Invasive Burmese pythons are taking over the Florida Everglades and devouring everything in sight. The only way to stop them is to call in the nation's best swampers: King of the Swamp Troy Landry, his son Chase, legendary gator hunter Bruce Mitchell, and big fish wrangler Zak Bagby. Together with professional snake hunter Bill Booth, the men dive into the underbelly of the Everglades to capture and remove the sinister beasts.
One week into the hunt for invasive Burmese pythons, the swampers venture into the foreboding Everglades Triangle. Bruce, Zak and Bill hunt near a mysterious abandoned rocket silo, while Troy and Chase scour a cattle ranch for one of the world's deadliest snakes: the African Rock Python.
In the third week of fighting monster serpents, hunters face a terrifying reality: the invasion is bigger than they anticipated. With their backs against the wall, Troy, Chase and Bill call upon trackers and thermal drones to get a leg up on the snakes. Meanwhile, Bruce and Zak breakdown in the middle of a swamp that's rumored to be home to the largest serpent in the world--the green anaconda.
As the hunters face their final week in the Everglades, Troy and Chase protect a remote community from an aggressive gang of alligators. Then, the swampers join forces to track down a deadly hybrid python. Will they be able to stop the rise of the super snakes'
Troy Landry, his son Chase and snake expert Bill Booth track serpents into a breeding ground known as Deer Haven; veteran swamper Bruce Mitchell and invasive species hunter Zak Catchem take on the legendary Skunk Ape Alley.
As the hunting season heats up, Troy, Chase and Bill dive into deep water to catch pythons, but might be in over their heads. Meanwhile, Bruce and Zak fear they've bitten off more than they can chew when they venture into Viper Jungle, an area filled with venomous rattlesnakes and moccasins.
The hunters venture into the Everglades Triangle, a remote area known for unexplained disappearances and swarms of snakes. Troy, Chase and Bill team up with drone operators to search the mysterious swamp from the air, while Bruce and Zak make their reluctant return with a handheld thermal device to track the snakes. Can the hunters prevail before the triangle's eerie past interferes?
When Troy, Chase and Bill mount an airboat to hunt an area pythons are raiding alligator nests, an unfortunate mishap could leave them stranded overnight. Meanwhile, Bruce and Zak's journey into an abandoned ghost town with a haunted past, leads them to an unexpected opportunity.
Troy, Chase, and Bill gamble on a long journey into the center of the Everglades, following the migration of giant pythons to the furthest depths of the wetlands. Meanwhile, Bruce and Zak head deep into outlaw country, looking for snakes hiding on a deserted bootlegging trail...but what they uncover is far more shocking than they expected.
When the swampers can't agree on a hunting ground, they make a friendly wager on which team can catch the most snakes and the biggest python. Troy, Bill and Chase try to gain an edge by returning to a profitable honey hole from last season. Meanwhile, Zak and Bruce place their bets on an abandoned Cold War bomb shelter, but soon find themselves in too deep.
As a heat wave grips the Everglades, Bruce and Zak call in canine reinforcements to sniff out serpents hiding from the rising temperature. Meanwhile, Troy, Chase, and Bill hunt the remote jungles of snake island. But when a differing opinion on strategy divides them, Troy soon finds himself alone in the middle of nowhere.
On their final day of the season, all five hunters converge on the northern edge of the Everglades to stop the invasion of serpents into a critical bird sanctuary. But it soon becomes clear they might be too late.
‘King of the Swamp’ Troy Landry teaches long time alligator hunting partner Pickle Wheat the ins and outs of python hunting, but sometimes even the most experienced hunters walk away with scars. Meanwhile, veteran snake hunter Bill Booth and Florida hunter Tes Lee must learn to work as a team if they hope to put a dent in the growing python population. Zak and newcomer Aaron hunt pythons in an ancient canal system and almost get in over their heads. Dusty Crum finds the fight for the Everglades knocking at his front door.
Pickle must face her fear of big cats as she continues to impress Troy with her natural snake hunting talent. Bill and Tes hunt stumble on a rumored government testing facility and find all they can handle. Dusty recruits a new hunting partner with a snake phobia while Zak and Aaron battle pythons and the supernatural.
Troy and Pickle hunt a giant python known as the Night Serpent; Tess convinces Bill to try out new hunting grounds; Zak and Aaron explore a notorious corner of the Everglades; Dusty Crum has an idea to lighten his load.
