In 1961, an Antarctic expedition took a harrowing turn: Dr. Leonid Rogozov began feeling feverish, with an excruciating pain in his right side. It soon became clear that he had appendicitis. While Rogozov’s predicament was extreme, appendicitis is not uncommon; affecting roughly one in 12 people. So, what causes appendicitis? And why is this organ so prone to bursting? David R. Flum investigates. Lesson by David R. Flum, directed by Igor Ćorić, Artrake Studio.