One’s a Greek. One’s a geek. They both go to Cyprus-Rhodes University and they’re related. Poised to become the most powerful girl in the Greek system, big sister Casey is everything an “it” girl should be. Beautiful… vivacious…funny and warm…except to her brother Rusty. He’s the geek; or rather he used to be way back in high school-at least three months ago. Rusty may excel in the honors engineering program, but what he really wants is what the other guys have. Gals. Pals. A scream-your-lungs-out good time. And to pledge a fraternity. Casey is horrified and wants nothing to do with him. But when Rusty sees her boyfriend Evan making it with her rival Rebecca, her baby brother suddenly seems interesting after all. Oddly enough, she’s not the only one interested in Rusty. Evan wants him for his fraternity while Casey’s ex-boyfriend Cappie thinks he belongs at Kappa Tau. His Bible-toting roommate Dale thinks they're all crazy and is praying for Rusty’s soul. But the heavens seem to be ignoring his pleas because Rusty seems destined to become a Greek, no matter how socially inept he is. Which leads one to ponder…how did someone who’s been nicknamed “Spitter” come to be a pledge at all?
It's the first week of school and the first week of rush and neither is going particularly well for Rusty. On his very first night trying to become one with his pledge brothers, he fell asleep on the job. His "brothers" let him know they weren't too happy by leaving Rusty to dash off to class sans shoes, with blue feet and covered in mud. Rusty's professor was not amused.
Everyone is asked to suit up and pick sides as Kappa Tau and Omega Chi go head to head in floor hockey. But that’s not as easy as it looks. Casey is rooting for Evan and Omega Chi, naturally. So much so that she sets Cappie up for a fall. But did she do it to help her man or to get back at Rebecca? Because Casey and Rebecca may be “sisters” but they sure don’t play like a team. When Rebecca learns that Casey of “Casey and Evan” was formerly with Cappie, she uses the info to backstab Casey and get herself promoted to ZBZ’s head of Athletic Support. That’s when Casey shows what she’s made of—no one is going to beat her.
Cappie turns to Rusty for his brain power when the volcano for Kappa Tau's legendary Mt. Vesuvius party fails to erupt. Meanwhile, Casey and Evan are back on track as he introduces her to his powerful parents over dinner. But an unexpected appearance by Rebecca, a Senator's daughter, instantly bonds her to Evan's parents, leaving Casey to feel like an outsider with this blue-blood clan.
In Casey's bid to become president of Zeta Beta Zeta, she tries to win over her sorority pledges by throwing a slumber party that turns scary when the lights go out. Meanwhile, the same stormy night at Cyprus Rhodes University brings trouble for Cappie when he gets an unexpected visit from a beautiful and mysterious girl named Destiny.
As mid-term week approaches, the pressure is building for Rusty as he is determined to maintain his grades while keeping up his social life at the fraternity. Of course, Cappie has the answers for him but is it the right thing to do? Cappie not only presents Rusty with an appealing offer of help but when he is partnered with Casey on a school project, Casey is tempted once again by her past.
Couples are coming together. Couples are splitting apart. There’s Casey and Ashleigh—best friends and sorority sisters since freshman year, now they’re on the outs. Lack of support—Casey for Ashleigh—is the issue. But someone’s waiting in the wings to show Ashleigh she can be a friend, and that someone is Rebecca.
Allies become enemies when both Casey and Frannie are nominated for the title of Omega Chi Sweetheart. Who will prevail in this the ultimate cat fight? Meanwhile, as Rusty's relationship with Jen K. heats up, he longs for more private time with her but his judgmental roommate Dale is always around, making it difficult for the two lovebirds to spend time alone.
When a scandalous story in the college newspaper hits stands trashing the Greek system, the brothers and sisters of Omega Chia, Zeta Beta Zeta and even Kappa Tau are in a frenzy to figure out who the undercover culprit could be. Meanwhile, after navigating some troubled waters with her boyfriend, Ashleigh turns to Calvin for support and even goes so far as to hit on him, only to learn he has a secret.
