| Movie | Step Brothers | 2008 |
| Episode |
Moonbase 8 Dry |
2020 |
| Episode |
Moonbase 8 Rats |
2020 |
| Episode |
Moonbase 8 Quarantine |
2020 |
| Episode |
Moonbase 8 Visitors |
2020 |
| Episode |
Moonbase 8 Move the Base |
2020 |
| Episode |
Moonbase 8 Beef |
2020 |
| Movie | Bagboy | 2015 |
| Movie | Les Frères Sisters | 2018 |
| Movie | Bagboy | 2015 |
| Episode |
Funny or Die Presents Holdup; Derek Water's LOL; Totally Crazy |
2010 |
| Episode |
The Henry Rollins Show John C. Reilly & Thom Yorke |
2006 |
| Episode |
Cracking Up Prom Night |
2004 |
| Episode |
Conan (2010) The AARP Guide to Sexting |
2012 |
| Episode |
The Graham Norton Show Episode 13 |
2019 |
| Episode |
The Rosie O'Donnell Show Judge Judy, Philip Seymour Hoffman & John C. Reilly, Don Cheadle |
2000 |
| Episode |
Kathy Griffin: My Life on the D-List Out and About |
2005 |
| Episode |
The Daily Show John C. Reilly |
2003 |
| Episode |
The Rosie O'Donnell Show Teri Hatcher, John C. Reilly, Wayne Brady, Billy Gilman |
2000 |
| Episode |
Disneynature Bears |
2014 |
| Episode |
Tim and Eric Awesome Show, Great Job! Universe |
2009 |
| Episode |
Late Night with Conan O'Brien (in Chicago) John C. Reilly, Vlasta, John Mayer |
2006 |
| Episode |
Late Night with Conan O'Brien John C. Reilly, Jimmie Johnson, The Walkmen |
2009 |
| Episode |
Tim and Eric Awesome Show, Great Job! Dads |
2007 |
| Episode |
Conan (2010) John C. Reilly, Pete Holmes, the Haden Triplets featuring Ry Cooder |
2014 |
| Episode |
The Late Show with Stephen Colbert John C. Reilly, Ken Burns, Mandy Patinkin |
2022 |
| Episode |
Tim and Eric Awesome Show, Great Job! Road Trip |
2009 |
| Episode |
For Your Love The Endangered Species |
1999 |
| Episode |
Tenacious D Death of a Dream |
1999 |
| Episode |
Chelsea Lately John C. Reilly |
2014 |
| Episode |
Drunk History Drunk History Vol. 6 - Feat. John C. Reilly & Crispin Glover |
2010 |
| Episode |
The Simpsons Any Given Sundance |
2008 |
| Episode |
The Late Show with Stephen Colbert John C. Reilly, Kristin Chenoweth |
2022 |
| Episode |
Jimmy Kimmel Live! Will Ferrell, John C. Reilly, Matty Matheson, Rita Wilson |
2018 |
| Episode |
Funny or Die Presents Casual Sex, Mike O'Connell, Sleeping with Celebrities, The Amazing Adventures of David & Jennie, Day by Day, Men of Unquiet Desperation, Space Baby |
2010 |
| Episode |
Saturday Night Live John C. Reilly/My Chemical Romance |
2006 |
| Episode |
The Late Late Show with James Corden Kevin Hart, John C. Reilly |
2016 |
| Episode |
Chelsea Lately John C. Reilly |
2012 |
| Episode |
The Tonight Show with Conan O'Brien John C. Reilly, Dr. Sanjay Gupta, Matt Braunger |
2009 |
| Episode |
NPR Music Tiny Desk Concerts John Reilly & Friends |
2015 |