Troy and Pickle witness how far the pythons have spread; Zak and Aaron take on a new type of beast; Bill and Tess tackle some uninvited guests; Dusty does what he can to prevent an early end to his python season.
Troy and Pickle face a familiar foe while Bill and Tes defend a friend's camp from a slithering invasion; Zak and Aaron's hunt leaves a bad taste in their mouths, and Dusty Crum has a plan to work smarter not harder.
Troy Landry and Pickle Wheat get a tip about a place called the snake pit from a local; Bill and Tes investigate a rock quarry full of pythons; Dusty has a close call with the supernatural, while Zak and Aaron fight to protect the local children.
The battle for the Everglades becomes personal for Troy and Pickle; Bill and Tes venture further north than ever before; Zak and Aaron visit Zak's childhood stomping grounds; Dusty heads to one of his favorite honey holes.
Legendary hunter Bruce Mitchell rejoins the fight with Zak and Aaron. Troy, Pickle, Bill and Tes team up to help a rancher with a serious problem. While Dusty devises a way to light up the night.
Troy and Pickle battle a hyper aggressive breed of python; Bill and Tes try to stay one step ahead of the Army Corp of Engineers; Dusty works on a plan to get the snakes to come to him; Zak and Bruce face off against two foes.
Troy Landry and Pickle Wheat mix it up with some locals; Tes puts her skills to the test hunting without her partner, Bill; Zak and Bruce return to Viper Alley; Dusty hunts for a legend.
Troy and Pickle track a high-tech snake; Bill and Tes search for a new hot spot; Dusty discovers one of his favorite honey holes has changed forever; Zak and Bruce chase the snakes below ground and get a surprise.
Troy and Pickle help a friend look for his lost dog; Bill and Tes search for pythons in a spot ravaged by wildfires; Zak and Bruce investigate an abandoned boatyard; Dusty hunts in an area with a dark past.
Bill and Tes battle the Everglades heat; Troy and Pickle search for a python paradise; a special day for Dusty goes awry; Zak and Bruce try their luck in the Dead Zone.
Troy and Pickle help rid a citrus grove of pythons. Bill is forced to hunt solo for the day. Meanwhile, Brue and Zak mount an airboat to a new honey hole and Dusty responds to a friend's call for help.
Hunters return to the Everglades to find the enemy transformed; giant female pythons learn to hide from their pursuers; the swampers must dive deep into their secret lairs and remove the beasts before the glades are lost forever.
Troy and Tes race a mounting storm; Zak and Bruce battle an invasion of deer-eating beasts; Ashley and Kaylyn search for a legendary monster; Dusty hatches a daring plan to strike it rich.
Ashley and Kaylyn charge onto Bear Ridge; Zak and Bruce answer an urgent call for help; Troy and Tes go into battle to defend a bird sanctuary; Dusty puts on his inventor hat to save the Glades.
Troy and Tes chase a legendary monster; Dusty changes plans on the fly to save a friend; Zack and Bruce bet big on logging country; Ashley and Kaylyn break into a jungle in search of a python honey hole.
As the Everglades suffer a sudden dry spell, Troy and Tes gamble on a voyage to the glades' tree islands. Ashley and Kaylyn hunt along a river full of gators. Zak and Bruce sweat it out on a kayak mission down the canals.
Troy and Tes search for a beast terrorizing a local camp. Ashley and Kaylyn hunt in the wake of Hurricane Ian's destruction. Zak and Bruce return to Monster Highway. Dusty launches a new business venture.
Ashley and Kaylyn enlist the help of a blind hunting dog; Dusty bets his fortunes on Python Palace; Troy and Tes investigate rumors of an old camp infested with pythons; hunting solo, Zak struggles to penetrate a cypress forest.
Troy and Tes hunt in the wake of a prescribed burn; Zak and Bruce try to break a cold streak on Bruce's last day in the Everglades; Dusty confronts an enemy invader; Ashley and Kaylyn hit an unexpected dead end.
Troy and Tes gamble on new hunting grounds. Ashley and Kaylyn follow an old surveyor's trail. Zak and Aaron place their bets on Bad Luck Prairie. Dusty resurrects an old boat to reach distant honey holes.
Legendary hunters try to capture Burmese pythons that are decimating the Florida Everglades and wiping out entire species.