A broken-hearted Rusty and Casey head back to school for a new semester after the fallout from the newspaper article that turned the Greek system upside down. Under the watchful eye of Dean Bowman and a newly assigned ZBZ national rep, Casey organizes an all-Greek carnival in support of the dean's favorite charity. At the carnival, the Plain White T's return for another performance as the Kappa Tau band. As the newly appointed president of Zeta Beta Zeta, Casey faces the scrutiny of a national representative assigned to come in and get the sorority back on track. But the sorority turns out to be the least of her problems as she struggles as a newly single girl to get over Evan and to accept Cappie's new relationship with her sworn enemy, Rebecca. For Rusty, it is his struggle with the loss of his first love Jen K. that begins to damage his relationship with his fraternity brothers as well as his fellow pledge class. Also, in an effort to help Calvin reclaim his place in the Greek system, Rusty fights hard to help him fit in with the brothers at Kappa Tau but the end result could end up spoiling their friendship.
Kappa Tau and Omega Chi face off in an epic battle of practical jokes complete with waterguns, duct tape and farm animals. Rusty tries to mediate the situation to save his friendship with Calvin but finds it only escalates the rivalry. Meanwhile, Casey learns that the only way to rid ZBZ of Lizzi, the conservative national rep overseeing them, is to forgive Frannie and reinstate her in a "diamond" ceremony.
When the ZBZ girls express their desire to reunite with the Omega Chi's, Casey is put in a position of having to face her past relationship with Evan head on, causing her to come to grips with her feelings about him. Meanwhile, Rusty has a new crush and oddly enough it is Dale who helps him get a date with the girl. However, since Rusty has only had one relationship in the past, his eagerness to find someone new just might backfire.
The parents visit the campus for Freshman Parents Weekend. Rusty tries to hide something from his parents but Casey wants him to come clean in an attempt to get their parents off her case. Everyone takes care of Senator Logan while his daughter tries to have him hate Cappie. Dale seems to be the only one who is happy to see his friendly parents.
The ZBZ girls throw a crazy competition among themselves as they each coach a different fraternity in a series of games. Casey coaches the Lambda Sigs and ends up developing a crush on one of the fraternity brothers. Meanwhile Rebecca tries to coach the Kappa Tau's and, at the sometime tests her relationship with Cappie.
Rusty finds out a secret about Dale's high school friend and fellow Purity Pledge member, but is uncertain to tell Dale what he knows. Meanwhile, Ashleigh, as the new ZBZ president, finds herself in the middle of a battle between Casey and Frannie as they pursue the Omega Chi's for partnership for the coming school year.
Casey faces a hard decision when she learns that Max is planning to go to Cal Tech for grad school and she is offered an internship. She turns to Lauren Conrad (who appears in a dream sequence) for advice. Also, the pledges are put through Hell Week and Rusty is driven to face the challenge no matter what he is forced to do.
Now a sophomore, Rusty gets to participate in Rush Week for the first time and he is determined to land Andy as a pledge for Kappa Tau, but Calvin feels the pressure from Evan to get Andy to pledge Omega Chi. Who will prevail in the battle for the big man on campus? Ashleigh and Casey start to doubt Rebecca's "mole" abilities and begin to question whether she's actually a double-agent for Frannie's new sorority when the ZBZ girls’ rush week “Project Runway” fashion skit is successfully sabotaged by Frannie.
When Casey discovers that Cappie is taking the same women’s studies class taught by Professor Freeman, she knows that it will complicate her relationship with Max. As a result, Casey decides to enlist the help of her new professor to help Max and Cappie get along. Meanwhile, Rusty starts his first elective class in Art History, and as a lucky bonus meets a pretty new transfer student, Jordan. Although he’s nervous about talking to her, he finds the courage to invite her to a KT party. But the night of the party he learns that some guys have all the luck, namely the new KT pledge, Andy. At the ZBZ house, Ashleigh hires a new hasher, Fisher, who draws a lot of attention from the sisters of ZBZ but, Fisher only has eyes for Ashleigh.
