Kathy Najimy joins Ryan in the studio.
| Name | Type | Role | |
|---|---|---|---|
| Diana DeGarmo | Guest Star | ||
| Tony Shalhoub | Guest Star | ||
| Brittany Snow | Guest Star | ||
| Ludacris | Guest Star | ||
| Casey Kasem | Guest Star | ||
| Fantasia Barrino | Guest Star | ||
| Eric Powers | Guest Star | ||
| Meg Ryan | Guest Star | ||
| Adam Sandler | Guest Star | ||
| Stuart Scott | Guest Star | ||
| Omar Epps | Guest Star | ||
| Kathy Najimy | Guest Star | ||
| Bob McKinnon | Director |