Little Bill goes on a treasure hunt in order to find his thing and keep himself occupied on a rainy day. Little Bill learns that things you want can sometimes be expensive, such as a video game. Andrew gets a Space Explorers video game, but the gameplay, sounds and designs are more boring than they expected, and they learn that playing Space Explorers outside is better.
Little Bill's baby cousin Jamal visits and Little Bill learns about babies from Brenda, Big Bill, and Bobby. Little Bill and Andrew pretend to play camp out in the backyard with Bobby.
Little Bill finds a dollar bill and contemplates what to spend it on. At Uncle Al's store, he finally decides to buy small egg-toys. Little Bill complains that he never gets to help with anything at the supermarket. Soon the kids have to pick out a cereal. Little Bill wants to get Choco-Lots, Bobby wants to get Berry Sweet, and April wants to get Puppy Stuff. They then decide that the variety pack is the best.
Little Bill meets Monty, a boy with cerebral palsy on a wheelchair who likes dinosaurs and the boys play dinosaurs and roll around. Little Bill's friend Dorado helps him past the time while their mothers get their hair done at a beauty parlor.
Little Bill takes swimming lessons with his cousin Fuchsia. He is a bit scared of the big pool at first, but soon gets used to it. Late at night, Little Bill is afraid of the dark, especially the "thing" in his closet, but a quilt from Alice the Great helps overcome his fear of it.
A new boy at school named Michael bullies Little Bill and his friends by playing the dozens. At home, Big Bill teaches Little Bill how to stand up for himself and say "so". Little Bill tries to show Michael to the bathroom (lavatory) with many other room visits as well, but when they both gotta go, they find their way back to the lavatory.
Little Bill has had the chicken pox for a week, and has to stay home with Brenda from a blue sox game. While at home, special guests such as the mailman and Miss Murray visit him. Little Bill and his father build a toy sailing ship, but it breaks when a man with headphones in his canoe hits it. So Little Bill and Kiku build a kite to fly with.
Little Bill acts like a big kid after he watches a movie where Captain Brainstorm's dog Sparky saved the planet Yubba and is called a big dog. Big Bill takes Little Bill to his work for the first time to show him what he does.
Little Bill and his friends go to the mall to see Captain Brainstorm in person. At first, Little Bill gets nervous, but then after he tells his Captain Brainstorm story about saving the space explorers, he now feels confident to meet him and they get a photograph with his friends.
Elephant gets lost in the house, so Little Bill and his family try to find him. Little Bill finds a lost parrot with an abnormal talent on top of the phone booth. It barks like a dog and rings like a phone. Because of the parrot missing its owner, Little Bill finds its real home.
Little Bill learns how to make cleaning his room fun, and later they clean Andrew's room as well. Little Bill and his friends and family turn a vacant lot into a park.
Little Bill borrows his sister April's basketball trophy for show and tell, but when at school, his friends lose the ball. Because of that, April does not want to have her trophy anymore. She slams the door in his face. Little Bill fixes April's trophy by putting his cats eye marble on the finger. April takes Little Bill to basketball practice while Alice the Great is at the dentist, but Little Bill gets annoyed when he thinks he doesn't want to go to April's basketball practice.
Little Bill and his family take a road trip to an amusement park, but it rains along the way as they play games. The family spends time at Super Family Fun Land which has the spider and centipede rides and all the other fun rides.
Little Bill wants to be the ring bear at Miss Murray's wedding, but April and Brenda said that he's going to be the ring bearer, a person who carries the rings. Little Bill is disappointed at first, but he decides to give it a try by practicing being the ring bearer with Brenda. Miss Murray marries Dr. Winthrop Clinkscales with Little Bill being as a ring bearer and Kiku being as the flower girl.
Little Bill accidentally ruins Fuchsia's birthday present, a Gooey Bot. He learns from Brenda that he should tell her and Big Bill if something bad happens. Little Bill attends Fuchsia's birthday party, but is concerned when Andrew got the same kind of present as he did.
Little Bill and Fuchsia are playing Wild West until Little Bill falls down, causing him to break his arm. Alice the Great takes him to the hospital, but calls his mother to meet them and comfort him. Little Bill is upset that he has to stay inside due to his broken arm, so he imagines that he is playing basketball, but gets in trouble when he draws on April's door and gets a timeout in his room.
Little Bill forgets to bring his mother's day gift to his mother from school and left it in his cubby. It is up to him to find something else as a gift for his mother for Mother's Day. Little Bill learns how to use a camera, which is not too easy, and Brenda teaches him three steps to taking pictures so he'll be a great photographer.
Little Bill tries to learn how to roll, which he complains about until April teaches him. Little Bill gets stage fright while practicing for a school play and thinks he doesn't want to be the grass anymore, so Ms. Murray helps him do a calming-down trick.
Little Bill faces a tough decision on whom to send to the snack table first as the snack helper. At recess, there is a construction site in the street. While Little Bill and Andrew are snapped out of their imagination, they mess up Kiku's garden. Little Bill and Andrew learn about nature after they picked the buds off the bush.
