Farina and Harry aren't having much luck with their boxing enterprise: Wheezer and Beezer are barely able to attract two spectators. Farina notices that Joe and Chubby are competing for Jean's affection, but that neither of them has the guts to fight. He puts them into the boxing ring, telling each of them that the other has agreed to lay down.
On a particularly windy night, Jackie gets locked out of his house wearing only his nightshirt. He climbs a ladder to Mary Ann's window, but when she realizes his visit isn't of a romantic nature, she kicks him out. Jackie also manages to convince the neighborhood that a burglar is prowling around, giving Kennedy the Cop an excuse to bumble around.
Spud has to stay home and "grease" Wheezer, who has the croup, and can't join the gang on their hunting trip. However, Mary Ann agrees to watch Wheezer if Spud takes them along, so the journey gets underway after all. Some bootleggers are stationed near where the gang has set up camp, and one of them puts on a gorilla costume to scare them.
It's the first day of school, and the gang is lamenting the loss of their beloved Miss McGillicuddy. Their new teacher is Miss Crabtree, and the gang has all kinds of pranks in store for the old battleaxe. Jackie even brags about it to a nice young woman who gives him a ride to school. As it turns out, this nice young woman is Miss Crabtree herself.
Summer is fast approaching, and Jackie is worried that Miss Crabtree will get married and leave her students the way Miss McGillicuddy had the previous year. When the teacher's brother comes around looking for her during her lunch break, the gang thinks he's a prospective husband and schemes to discourage him from pursuing her.
The authorities decide that Stymie belongs in an orphan asylum rather than being cared for by Farina. The older boy throws a going away party for his little brother, but Stymie conveniently forgets to invite the gang, insuring that he can eat all the treats himself. When the official from the orphan asylum arrives, the gang tries to sabotage his plans.
It's time for Grandma to move to the county home. It seems newly-married son-in-law Dan has squandered all her savings and the new wife doesn't want the old woman around. As she's packing her things, she gives Chubby some useless bonds to make a tail for his kite. A letter arrives, which Dan gets his hands on. After "accidentally" breaking Grandma's glasses, he reads the letter to her, stating that the bonds are useless. It turns out that the letter says the opposite, that the bonds are worth plenty of money, but by the time Grandma realizes this, Dan's already chasing down the kite, while the gang chases after him.
The gang is skipping school in order to listen to the rousing stories of the old sea captain. When Miss Crabtree complains, the two of them devise a scheme to scare the kids into giving up their ideas of becoming pirates. The captain arranges for them to arrive that night to start their first voyage, only to become a slave-driver once they're on board.
It's the first day of school, and Brisbane is reminded by his mom that if he does well, he'll grow up to be president. He'd rather be a streetcar conductor, actually. The local blacksmith tells him a story about a boy who got expelled for playing pranks on the teacher, and this suits Brisbane just fine. He proceeds to devise any number of bad deeds, culminating in bringing a mule into the classroom. Sure enough, he's sent away by Miss Crabtree. What he didn't consider was that he'd have to explain all of this to Mom.
The gang attends a lawn party given by a wealthy matron for the benefit of poor children. Also attending are a couple of crooks, one of whom is dressed as a woman, and two midgets posing as their infants. As the party wears on, the midgets steal jewelry from the women who cuddle with them. Meanwhile, Stymie tries to convince the gang that the babies can talk.
The gang is angry with Stymie for stealing a pie, but they forgive him when he frees their dogs from the dogcatcher. When the man hears what Stymie did, he confiscates Pete, and tells Stymie that he'll need five dollars within the next half hour to get the dog back. A convenient wind blows a five dollar bill Stymie's way in answer to his prayer, and a cop chases him around to get it back for the woman who lost it.
The gang starts their own fire department and get right to work on snoring like real firemen. Brisbane spots the local fire brigade answering a call and sounds the alarm for the kiddie version to follow them. They take too long and have no idea where the fire is, but another fire is conveniently burning nearby, so they go to work on that one.
The gang, inspired by the Aladdin story, is busy rubbing every lamp they can get their hands on. A nearby magician overhears their plan and presents himself as the genie of the lamp. Spanky wishes for Cotton to be turned into a monkey, which appears to happen thanks to a vaudeville chimp that happens along.
The boys want to get out of going to school, so Joe and Farina help out by writing phony notes for them. As it turns out, the class is being treated to a day at the local amusement park, and once the boys hear of this, it's too late. They decide to head off for the rides, anyway, but have to contend with a teacher who pretends not to know them, and a truant officer bent on teaching them a lesson.
The kids' Uncle George is in town, having brought with him a wild man from Borneo. Dad doesn't want him near the house, but Mom sends Dickie, Dorothy and Spanky (joined by the gang) to visit him at his sideshow tent. The kids, however, think that the wild man is their Uncle George, and the wild man is basically a grown child who is pacified by candy, which he calls "yum yum eat 'em up." When Stymie pulls out some candy, Bumbo exclaims "Yum yum, eat 'em up!" which sets off a wild chase, as the kids think it's THEM he wants to eat.