Troubled by the recent discovery that Andy hooked up with Jordan, Rusty is hesitant to take Andy on as his little brother. Will Rusty be able to get past the budding relationship to become the big brother Cappie has been to him? When Cappie hears of Rusty’s reluctance, he takes Rusty aside to remind him that he brought Andy as a pledge to the fraternity and it is his responsibility to be the best Big Brother that Rusty can be for him. Meanwhile, when Evan’s real-life brother, Patrick, comes for a visit, their celebration at Dobler’s is interrupted by Cappie and the three end up reminiscing about their old camp days. But later Patrick shocks and disappoints Evan by asking for money. Frustrated by his brother’s actions, Evan takes it out on Frannie. When Casey and Rebecca believe that the thief responsible for stealing the ZBZ food supply is Fisher, they can’t figure out why Ashleigh won’t accept it. But when they dig a little further, Ashleigh reveals the delicious truth.
Casey’s grand-big sister, Kiki , is back at Cyprus-Rhodes University for her wedding and all the ZBZ girls are invited. Amidst all the wedding frenzy, Max decides it’s time to take his relationship with Casey to the next level and gets down on one knee. Meanwhile, with Andy out of town, Jordan ends up dragging Rusty around town to help pick up the flowers for Kiki’s wedding. When the two discover that the order was never placed, they have to come up with a plan of action however, the plan backfires and puts both of them in the emergency room with identical allergic reactions. The unexpected common bond leads them to share a kiss. Rebecca, in the meantime, soon finds herself in new territory as she kisses Ashleigh’s openly gay big sis, Robin, in one of the bachelorette party game sparking Rebecca’s curiosity.
After she falls into a manhole risking her life, coupled with the Kappa Tau's throwing an "End of the World" party, Casey is sent into an emotional tailspin, questioning her relationship with Max and her lingering feelings for Cappie. Meanwhile, Ashleigh faces her own punishment with Pan Hellenic after a complaint is lodged by Frannie for the Homecoming Float sabotage. Ashleigh turns to Casey to help fight the charge, but when Casey gets caught up in her own personal drama, she leaves Ashleigh to face Frannie alone. And with Dale having trouble keeping his cougar girlfriend's sexual advances at bay and Calvin trying his best to resist hooking up with his new hot roommate, Grant. Dale convinces Calvin to go in on a "purity pledge" partnership so they can help each resist their most recent temptations.
Casey finds out about Rebecca and Fischer's secret kiss, but when Rebecca confesses to Ashleigh, she outs Casey for keeping it a secret. When Mr. Cartwright, Mr. Howard, and Mr. Logan arrive for Father-Daughter weekend at ZBZ, they find out about their daughters' feud, and it reflects upon their weekend behavior. At the same event, Rusty gets nervous about meeting Jordan's father. Meanwhile, in an effort to get over their lost loves, Dale and Cappie fawn over the same girl, but they both ultimately get rejected.
It's time for the annual all-Greek "Undie Run", and the Pan-Hellenic board voted strongly against it. In an effort to change the vote, Casey uses her political savvy to enlist IFC president, Evan, to stage a petition signing. Meanwhile, it's nearing the end of the Greek-wide game of Gotcha!, and only Rusty and Jordan are left, which puts a damper in their effort to spend alone time together. Additionally, Evan finds out about Calvin and Grant's relationship and helps them keep it a secret from the rest of Omega Chi.
Shocked to learn that ZBZ has slipped in the ranks down to fourth, Casey is determined to bring ZBZ back to the number one spot by motivating their pledge class to take action, believing that, if they create a cool photo shoot for the Lamda Sig calendar, it could improve their house’s ranking. However new pldge Abby convinces the other pledges to boycott the shoot so, in order to make nice with the ZBZ pledges, Ashley and Casey get them all makeovers. Meanwhile, dissatisfied with her college experience, Jordan wonders how to make her time at CRU more fulfilling and, in an effort to prove his love and commitment for Jordan Rusty decides to lavaliere her. When Rusty divulges his plans to his KT brothers, they warn him of the Kappa Tau curse that occurs when a brother lavalieres his girlfriend. Elsewhere, Cappie helps Evan find a part time job to help his financial situation, but when he meets one of Evan’s new and very attractive co-workers, Lana, he decides to get a job too.