Little Bill is upset when Andrew calls him a copycat. Little Bill wants to pick out his own clothes for Picture Day.
Monty joins Little Bill's class, and he's eager to help Monty find his way, but Little Bill is helping him too much and Monty says he doesn't want to play with his way, because he never lets him do anything. Later that night, Little Bill needs help with his pajama top, so Alice the Great helps him, but Little Bill acts like what Monty said to him. After Miss Murray reads the "Three Little Pigs" and Uncle Al is at Johnson Elementary School, Big Bill goes to Johnson Elementary School to tell Little Bill's class how his job works. Unlike the "Three Little Pigs", Little Bill is the wolf, Dorado is the pretend straw house, Kiku is the pretend twig house, and Monty is the brick house.
Little Bill unintentionally upsets Bobby when he makes fun of the way Bobby plays the violin at dinner and Bobby is excused to his room. Little Bill finds an earthworm and wants to keep it as a pet, but Brenda tells him that worms don't go in the house. So he takes the earthworm as an outside pier.
Little Bill is jealous of Monty being with Alice the Great when he says that he loves Alice the Great instead of Little Bill. Little Bill misses his mother when she goes on an overnight business trip.
Little Bill, Bobby, and April have a no-talking contest, which becomes a problem when Bobby's watch is about to get thrown out. Little Bill helps Brenda with the laundry and loses one of April's lucky socks in April's absence.
Little Bill is upset that a Captain Brainstorm costume he wanted is sold out, until he makes his own from the stuff in the house. A party occurs at town on Halloween. Later that night, Little Bill finds out he's not scared of Halloween but when he gets to school, he finds out that he is scared.
Little Bill is afraid that Alice the Great will not be home in time for Christmas, due to the fact that she is stuck at Cincinnati Airport. But when her flight was cancelled, she would go somewhere on Santa Claus' sleigh instead so Little Bill wants to write a letter to Santa to bring her home for the holidays.
Little Bill and his family go to the beach and have fun in the sun. Little Bill helps his sick father feel better by recording a song with his friends at their school.
Michael gets homesick when he sleeps over at Little Bill's house. Little Bill helps Michael get used to snow.
Little Bill is concerned about one of the class' pet rabbits, who is pregnant. Little Bill tries to find a place for the baby rabbits (bunnies) to live.
Little Bill wants to learn how to read, which he does at school with the help of a word hunt and the Harry the Helpful Horse book. Little Bill learns how to write letters, and wants to get letters of his own.
Little Bill, Bobby, and April compete against Andrew and his cousins, Rachel and Kevin, but April was being too bossy about winning. Little Bill's entire family plays baseball at a family reunion, but when Alice the Great is unable to run due to a sore knee, Little Bill fills in for her.
Little Bill's spaceship won't work due to a dead battery. His family thinks he's too little. So he makes up a story about him and Max the Alien saving Captain Brainstorm from the giant purple aliens on Planet Bleep Blop, but they soon realize the purple aliens need help. After the story, Big Bill gets a battery for Little Bill's spaceship and Little Bill reaches April and Bobby's basketball, which it rolled under the porch steps.
Mrs. Shapiro is moving back to Hawaii in order to live with her sister Mimi, and Little Bill does not want her to leave, which makes Little Bill disappointed. Little Bill wants to run away to avoid taking a nap, so his family pretends they're running away too to show how much they love him.
Little Bill gets mad at Kiku after she accidentally spills water on his picture and refuses to apologize after he crumples up her picture in return. Little Bill is disappointed when he finds that his parents and Alice the Great are having an adult party and he cannot come. So Little Bill decides to take the party box and bring it upstairs to have his own party.
Little Bill meets Mr. Rojas and his dog, Miguelito (or Lito for short), who had recently moved into Mrs. Shapiro's old house. But Lito then takes Little Bill's hat, Bobby's telescope, and one of April's sneakers. Little Bill spends time at Mr. Rojas's house to watch Captain Brainstorm while Big Bill helps fix Mr. Rojas's car, but after he runs to the backyard with Lito, he accidentally locks himself out. And Captain Brainstorm on TV is still on when the door is locked and Little Bill and Lito are outside.
Little Bill gets up early at 5:00am and Alice the Great takes him for a walk to the park to show Little Bill a goose and her baby goslings. Little Bill and Big Bill camp out in the backyard while Bobby and April go for a school camping trip. Little Bill then gets ready for bed, and packs his things for camping.
Little Bill and Andrew accidentally lost Big Bill's car keys. When Bobby and Little Bill find his dad's keys, Big Bill is not happy about it. So Big Bill takes Little Bill and Bobby to violin practice. Little Bill, Bobby, and April try to take care of Mr. Rojas's dog, Lito. Lito leaves and Little Bill messes up Lito's hair, so Bobby, April, and Little Bill end up fighting about Lito. Alice the Great wonders what was wrong with Little Bill, Bobby, and April while Alice the Great was in her room.
Little Bill gets a new babysitter named Isabel, Mr. Rojas' niece, who he takes some time getting used to. Little Bill does not want Isabel to leave and he is not happy about it, until he finally says goodbye.