It's Spanky's first night in his own room, and he's spooked by every little bump in the night. A burglar introduces himself as Santa Claus and is nice enough to get a glass of water for the boy. When the gang come along to see if Spanky can take Pete for a few days, he points out Santa Claus to them and they sick Pete on the man.
A rich kid moves into the neighborhood, and the gang paws all over his shiny fire engine. When Wally's girl, Jane, takes a ride with the snotty brat, Wally boasts that the gang has their own fire engine. Eventually they do, but they have to build it first. To test their new ride, they race the rich boy down a steep hill.
The local bully lassos Marianne's doll and hurls it into the street, where it gets crushed by a passing vehicle. The gang vows to find her another one before sundown. As it turns out, there's a doll in the window of a nearby store that's just right, but the owner's son is the very same bully. The gang begrudgingly trades in Pete for the doll, but then breaks a vase, and must give back the doll in payment for the damages. Luckily, Pete attacks the owner and his son, and they reluctantly give the doll to the gang in return for taking back their dog.
The boys are getting ready for a camping trip, but can't be bothered to bring along Spanky and Scotty. The little kids decide to go on their own, and manage to get there way ahead of the older boys. They also remember to bring food, which the older boys have forgotten to do. When it gets dark and things get scary, Spanky and Scotty are having the time of their lives.
Wally's over-protective mother goes shopping and leaves the boy in the care of Barclay, the chauffeur. Wally orders him to "drive down some alleys" and comes upon the gang, who are riding on a makeshift merry-go-round powered by their mule, Algebra. To make the mule go, all you have to do is sneeze. To get her to stop, you need to sound an alarm clock. The action is soon relocated to Wally's mansion, where the mule runs rampant every time somebody sneezes, which is often.
The gang arrives at the local radio station to audition for a show featuring child talent. Little did the station manager realize that The International Silver String Submarine Band was merely a bunch of ragamuffin kids with makeshift instruments. The station manager has no luck winning over a visiting prospective sponsor, as most of the "talent" is unimpressive, and the gang is generally disrupting the proceedings. As a last ditch effort, he finally gives the gang their chance to perform, and they win over the sponsor with a rousing performance of "The Man On The Flying Trapeze."
Waldo's "mater" has arranged for him to play violin for the Maids of Olympia, a women's group of which she's hoping to become the president. When he sees the gang's football game outside, he joins in and manages to get mud all over himself. They invade the laundry room, but succeed only in shrinking Waldo's suit down to doll size. To his mother's horror, he arrives at the luncheon wearing a lampshade, and the gang barges in and makes a ruckus of the place.
Spanky's mom forbids him to join the gang in looking for treasure in a nearby cave. He sneaks out anyway, and the gang succeed in finding a giant treasure chest which they break open. After helping themselves to as much loot as they can carry, they try to find their way out. They find themselves in a room with oversized furniture, and soon find out why it's oversized when a giant walks in.
The gang is poorly treated at the orphanage, but today they're being treated to a party at the home of Mr. Wade, a prospective sponsor. His daughter, Mary, and her boyfriend, Dick, come upon a magic lamp that turns them into children, and they join the orphans for ice cream and cake. Unfortunately, when the party ends, the two of them are mistaken for orphans and taken back to the orphanage, where they witness the abuses first-hand.
Spanky has been appointed treasurer of the gang's new club, and as such, keeps their money in an envelope. Meanwhile, his forgetful father needs a reminder from the maid that it's his wedding anniversary, so he places an envelope of money on the kitchen table as a gift for his wife. Unfortunately, his absent-mindedness leads him to then place the envelope in a book he's carrying ("How To Improve Your Memory") and walk out the door. Then Spanky comes in and sets the gang's envelope on the table. When his mom walks into the kitchen, she sees him take the envelope and find a hiding place for it. She goes to her husband's office and reports this incident, and he calls the maid to send Spanky over there right away. This turns out to be impossible, though, since the club has just broken up, and the gang is demanding their money, which is no longer in Spanky's hiding place.
Spanky's mom has aspirations of her son becoming a great actor, so she enters him in a local talent contest. Not wanting an actor's life, Spanky arranges for the gang to sabotage his performance with noise-makers and pea-shooters. At the contest, Spanky meets Marianne, whose mother can't afford to buy her a dress she's been wanting, and wants very badly to win the prize money. This turns out to be impossible, as Marianne is overcome with stage fright, so Spanky decides to win the prize for her. The gang, however, doesn't get the message about his change of plans, and destroys his act, anyway.
It's the last day of school, and the kids are dismayed to find that their beloved Miss Jones will be replaced the following year by a Mrs. Wilson. They soon meet Miss Jones' fiance, Ralph, and give him a cold greeting. At a farewell party that night, they try a number of schemes to convince "that Ralph guy" to dump Miss Jones, not realizing that Ralph's last name is Wilson.
