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Lois's Sister

In the milestone 100th episode, “Lois’ Sister,” Lois’ younger sister, Susan (Laurie Metcalf), pays the family a visit and brings with her expensive gifts for the boys, biting remarks for Lois and a cold shoulder for Hal – whom she has never forgiven for dumping her for Lois. Lois and Susan’s competitive relationship takes a turn for the worse when Susan gives Malcolm and Reese her prize ’65 Mustang convertible. But when Lois discovers that Susan needs a kidney transplant, she puts her anger aside and offers to donate her kidney to Susan, which Susan only sees as the perfect opportunity for Lois to one-up her.

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  • Originally Aired February 22, 2004
  • Runtime 25 minutes
  • Content Rating United States of America TV-PG
  • Production Code #06-03-513
  • Network FOX
  • On Other Sites IMDB
  • Created September 29, 2019 by
    Administrator admin
  • Modified December 5, 2024 by
    nibbs
Name Type Role
Gary Murphy Writer
Tianna Danielle Kenney Guest Star
Lyndsy Fonseca Guest Star
Kate Lang Johnson Guest Star
Abigail Mavity Guest Star
Heather McPhaul Guest Star
Montana Tsai Guest Star
Alyssa Monka Guest Star
Gracie Markland Guest Star
Hayley Erin Guest Star
Kevin Cooney Guest Star
Jasmine Di Angelo Guest Star
Josh Jacobson Guest Star
Laurie Metcalf Guest Star
Chanel Gaines Guest Star
David D'Ovidio Director