The Hayes family is not the typical family; with two sets of twins and a set of sextuplets (including one daughter with cerebral palsy), their daily routine of six loads of laundry the necessity of a fifteen passenger van as their family car is anything but ordinary.
Betty is treated to a day at the spa with Meghan. Meanwhile, back at home, Eric and the other nine children bake a cake and make a card in celebration of their mother's birthday.
The Hayes take a trip to the aquarium during the kids week off from school to see tropical fish, sharks, and seals.
Eric and Betty take Rebecca to Special Strides, a horse farm that focuses on children with special needs. The other children come as well to support their sister, and find out they can have fun there too.
It's Christmastime for the Hayes. Santa Claus visits the sextuplets at school party and the family's orderly plan for opening presents on Christmas is quickly disregarded when things get out of hand.
The Hayes decide that it's time for all ten children to give ice skating a try.
On New Year's Eve, the Hayes family goes bowling, where it's Eric, Betty, and the two sets of twins against the sextuplets. Later on, the children try to stay up until midnight.
12-year-old twins Kevin and Kyle hope to earn new freedoms by taking on responsibilities, which include helping out around the house and looking after the sextuplets.
The Hayes prepare to open their family pool and Betty registers the children for swimming lessons to boost their confidence in the water.
Kevin and Kyle need braces on their teeth, but the teenagers have differing opinions about getting them.
For the sextuplets' fifth birthday, the Hayes celebrate with a party at Bounce U and a visit to the zoo.
Meghan starts a garden in the backyard, with the help of her dad, while the other kids organize their cleaning and other chores.
Betty takes the kids to the beach and boardwalk for some time in the surf and sand.
The family travels to Pennsylvania for some fun at Hershey's Chocolate World and Hersheypark.
The Hayes family shops for school supplies together in order to prepare to go back to school. The sextuplets are starting kindergarten and get to ride the school bus for the first time. Meghan and Kieran start middle school, and Kevin and Kyle are in their last year of middle school.
Eric and Betty take the kids skiing for the first time during a family trip to Camelback Mountain in northeastern Pennsylvania.
The Hayes family grows again when Eric and Betty promise the kids a puppy. However, the kids must prove they can handle the responsibility by completing a long list of spring-cleaning chores first.