ANDIE MACDOWELL ("Beauty Shop") tries harder than any guest to play "MYSTERY WORD" with Ellen! MIKE O'MALLEY ("Yes, Dear") makes good on his promise and comes clean about one of his most embarrassing moments. Ellen surprises eight year-old cancer survivor KASSANDRA OKVATH, whose amazing story was featured on "Extreme Makeover: Home Edition." Plus, another highlight from our past 300 shows, CELEBRITY BABIES, and our latest "DANCE WITH ME" tape!
| Name | Type | Role | |
|---|---|---|---|
| Andie MacDowell | Guest Star | ||
| Mike O'Malley | Guest Star |