Button's has an affair with a woman with a very jealous and murderous ""husband"" while Rocko and Bill take advantage of two prostitutes who have announced a holy mission to see that the terminally ill get laid.
Dan's game with an Ouija board results in Buttons being possessed by a demon who intends to destroy the world and picks Dan as the virgin sacrifice he needs to finish the job.
Cuddle gains the power to heal by touch and becomes known to the neighbours as the Miracle Child but his popularity annoys Dan who sets out to destroy Cuddle's gift until he discovers he has terminal bowel cancer.
In this episode many pizza delivery boys disappear. Rocko and Cuddles decide to take a job delivering pizza. In the meantime, Buttons lies to a pretty lady, (Meredith Henderson), to get what he wants. The truth about Buttons is uncovered though, and the case of the disappearing pizza boys is solved.
Rocko learns he's down to 2% of lung capacity and needs a transplant to survive but he's such a scumbag that no one's willing to donate them to him and he doesn't have the money to buy a new set. Bill's sent to a TV quiz show to earn the money but it turns out his genius at home was actually from cheating and in he's way over his head.
Cuddles' latest blind date turns out to have a siamese twin attached and wants him to find a date for her sister. Rocko barges into the situation and finds he's met his match in the bitter & angry sister. To everyone's surprise their mutual hostility turns into a passionate affair while Cuddles finds that the other sister is far more boring than her personal ad claimed.
Dan encourages Cuddles to be more creative in his artistic endeavours but is surprised when he sees the unusual source for Cuddles' newest creations. When Cuddles is believed to be dead shortly thereafter from an apparent suicide, interest in this ' work ' skyrockets and Bill and Rocko quickly move to advantage of this atmosphere.
Dan's mother arrives for a short visit at the halfway house. After a series of unfortunate accidents, and a little subtle encouragement from Rocko, she begins to believe that Dan has an Oedipus complex. To make matters worse, Dan is told he may fall victim to the Oedipus prophecy that foretells nasty events for him and his parents.
When news comes out that Buttons runs a slave labor factory that produces Buttons the Bear dolls, Buttons looks for a way to restore his public image. Rocko suggests contacting a foundation that grants wishes of terminally ill people but Buttons quickly finds out that granting such a wish isn't a short term fix as he thinks. Meanwhile, Dan is annoyed when Bill keeps interrupting at the most inopportune times and Rocko, with great reluctance, agrees to help out a former prison inmate.
A minister and his wife pay a visit to the halfway house and in a short amount of time, Buttons starts fooling around with the wife, to the dismay of the minister. Meanwhile, Bill is set to marry a woman he has known only briefly even as reports circulate of a beautiful woman killing people at an alarming rate.
Dan and Buttons are involved in a car accident with Buttons left in a near death coma as a result. However, Buttons' ghost appears at the halfway house and quickly makes Dan's life miserable as only he can. Frustrated, Dan resolves to rid himself of the ethereal presence through any means necessary.