Yzma wirft ihre abgelaufenen Zaubermixturen in den Fluss und verwandelt dadurch alle Menschen der Stadt in Tiere. Bis auf Kuzco und Malina, die nur das neue H-Kuzc-O getrunken haben. Malina gelingt es, die Brunnenvergifterin zu entlarven - und damit endlich eine tolle Story für die Schülerzeitung zu haben.
Yzma is cleaning up her old potions and wants to throw them into the river. Kronk tries to prevent this and make her recycle. However, she tricks him and they end up in the river. This begins turning all of the townspeople into various animals. Meanwhile, Malina is trying to make the school paper more interesting so she can get into KuzCollege, and she may have just found her biggest story yet.
Malina décide de réorganiser le restaurant Mudka et sa méthode conduit au renvoi de Yata, la serveuse habituelle.
