Amy Mitchell (Mila Kunis) is a married woman in the Chicago suburbs with two children, Jane (Oona Laurence) and Dylan (Emjay Anthony), who feels overworked and overcommitted. She works as a sales rep for a "hip" coffee company, prepares healthful, hand-packed lunches for her children, does most of their homework, goes to all of their extracurricular activities, and is active in her school's Parent-Teacher Association#PTA, run by the domineering Gwendolyn James (Christina Applegate) and her cronies, Stacy (Jada Pinkett Smith) and Vicky (Annie Mumolo). When she catches her husband Mike (David Walton (actor)) cheating on her with a camgirl, Amy kicks him out and attempts to keep everything together.
Amy (Mila Kunis) is now in a happy relationship with Jesse (Jay Hernandez) and is looking forward to having a simple Christmas. Her plans are derailed when her overly critical mother, Ruth (Christine Baranski), texts her to say that she is coming for Christmas.