EMTs in cities across America answer the calls for help from their communities. In Austin, Texas, responders run point in a massive multiple car collision and need to triage more victims than can fit into their ambulance. A combative addict and an overdose gone wrong offer tough challenges in Yonkers, New York, while in Baton Rouge, Louisiana, southern charm is revealed to have its own healing effects. And in Tucson, Arizona, responders do everything they can to avoid delivering a baby in the back of their ambulance.