After the supermarket, Valencia and Dorado invite Little Bill over to their house for dinner. Little Bill is afraid to try new foods when he visits Dorado for dinner and seems to like it after doing so. Little Bill and Andrew watch Lito do amazing tricks and they try to get Elephant to do tricks, which are unsuccessful. Little Bill wants a dog like Andrew and Mr. Rojas, but Alice the Great tells him that if he remembers all the memories he had with someone, that shows that he really cares about them.
Little Bill feels left out when he wants to go to the park because Big Bill is helping April with her homework on the computer and Brenda is helping Bobby fix his bike. Little Bill thinks he's not important until Big Bill tells him that he really is important like April and Bobby and before the family head to the park, they had to help a baby robin who fell out of the nest when trying to fly. Little Bill wants to cheer up April when she loses the basketball championship, the reason being she missed an important shot.
Little Bill gets a library card and checks out a fictional book about hamsters. The following week, Little Bill has to return it, but he refuses and so, he did after he has the whole story by memory. Little Bill, Monty, and Big Bill are at the library. Little Bill reads with Monty about dinosaurs and borrows it. At home, the boys go to the backyard, but Monty is stuck because his wheelchair won't go downstairs, not even upstairs. Little Bill and Big Bill build a ramp for Monty to make it easier for him to get into and out the backyard.
Little Bill, Fuchsia and their fathers hike to Echo Falls, with the help of a few red arrows. Little Bill wants to catch a fish. On the first boat trip, his attempts are unsuccessful, but with the help of a hot dog, he catches one on the second.
It is Alice the Great's birthday. So Little Bill learns that April and Bobby are making a book for Alice the Great, and Little Bill takes new pictures of her, but soon he accidentally reveals the surprise. When looking at the photo album, Little Bill finds Alice the Great's old wagon, Ol' Lightnin'. It looks old. So Little Bill and Big Bill make it look as good as new and Little Bill surprises Alice the Great Ol' Lightnin' and he wants to ride it with her, but she can't because she's not little anymore. So Little Bill decides to ride Ol' Lightnin' with some gumption while Alice the Great says "Go, Ol' Lightnin', Go!".
Little Bill runs late for school due to his dawdling such as seeing the bird's nest, playing with Elephant, etc., causing him to miss a popular show and tell visit from Kiku's presentation of her cat, Big Debbie, so Alice the Great helps him. Little Bill wants to learn to tie his shoes. Fuchsia was being a bit of a bully and saying teasing things such as your shoes will run away from you if you cannot tie them.
During a blizzard, Little Bill pretends that it is summertime in the wintertime. Little Bill and Michael build a snow race car, but the snowcar melts as it gets warmer outside.
Little Bill thinks he is shrinking. So he tries various ways to get taller until he realized that he measured himself on the wrong side of the head. At the big kids playground, Bobby accidentally scares Little Bill by pushing him too high on the swings. When Little Bill gets stuck on top of the jungle gym, Bobby helps him get down.
Little Bill wants to play an instrument. He and Big Bill go to a music shop, but do not find the right one. Later, Little Bill uses his voice as an instrument. In Little Bill's next song, "Twinkle Twinkle Little Star" he is rehearsing, Elephant leaves his room and watches April rehearsing "Let It Shine". Little Bill does not listen to April's choir instructions. At the church, he finally listens and assists the choir when Tiny is sick.
Little Bill and Brenda are going grocery shopping at the marker until he meets a deaf employee named Angela and learns sign language from April. Little Bill and Andrew look at bugs and they call out to a friend named Neesha, but she does not answer. Little Bill and Andrew are confused at first until they realize that Neesha is deaf and only knows sign language.
April teaches Little Bill how to skate, and Little Bill refuses to get a lesson. Little Bill was firstly skating with April and Fuchsia. Then Little Bill fell a lot in skating. Little Bill then does not want to skate anymore. But when Big Bill watches Little Bill fall, he is happy that he had learned to skate. Andrew, Fuchsia, and Kiku get butterflies hatched out of their chrysalises, except Little Bill is gonna get a moth. So he waits for it to hatch, which is taking a rather long time.
Little Bill and Big Bill go to see the Captain Brainstorm movie, but when he discovers that Elephant is sick, Little Bill has to take care of him. Little Bill wants to get Elephant a best friend. He tries his alien toy, but Elephant doesn't like it. Little Bill asked April to be Elephant's best friend, but she's very happy with her own best friend, Tiny because they have a lot in common. Finally, Elephant tries to be friends with Andrew's dog, Farfey, but he got scared and hides in his doghouse. Little Bill realizes that he's Elephant's best friend.
Little Bill and Brenda have some private time after she and Big Bill dance to their favorite song. First, Little Bill spends time with Brenda at Uncle Al's market, the store, the supermarket, and even spends time with Elephant. Then, Little Bill spends time with his whole family together and he learns that private time is when people share time by themselves. Little Bill and Alice the Great make a new friend, Clarke Terry as they go to the park. Little Bill then said he would not meet Clarke Terry. But soon, he gets used to him. Especially when they sing the "Never" song.