Sympathisanten der „Separatisten“ initiieren Mailand eine Demo. Bei der Demo kommt es zu gewaltsamen Auseinandersetzungen zwischen den Demonstranten und der Militärpolizei – Molotowcoctails, Wasserwerfer und Schlagstöcke kommen zum Einsatz. Die Einsatzzentrale der „Gesellschaft für Soziale Wohlfahrt“ beauftragt drei Fratello-Pärchen einzugreifen. Die Cyborg-Girls Henrietta, Rico und Triela sind wie immer bereit, emotionslos zu töten…
While preparing to return to Italy, Jose and Hilshire go to an antique store in France to pick gifts for their partners, Henrietta and Triela. On the train home, Jose has a flashback to when he was assigned to the Balkans and had to leave his younger sister, Enrica, with his older brother, Jean. Back in Italy, Jose and Henrietta join Jean and his partner Rico, as well as Hilshire and Triela, as they chase a group of bombers after they conduct an attack. With aid from all parties, the bombers are captured. Later at the headquarters, Henrietta goes to Jose's room, and finds inside a kaleidoscope addressed to a "Louise Antoinette Rolle," whom Henrietta suspects is Giuseppe's lover. Heartbroken, Henrietta returns to her room, and voices this suspicion to her roommates, Claes and Triela. Claes recalls that the woman in question is the mistress of a nineteenth century author who commonly used the character "Henrietta" in his novels. Pleased, Henrietta joins Jose stargazing, while Claes remarks that the kaleidoscope is likely fake.
Mentre stanno per tornare in Italia, Giuseppe e Hilscher si fermano a comprare dei regali per Henrietta e Triela. Un flashback mostra il passato di Giuseppe. Tornati in Italia, i due "fratelli" e le loro "marionette" partecipano a una missione, insieme a Rico e a Gianni. Successivamente, Henrietta trova nella camera di Giuseppe un caleidoscopio, insieme a una lettera indirizzata a una donna. Henrietta crede sia la fidanzata di Giuseppe, e ne parla con Claes e Triela.
イタリア首相府が秘密裏に設立した超法規的諜報機関、社会福祉公社。そこでは担当官と義体と呼ばれる公社が開発したサイボーグが兄妹(フラテッロ)と呼ば れるペアになって、暗殺を始めとする裏の任務を行っていた。ある日、ローマ市内で行われていた市民デモに便乗する爆弾テロが発生。付近を警戒中だったジョ ゼ・ヘンリエッタ組とジャン・リコ組のフラテッロは、政府に敵対する五共和国派の犯行であることをすばやく察知し、犯人を追跡。駆けつけたヒルシャー・ト リエラ組、作戦2課員らとともに速やかにテロリストを制圧した。任務を忠実にこなす義体たち。「条件付け」された彼女たちは、命令とあれば殺人へのためら いは一切ないのだった。その晩の公社。ジョゼの留守中に、ヘンリエッタはジョゼの部屋で自分へのプレゼントを偶然見つけ箱を開けてしまう。プレゼントに刻 まれた他の女性の名前を見てショックを受けたヘンリエッタは・・・・・
