When football team owner Jock Stryker is killed, suspicion falls on quarterback Randy, a friend of Houston's. Many people wanted Stryker dead, including his abused girlfriend Andrea, his resentful gofer Crusher, and Coach Buck Turley.
Actress Ramona Landers reports to the set of her comeback film. Her young costar Todd Gallagher accuses her of drunkenness, then gulps her drink and dies of poisoning. Houston interviews her husband and those involved with the film.
Restaurant critic Roger Marsden's severed head is served in aspic to his snooty partner J Hamilton Goodfellow. The cops suspect a restaurant owner whose eatery the critics panned. And then attempts are made on Goodfellow's life.
Lifeguards at the beach are being fatally attacked by sharks. Before her daughter Sue becomes a victim, Alice Landa hired Houston to find out if a shark can be programmed to kill.
The son of an Arab King is kidnapped while they're on his private plane while in flight. Later on recommendation of the his personal pilot, an old friend of Houston's, he hires Houston. The King suspects that someone on the plane brought the kidnapper on board. So while he does that, he learns that his son who was on his way for medical treatment has only a little time.
When the owner of a company that manufactures among other things robots is killed by one. Murray asks Houston to help his friend, the designer who was at odds with the man because he was planning to shut his project down. And among the suspects are the man's brother who was battling him for control and an unscrupulous businessman whom Houston knows who was in the building at the time of the incident.
At a hospital fund-raiser, Dr. Belkamp is shot by waiter Tom Chapman, a former orderly whom Belkamp fired for being inept. Chapman is killed while escaping. Did a member of the hospital research team hire him to kill Belkamp? If so, who?
When a boxer goes out to dinner with his wife, doctor and promoter. The doctor's nurse who arrives wanted to talk to the boxer but before she could she gets killed. His wife goes to Houston telling him that she thinks someone might be trying to kill her husband because he's had a few close calls lately. But the boxer doesn't want Houston around.
Cat food magnate Felix Randolph is killed by his pet tiger. The grounds-keeper is arrested but Houston thinks the killer is one of four ex-wives, who accuse each other and cannot lay claim to the estate until the murder is solved.
While being named Commodore of a yacht club, boorish Rawson Harmon IV is killed by a snake. Manager Honey Lewis asks Houston to investigate. Suspects include Honey; her restless son Jeb; sleazy filmmaker Bevak; & gambler Binky.
Houston goes to the office to meet some people who asked to see him. But when he gets there, he learns that they think he asked them to come. But Houston doesn't know all of them. But then one of the guests says that they do have something in common but that's when he's killed. And they find themselves locked in. And that's when someone is sending them messages which are suppose to be hints of why he is targeting them. And more people are getting killed. And more messages are being sent.
When a man Houston sent to prison escapes, he then makes an attempt on Houston but gets Bo instead. Houston tries to flush him by shaking down his old associates. He then learns that the man was broken out by a deranged billionaire who became a serial killer whom he caught, who's been in an insane asylum, so he has to find out how he's doing it. He also finds out that the man has recruited a couple of other men to get Houston.
Womanizing scientist Ivar Mardosian dies of an induced heart attack while in the desert with colleagues awaiting alien contact. Are aliens really visiting, or is this a staged hoax to cover up a murder? And who killed him?
Two men dressed like Laurel & Hardy try to kill C.J. Houston learns that some of her former sorority sisters have already been victims, and that the man that they had been dating could be responsible. But others are marked for murder, too.
During a carnival fund-raiser, vicious gossip columnist Vonda Moran is blown up because someone tampered with a "strength test" mallet & ringing bell attraction. Houston is subsequently kidnapped and persuaded to investigate.
Alcoholic singer Johnny Foster wakes up with blood on his clothes and is arrested for killing several Vegas showgirls. His friend Houston thinks he's innocent and sets out to find the real culprit.
Bloodied gunfire victim Eric Brandt lands in a passing car, hands the driver a codebook, and gives her a message for Houston: Fear for Tomorrow. Brant dies when the car blows up. His assailants then go after Houston's buddy Vince Novelli.
After Houston's friend Winston Fowler's top jockey Cindy Gaines breaches her contract with him to move to England, she is fatally pitch-forked in a stable. Houston is found standing over her remains and subsequently arrested for her murder.
At a mystery writers' convention where Houston is the keynote speaker, publisher Wayne Slocum shoots hated mystery writer Emily Armor three times with a .45 magnum, then brazenly entreats his friend Houston to help solve her murder.
Marquis Duval Sr. kidnaps C.J. and holds her hostage. As ransom, he demands that Houston arrange for his son, whom Houston considers a terrorist, to be released from prison.
While investigating a land scam, Matt finds out a few unnerving things about his family and his past.
