In Runcorn there are two nearby pubs: the Mayhew where friends Janet, Donna, & Louise drink; and the Archer, where friends Jonny & Gaz drink. When Donna mentions to Janet that she's looking for a boyfriend, Janet gets her boyfriend Jonny to persuade Gaz to go on a blind date. Despite the misgivings of Donna and her mother Flo, the date in the Mayhew goes well, even after the attentions of Louise who has got a job there as a barmaid, and Jonny, who tries to put a spoke in the wheel of what he sees as a future of joint couple dates. Donna accompanies Gaz back to his bedsit, but her passion is cooled on discovering what he has stacked in his cupboard.
Gaz hasn't called Donna in the week since their date, to soften her up for an undemanding relationship. The girls are weighing themselves, and Louise finds she weighs more than she did at 14 for the first time since then, and goes on a diet and exercise regime. Donna gives up waiting for Gaz, and goes round to his pad, where her mother phones to invite him round for a meal and to meet the family, including Donna's very forward sister Katie. On Gaz's advice, Jonny is trying to treat Janet mean, to keep her keen, but then goes missing, so everyone has to drop what they're doing and go searching for him.
Donna moves her toothbrush into Gaz's flat, and he reacts badly, thinking it's the first step to moving in completely. Meanwhile, Flo is encouraging Donna to move out of the family home. Louise is getting chatted up by Kev, who, from her description, the other two are convinced is gay - it turns out they are right, and Louise decides to make the best of things by becoming a '˜fag hag'. Janet tries various ways to improve her love life with Jonny, but just makes him suspicious, he thinks that she's been sleeping with a bloke named Pedro, who Gaz made up because he was too drunk to think straight.
The lads are winding Janet up with the old one about it being impossible for girls to be as funny as boys. Not one to resist a challenge, Janet trawls through her ‘crack-a-joke' books looking for that killer one-liner Jonny, however doesn't find the fact that he has been fantasizing about Louise quite so funny of course, Gas's advice is to say nothing. Janet is driving everyone mad with her stupid jokes and in a bid to shut her up Gas tells her that Jonny loves Louise. A heartbroken Janet summons a meeting with her friends and lets rip with a torrent of abuse. Unoffended but rather amused by this, the group begin to giggle. Janet is so chuffed at being able to make her friends laugh she forgives them all. Walking home Jonny feebly excuses himself from his Louise fixation by telling Janet that it got her over her joke obsession. Janet gets her revenge by admitting she too has kissed Louise but Jonny takes things that one step too far boasting that he touched Louise's boobs too.
The pitter patter of tiny feet may be just around the corner for Janet and Jonny. Janet turns to Donna and Louise for advice. Louise is her usual tactless self in her reaction, ‘Excellent, I have a single mum friend to show off to my friends at University' while Donna heads to the chemist to buy Janet a pregnancy test. But Janet can't muster up a sample so Donna turns to Flo for hints on possible pregnancy symptoms which, according to Flo, include hot flushes and a passion for Guinness. Jonny has not taken the news about possible fatherhood too well, but several beers down the pub and a talking-to from Louise later he decides that parenthood is perfect for him. When Janet finally has the results from her pregnancy test—Is she or isn't she? And just why is Donna taking such an interest in the whole matter—is there something she needs to tell Gaz?
Donna has moved in with Gaz, but it doesn't take long for Donna to walk out on him! Jonny has found out about Janet snogging Andy and he is furious with her. Gaz suggests he should use this situation for his own benefit, so the worse he makes Janet feel, the more she'll do for him, but Jonny's attitude upsets Janet and she walks out, leaving Jonny very hungry!
After all the arguments, Donna is living with Jonny, while Janet is living with Gaz, but nobody really knows where anybody is! Donna suggests that Jonny should go to Andy's to ask where Janet is, but as much as he tries to hide it, it's clear he is too scared, but not scared enough to steal an engagement ring off him and offer it to Janet!
After a bit of thought and advice from her mum, and Janet, Donna decides that she should try something new with Gaz, but she doesn't realise he's gonna bring Munch home with him! Jonny realises he'll have to ask Janet's dad's permission to marry Janet, and David and Louise don't get off to a very good start in their relationship.
Jonny goes to see Janet's dad to beg for his permission for their wedding, and discovers he has a secret, but its a bit of a different secret to the one he tells Janet! Munch finds Gaz unconscious in the garage, so he calls an ambulance, only to find out that he'd only got drunk, so there's definetly nothing wrong with him! Donna tricks Louise into forgiving her.
Gaz is furious with Donna after he suspects her of cheating on him with David, and even though he forgives her, it makes him none the more happier to discover she wants to go to University with him! Louise tricks David into getting back with her, and then dumps him!! And Jonny finally comes to terms with Janet leaving him!
Janet tells Jonny he has to move out of the house, he now has nowhere to go! Until he meets Kate, the barmaid in the pub, and they get very close! Gaz is still not happy with Donna's plans to become a student, so he challenges David to a drinking contest! But Donna is more interested in Louise's book, which brings the girls to tears! So much so, Janet realises she made a big mistake dumping Jonny, and goes to get him back, only to find him and Kate sharing a kiss!
Janet is still getting over losing Jonny, and Louise wants to move in with her, but a nasty spider gets in the way! Jonny tries to be manly to impress Kate on their first date, but ends up falling off a wall and breaking his foot! Its Gaz's big night, and all his friends have deserted him! Even Donna, who would rather go and watch a play than see him sing! But he has a wild night in The Archer performing Tom Jones songs, but to a very small crowd!
Jonny and Kate can't get any privacy to have sex, so Gaz lets them use the flat, which is all very well, until Donna gets home! Louise decides she needs to get a job after she graduates, but unfortunately discovers a sociology degree won't get her a much better job than working in Pizza Hut! Gaz is upset that Donna has been neglecting him, but Janet is around to comfort him, but unfortunately things get a little bit out of control...
Gaz is feeling guilty about sleeping with Janet, but manages to keep it from Donna and doesn't tell her, although Janet, in a moment of guilt herself, can't help blurting it out to her! The two girls forgive each other, although Donna doesn't quite know the whole story! Louise is graduating so Kate suggests they should have a party at Janet's house, but as Jonny pops round earlier to drop something off, Jonny and Janet realise they still miss each other, and they end up kissing...
Janet has a new boss at the bakery, that turns out to be Louise! But she has a rather different way of doing things! Donna wants Gaz to split Jonny and Kate up, but tells him not to sleep with her, but he ignores this, takes her out on a date, but Donna finds out and stops him from sleeping with her! Kate, however, is furious that Gaz tried to come on to her, and tells Jonny to choose between her or his friends, but its an easy choice for Jonny, and he dumps her!
Gaz has a problem, his penis, or ""Mr Nudge"" as he calls it, isn't working properly, he's tried everything, from fantasies about Fern Britton to wearing a cock ring! Jonny is struggling with single life, he's got no money to buy a pint! Janet wants him to come home, but he can't, he has his pride! Louise gets carried away in her job at the bakery and sacks everyone, but then finds she's been sacked herself! Jonny is still resisting Janet's pleas to make him come home, until he see's what she's wearing...
Janet wants to introduce something a bit more adventurous in to her sex life with Jonny, but Jonny isn't playing along! Gaz is worried what Donna may be getting up too with her tutor, so he storms round to the cafe they're in, and threatens him! He thinks there's a gun in his pocket, turns out, his penis problem has been solved! Louise gets a new job, which puts her in control of Jonny's criminal record, a few alterations are made and the police are after him! They shoot him! Will he live or die? Find out next series!