physical
Don’t You Have Enough
2022
Episode Physical
Let’s Agree to Disagree
2021
Episode Physical
Don’t Try This at Home
2022
Episode Physical
Don’t You Run and Hide
2022
Episode Physical
Let’s Get It on Tape
2021
Episode Physical
Don’t You Want to Get Better
2022
Episode Physical
Let’s Take This Show on the Road
2021
Episode Physical
Don’t You Say It’s Over
2022
Episode Physical
Let’s Not and Say We Did
2021
Episode Physical
Let’s Face the Facts
2021
Episode Physical
Let’s Get Together
2021
Episode Physical
Let’s Do This Thing
2021
Episode Platonic (2023)
Pilot
2023

Guest Star

Episode The Tonight Show Starring Jimmy Fallon
Billy Crystal, Rose Byrne, Chef Nobu Matsuhisa
2014
Episode Bluey (2018)
Onesies
2022
Episode The Tonight Show with Conan O'Brien
Seth Rogen, Rose Byrne, Eric Hutchinson
2009
Episode Late Night with Jimmy Fallon
Ethan Hawke, Rose Byrne, Bruce Jenner, Savages, Quinn Sullivan
2013
Episode Today
June 3, 2010
2010
Episode Late Night with Conan O'Brien
Jimmy Fallon, Rose Byrne, John Pizzarelli
2009
Episode Last Week Tonight with John Oliver
Episode 79
2016
Episode The Tonight Show Starring Jimmy Fallon
Jim Parsons, Rose Byrne, Isabel Hagen
2022
Episode The Late Show with Stephen Colbert
Rose Byrne, Lewis Black, P.J. Harvey
2017
Episode Hey Hey! It's Saturday
Episode 31
1999
Episode Close Up With The Hollywood Reporter
Drama Actresses
2020
Episode The Tonight Show Starring Jimmy Fallon
Hugh Jackman, Rose Byrne, Kesha
2020
Episode At Home with Amy Sedaris
All About Amy
2019
Episode Off Camera with Sam Jones
Rose Byrne
2018
Episode The Late Late Show with Craig Ferguson
Wolf Blitzer, Rose Byrne
2009
Episode The Late Show with Stephen Colbert
Rose Byrne, Bobby Flay, Weird Al Yankovic
2016
Episode The Tonight Show Starring Jimmy Fallon
Kit Harington, Rose Byrne, Blake Shelton
2016
Episode Today
April 22, 2015
2015
Episode The Tonight Show Starring Jimmy Fallon
Jason Momoa, Rose Byrne, Clairo
2021
Episode The Tonight Show Starring Jimmy Fallon
Rose Byrne, Brad Paisley, Fallonventions
2018
Episode The Tonight Show Starring Jimmy Fallon
LL Cool J, Rose Byrne, Big Sean
2015
Episode Bluey (2018)
The Sign
2024
Episode The Late Late Show with James Corden
Margot Robbie, Rose Byrne, Polo G
2021
Episode The Daily Show
Rose Byrne
2016
Episode Late Show with David Letterman
Ricky Gervais, Rose Byrne, Okkervil River
2009
Episode Jimmy Kimmel Live!
Rose Byrne, Richard Jenkins, In Real Life
2018
Episode Late Show with David Letterman
Rachel Maddow, Rose Byrne, Gavin Harrison
2011
Episode Portlandia
Soft Opening
2013
Episode Conan (2010)
The Man Who Would Be King, But Chose to Sell Home Appliances Instead.
2013
Episode Chelsea Lately
Rose Byrne
2011