The ZBZ's are still on edge when they hear their candle is responsible for the Gamma Psi fire, and Casey cracks under the guilt, putting the ZBZ house in jeopardy! Hoping to boost morale and her marketing major, Ashleigh enlists Rusty and Dale in a philanthropic "Geek Auction," but it's up to Casey to play dirty to save the ZBZ's, their house and their Greek rank. Find out if Casey can save the day.
Casey is ready to discuss the future with a resistant Cappie, and the situation isn't helped by handsome Washington politician Joel (Sam Page), who encourages Casey to envision a potential career in politics after she volunteers to help him with his voter registration campaign at the Cyprus Rhodes campus. Find out if Cappie is ready to grow up or if he will fall behind.
It's Valentine's Day at CRU and love is in the air! Casey and Cappie are at war over who can come up with the most romantic Valentine's Day gift. Casey also tries her hand at playing Cupid when she sets Katherine up with Rusty in an attempt to get back in Katherine's good graces. Will Katherine and Rusty spark a love connection or will their awkwardness get in the way?
The Hilgendorf family has moved in next door to the Kappa Tau house, and their presence is putting a damper on the KTs' festivities. When their rules get to be too much of an interference, Rusty and Cappie decide to "borg" Professor Tom Hilgendorf - i.e., to bring him in and make him a KT pledge. Once inducted into the Kappa Tau world, Tom doesn't seem to want to leave, making Cappie rethink his plan to eventually graduate. Find out if either Cappie or Tom will finally grow up.
Everyone at Cyprus Rhodes is preparing for Mardi Gras festivities, except for Casey, who must prepare for the biggest test of her life - the LSAT. While Casey continues to push Cappie to declare a major and make plans to focus on the future, he is too busy announcing the next parade at the Kappa Tau Mardi Gras party. Meanwhile, Joel offers Casey some solid guidance and support for the LSAT. Find out how Casey handles two big tests, the LSAT and her attraction to Joel.
Casey and Cappie get a surprise visit from Cappie's parents, April and Tobias who proceed to invite the couple to join them on a camping trip. While at first reluctant, Casey decides to go, in hopes that they may be able to encourage Cappie to choose a major and graduate with her. But she quickly learns that his parents are free-loving hippies who think Cappie should just relax and continue to enjoy his college experience.
The KTs and OXs are preparing for the Gods of Golf Tournament, the winner of which will be named the top fraternity on campus. Meanwhile, the ZBZs are disappointed to learn that the annual Greek Week has been canceled. Casey talks to Katherine, who agrees to bring back the Greek Goddesses Pageant, under the condition that the competition focus more on strength of character and less on looks, of course. Which houses will end the year on top?
The students of CRU are on Spring Break in Myrtle Beach, which means the year is winding down and the seniors have big decisions looming over their heads. As Ashleigh contemplates her job options, Casey is on edge waiting to see where she'll be accepted to law school. While Cappie is busy planning a romantic surprise for Casey's birthday, she worries that not making it into CRU Law could mean the demise of their relationship. Will Cappie and Casey survive Spring Break intact?
The season opens with Casey, Evan, & Ashleigh’s graduation day. Casey and Cappie haven’t spoken since Spring Break and are anticipating saying their final goodbyes to each other, which does not go as smoothly as expected. We then skip to the end of summer and Casey packing up to move to Washington DC for law school. Through some prompting from Evan, Casey learns that the reason she did not get into CRU law school was a result of a bad recommendation from Joel. After Casey confronts Sam, he reconsiders and has his letter rescinded. Casey is accepted into CRU law and decides to stay after all. Ashleigh has moved to New York for an internship that is not exactly what she was hoping for. Evan is attending CRU law school with Casey.
