While investigating the death of Byers' father the Gunmen stumble onto a sinister government plot to ignite hostilities worldwide and increase arms sales.
A million-dollar check from a possible drug deal leads the Gunmen to a charity organisation run by a CEO named James Bond.
Frohike goes undercover after the Gunmen receive a tip which could lead them to a baker who poisoned members of the French Resistance during World War II.
The Gunmen search for an automobile that runs on water and whose creator disappeared years ago on a trip to Detroit to show his invention to the Big Three automakers.
The Gunmen uncover the link between a popular senator and one of his female campaign workers who died in a highly suspicious accident.
The Gunmen try to help a man who claims his whole life, including his house and his wife, has been stolen from him.
The Gunmen are in over their heads when they match wits with an intelligent chimpanzee who wants to break out of a government-run animal behaviour laboratory.
Byers and Jimmy become inmates at the Texas Department of Corrections and help an innocent man facing execution on death row.
As Frohike, Langly and Byers try to catch a poacher dealing in grizzly bear gallbladders, a hospitalized Jimmy begins to suspect his surgeon is a wanted killer.
The Gunmen keep blowing Yves' cover as she tries to prevent a tango-dancing smuggler from passing on information about new top-secret military cloaking material.
The Gunmen are stunned to find that FBI Assistant Director Walter Skinner is somehow involved in the murder of Byers' old college roommate.
When two stagehands of the "Cap'n Toby" show die on the same day, the Gunmen investigate only to discover the men were FBI agents working in a Chinese intelligence unit.
The Gunmen team up with Morris Fletcher to uncover information about "Romeo 61," a secret government terrorist organisation responsible for decades of major crimes.
Behind the scenes with the cast and crew of The Lone Gunmen.
When Morris Fletcher approaches agents Doggett and Reyes with information related to "Super Soldiers", they turn to the Lone Gunmen. The Gunmen, however, are knee-deep in a bio-terrorist's plot to release a deadly toxin into the population but the Gunmen find that they may have to make the ultimate sacrifice for their cause.