A former peace officer is jailed and under arrest for murder, but he might not have committed the crime.
A deranged woman, who Matt briefly dated, stalks him and will kill anyone who gets between them.
Three stunning women have been murdered, their connection: they are all top centerfolds.
Matt must rescue an insulin-dependent, special-needs boy who has been wrongfully deported to Mexico.
As he lay dying from a fatal gunshot, an associate asks Matt to protect Marilyn. Only one problem: Matt has no idea who she is.
A man trying to expose dirty union tactics is murdered right after asking Matt to take the case.
C.J. asks Matt to solve the murder of an old college friend, Connie Ling, who was involved with heroin dealers.
In the attempt to protect her little sister from a child prostitute ring, a teenage call girl is murdered.
A talented art forger is found murdered, and the clues may rest one of his paintings, which is now missing.
Matt sets out to prove that a blind psychic is actually a phony, responsible for several kidnappings and murders.
Matt has to find the connection between the death of Navajo woman and an international beauty contest.
Attorney F. Lee Bailey decides to defend a man who has confessed to killing four teen-agers, then leaves C.J. to handle the details.
Matt sets out to prove that a touring classical pianist is responsible for strangling and murdering several women.
While on a case investigating unnecessary drugging of convalescent patients, Matt is seriously wounded.
Lt. Vince Novelli asks Matt to help clear his name when he is framed for stealing drugs.
A secretary is murdered after uncovering a plot to blackmail her boss.
A serial killer who killed Matt's fiancee in the past reveals that he has struck again.
Matt's ailing father becomes the target of psychopath.
While Matt is out of town, C.J. has to deal with the murder of her boyfriend and an obsessed stalker.
A thief has second thoughts after stealing a cool $3 million from the mob.
Houston wakes up and calls C.J. who tells him that he has been missing for 30 days. He then discovers that he's the prime suspect in a murder. And when the evidence is overwhelming, he goes on the run to prove his innocence.
Houston is still on the run and is trying to find the one responsible but has no leads. But when he meets a gifted child who tells him to seek out the help of his family. But Houston says he has no family except for his Uncle Roy who is a former member of the CIA.
When three children are abducted and one of them is Hoyt's, he and Houston do whatever they have to find her. Eventually they find the man who got them but he claims they're dead. And since Houston and Hoyt didn't exactly go by the book, the man's released. And Hoyt sets out to get him.
Accused of being jealous, Matt is reluctantly faced with proving that C.J.'s newscaster boyfriend is a murderer.
Whether it's a religious cult or a commune, Matt must rescue a girl who is being bilked out of a $3 million inheritance by the evangelist leader who plans to murder her after he has gained control of the cash.
Matt sets out to rescue C.J. who has been mistaken for a prostitute and imprisoned after suffering amnesia in a freak car accident.
Houston and Roy get information that Roy's son who is an MIA in Vietnam is alive.
The Cambodian warlord who has imprisoned Matt's cousin might be getting a little help from someone close to Matt.
Two models have been murdered, and Matt can't accept the alibi of the most likely suspect.
An old enemy of Houston's, Andre 'Allen' Garvey - AKA the 'Wolf-Witch' - is released from prison after bribing a corrupt judge, Malcolm Granger. The fiend begins taunting & stalking Houston on a single-minded mission of revenge.
An old high school friend of Matt's is unaware she is being used as a decoy when she asks for his help to find her boyfriend.
The most dangerous game is revisited when a sporting goods mogul hunts athletes.
Matt stumbles upon an illegal adoption ring when a woman hires him to find her kidnapped son.
Matt is convinced that the man who kidnapped and tormented a little boy is the same man that kidnapped and tormented him when he was a boy.
A birthday party for Cousin Will turns sour when Matt is informed that he's parked on a roof, ready to jump.
Matt must rescue C.J. and Roy from small town oil embezzlers.
An old college friend asks for Matt's help in solving the murder of his wife, killed hours after their wedding.
Matt meets his female counterpart while investigating the murder of two guests at a resort.
A stewardess accidentally happens upon and photographs a murder and asks Matt to protect her.
One of Roy's former intelligence associates tells him that a Russian agent whom they took down years ago and who swore vengeance is back. It's not long after that that the man is killed. So Roy tries to find the agents who helped him before the man gets them all.
After suffering his umpteenth concussion, Matt falls head over heals in love with an Irish heiress who is being brainwashed by her Irish-terrorist brother.
Matt and company investigate a drug ring.
Houston's about to marry Elizabeth. But when a serial killer who's looking for some notoriety sees that the press is not paying attention to him. He decides to bring Houston into it. And it threatens to jeopardizes his plans with Elizabeth.