The KT’s decide since they lost several members of their frat last year, it’s time to actually try to recruit pledges. The KTs set up a booth during rush on campus to help with recruiting. Tegan (Charisma Carpenter) shows up to help the ZBZs maintain their newly regained best house on campus title. Tegan and Rebecca argue on how rushing should go and Casey comes to Rebecca’s rescue with a plan to have Dana (Martha MacIsaac) keep Tegan distracted. The ZBZs entertain a potential new pledge Heather, who is Heath’s sister. Dale also entertains the idea of rushing this semester
Rusty, Dale and Dana are hanging out together and Dana suggests throwing a murder mystery dinner party to help Dale socialize. Members of Omega Chi Delta then storm in and take Dale away as he‘s pledged to them. Casey gets a surprise visit one night from Ashleigh, who has lost her job in New York and now plans to stay back at the house. Calvin reveals that he has no major, just like Cappie, but wants to keep it a secret. Meanwhile, Rusty worries that Dale is joining Omega Chi to get back at him, so he devises a plan to get Dale membership into Kappa Tau. But Dale is insulted by Rusty‘s insistence, and goes to Omega Chi‘s hazing anyway. While he‘s there, Rusty and his friends kidnap him and take him to Dana‘s murder mystery party, inadvertently leaving Spidey there to face the Omegas‘ wrath. Dale eventually leaves Rusty‘s party, claiming that he wants to be a part of that fraternity, and that Rusty should care about his own pledge Spidey instead. Casey is having a hard time finding a study group to join in her new law class because of her controversial past. Ashleigh reveals that she actually ran away from her job because she couldn‘t handle it. Katherine (Nora Kirkpatrick) returns to attend CRU Law school.
Beaver goes to class to find he got an F on his paper because it‘s plagiarized. He‘s needs to write a decent, original paper by the next morning or the F stays on his record. Casey talks with Katherine in hopes of forming a study group with her, but Katherine says she doesn‘t like study groups. Beaver meets Katherine, and is instantly smitten. Rusty and Dana are working on a science project together, and Ashleigh joins in to help make their slideshow more presentable. Dana requests to be called a co-inventor on the credits page, but when Rusty finds out, his anger ruins the presentation. The committee likes the invention, but pulls Rusty from the project and gives it to a professional team. Rebecca invites Cappie to the pledge party so she can make Evan jealous. Casey and Beaver team up in search of case summaries for Casey. Beaver accidentally invites Katherine along as they search for notes, much to Casey‘s dismay.
Lasker Parkes (Jonathan Silverman), Peter‘s dad, comes to visit Kappa Tau, and Cappie feels pressure to impress the him. Cappie plans an Everest party for Homecoming, complete with ice luges throughout the house. Lasker wants to know who is Peter‘s big brother in the. Rusty wants to be Peter‘s big brother, but Peter wants Cappie. Meanwhile, Casey tries to convince Ashleigh to find a job and move out, but Ashleigh keeps dragging her feet. Casey and Evan go to an alumni dinner because their law professor will be there. Casey gets into a fight with Ashleigh. To impress Peter, Rusty plans to steal the A&M goat mascot at night, but while they‘re in the process, Dale and some Omega Chi members interrupt with the same plan.
Casey and Cappie wake up together and Casey kicks him out of the house before anyone finds out, claiming that nothing can happen between them. Rusty wakes up from the party completely hungover, and unable to remember what happened. He finds red lipstick on his mouth, and sets out on a search with Calvin to find the mystery girl. Casey and Cappie meet up later and realize that they did not use protection the night before. Casey gets the morning after pill just in case. At ZBZ, the sisters are watching over faculty children during the big game, and Cappie comes over to help Casey, and to prove to her that he‘s matured. Rusty also divulges to Casey that Cappie declared a major. Later that night, Casey and Cappie share a romantic moment in the playground. Meanwhile, Professor Segal (Josh Randall) flirts with Ashleigh, who is still distraught about her undetermined future
Rusty is planning Calvin‘s 21st birthday party at his apartment. Casey and Ashleigh have not been speaking and are afraid to run into each other at the party. A really bad snowstorm hits Cyprus Rhodes shutting down all roads. Since Heath is not able to make it back with the alcohol, the gang of eight decides to walk to Dobbler‘s. Inside Dobbler‘s, the group decides to play the game "Kiss & Tell" where secrets and feelings are revealed.
Kappa Tau faces academic probation when one of their pledges mysteriously receives straight F‘s, the KT‘s suspect Omega Chi and Dale are behind it. Rebecca uses the investigation as her post Evan break up coping mechanism and discovers that Omega Chi is actually playing a trick on Dale. Evan takes revenge on Casey for his break up with Rebecca by attempting to make her look less than capable in her Law school studies.