Comic Trevor Noah hosts the Grammy awards in Los Angeles, with top nominees including Beyoncé, Kendrick Lamar, Adele, Brandi Carlile, Mary J. Blige, DJ Khaled, Terius "The-Dream" Gesteelde-Diamant, Randy Merrill, Harry Styles and more.
| Name | Type | Role | |
|---|---|---|---|
| Sam Smith | Musical Guest | Sam Smith | |
| Brandi Carlile | Musical Guest | Brandi Carlile | |
| Sandra Denton | Musical Guest | Salt-N-Pepa | |
| Spliff Starr | Musical Guest | Spliff Star | |
| GloRilla | Musical Guest | GloRilla | |
| Lil Uzi Vert | Musical Guest | Lil Uzi Vert | |
| Harry Styles | Musical Guest | Harry Styles | |
| Tariq Trotter 'Black Thought' | Musical Guest | Black Thought | |
| Grandmaster Flash | Musical Guest | Grandmaster Flash | |
| Method Man | Musical Guest | Method Man | |
| Bonnie Raitt | Musical Guest | Bonnie Raitt | |
| Stevie Wonder | Musical Guest | Stevie Wonder | |
| Cheryl James | Musical Guest | Salt-N-Pepa | |
| Lil Baby | Musical Guest | Lil Baby | |
| Ice-T | Musical Guest | Ice-T | |
| Kacey Musgraves | Musical Guest | Kacey Musgraves | |
| Melle Mel | Musical Guest | Melle Mel | |
| Big Boi | Musical Guest | Big Boi | |
| Mick Fleetwood | Musical Guest | Mick Fleetwood | |
| Smokey Robinson | Musical Guest | Smokey Robinson | |
| Rakim | Musical Guest | Rakim | |
| Swizz Beatz | Musical Guest | Swizz Beatz | |
| Queen Latifah | Musical Guest | Queen Latifah | |
| Mary J. Blige | Musical Guest | Mary J. Blige | |
| Busta Rhymes | Musical Guest | Busta Rhymes | |
| LL Cool J | Musical Guest | LL Cool J | |
| Sheryl Crow | Musical Guest | Sheryl Crow | |
| Chris Stapleton | Musical Guest | Chris Stapleton | |
| Chuck D | Musical Guest | Chuck D | |
| Nelly | Musical Guest | Nelly | |
| Scarface | Musical Guest | Scarface | |
| Kim Petras | Musical Guest | Kim Petras | |
| Bad Bunny | Musical Guest | Bad Bunny | |
| DJ Jazzy Jeff | Musical Guest | DJ Jazzy Jeff | |
| Naomi Raine | Musical Guest | Maverick City Music | |
| Quavo | Musical Guest | Quavo | |
| Lizzo | Musical Guest | Lizzo | |
| Too $hort | Musical Guest | Too $hort | |
| Missy Elliott | Musical Guest | Missy Elliott | |
| Flavor Flav | Musical Guest | Flavor Flav | |
| Trevor Noah | Host | Trevor Noah | |
| Jill Biden | Guest Star | Jill Biden | |
| Shania Twain | Guest Star | Shania Twain | |
| Madonna | Guest Star | Madonna | |
| Dwayne Johnson | Guest Star | Dwayne Johnson | |
| Smokey Robinson | Guest Star | Smokey Robinson | |
| Cardi B | Guest Star | Cardi B | |
| Jennifer Lopez | Guest Star | Jennifer Lopez | |
| Kid Harpoon | Guest Star | Kid Harpoon | |
| SZA | Guest Star | SZA | |
| Olivia Rodrigo | Guest Star | Olivia Rodrigo | |
| Viola Davis | Guest Star | Viola Davis | |
| Jayla Sullivan | Guest Star | Jayla Sullivan | |
| LL Cool J | Guest Star | LL Cool J | |
| Chris Martin | Guest Star | Chris Martin | |
| Billy Crystal | Guest Star | Billy Crystal | |
| James Corden | Guest Star | James Corden |