The gang's all set to have themselves a game of football, but Spanky's mom is going out and is leaving Spanky in charge of the baby. The solution: get the baby to fall asleep. Walking her back and forth across the yard only succeeds in tiring out her big brother. So, Spanky and Alfalfa take her upstairs to bed, where Alfalfa sings her a lullaby.
Spanky has a new fishing pole, so there'll be no Sunday school for him today. Buckwheat and Porky tag along as he ventures off for a nice spot to fish. A crabby property owner comes along and shoos them away, however, and they find themselves wandering through the woods. Some black people are holding a baptism ceremony at a nearby river just as a solar eclipse occurs, and the boys get a good scare.
The gang has its collective eye on a $50 prize being given away that day at the local radio amateur contest. They hold auditions among themselves to see who will perform on the show. After turning down Alfalfa several times (he wears several disguises), they overwhelmingly choose Darla, who wows them with her rendition of ""I'm In The Mood For Love."" At the radio station, however, Darla is late, and Alfalfa sings the song in her place.
A mean-spirited store owner prevails upon the local cop to send kindly old Gus and Scotty elsewhere with their lemonade stand. They end up on a little-traveled street where people don't tend to pass. That's until the gang brings a parade through the neighborhood and puts on a show right next to the lemonade stand.
The gang's toy airplane flies into the house of a cranky old rich woman and breaks a vase. To get their airplane back, they must do chores around the yard. It isn't long before they convert the old sourpuss into a best friend, much to the dismay of the butler and the maid, who think she should watch out for her health.
It's Arbor Day, and Spanky has decided to play hooky in order to avoid performing in the pageant the school is giving. Unfortunately, the truant officer sees to it that he makes it to school. Meanwhile, a couple of sideshow midgets have disguised themselves as children in order to sneak out for a little liberty. The truant officer mistakes them for real children and dutifully deposits them in the schoolroom, where they offer to take part in the pageant, performing a racy vaudeville number.
It's the first day of school, and Spanky and Alfalfa have cooked up a scheme to be sent home. Spanky fixes up Alfalfa with a phony toothache by blowing up a balloon in his mouth to create the illusion of swelling. But the new teacher has overheard their scheme. She sends them home, but only after letting them know about the ice cream that's on its way to the classroom. The toothache miraculously disappears, but the balloon gets caught in Alfalfa's throat. The teacher wants him to sing a song, which he does, complete with a high-pitched squeak every time he inhales.
Spanky has a plan to get some firecrackers away from Buckwheat and Porky so that he and Alfalfa can set them off. They disguise themselves as a man (with Spanky on Alfalfa's shoulders) and intimidate the two younger boys. Recess is over before they can light off the firecrackers, so Alfalfa puts them in his back pocket. Inside, he volunteers to recite "The Charge of the Light Brigade." As Porky focuses a magnifying glass on Alfalfa's back pocket, the poem receives some added special effects when the firecrackers go off.
Unable to get the local kids to pay a penny to see the gang's performance of ""Romeo and Juliet,"" Alfalfa gets them in by letting them pay as they exit if they like the show. As the show gets underway, Darla storms out, unable to tolerate Alfalfa's onion breath. After Spanky stalls off the crowd with his ""old act,"" the play continues with Buckwheat in the role of Juliet.
As school lets out, Spanky and Alfalfa send Buckwheat and Porky back into the building to deposit a phony doctor's note on the teacher's desk, so that they can skip school the next day and go to the circus. As the teacher's leaving, she tells the boys that she's taking the whole class to the circus. When they run back to the building to retrieve the notes, the little kids are just closing the doors, which are now locked. They show up that night to break into the school and get the note back. Stormy weather, a power outage, and various other spooky happenings, send all four boys - and the janitor - running for their lives.
There's a new bully in town named Butch, and to save time, he'll just lick the toughest guy in the school rather than the whole class. Through a mishap, Alfalfa finds himself volunteered, but Spanky stalls Butch in order to organize a boxing match. Alfalfa is hopelessly outmatched in the ring, but fortunately, Buckwheat and Porky come to his rescue by conking Butch in the head from behind a curtain.
It's Valentine's Day, and the boys decide they don't want anything to do with it, forming ""The He-Man Woman-Haters' Club."" Almost immediately, Darla passes by and winks at Alfalfa, who drops the club like a hot potato and follows her for a picnic lunch. While Alfalfa pushes Darla on the swing, Spanky and Buckwheat replace the cheese in Alfalfa's sandwich with bar soap, and the cream in the cream puffs with liquid soap. Not wanting to offend Darla, Alfalfa eats all of it. In the classroom, he is summoned to sing a song for the class, which is punctuated with bubbles from Alfalfa's mouth.
Butch and Woim steal Buckwheat and Porky's marbles and smear tomatoes in their faces, so the two younger boys go to Spanky and Alfalfa, who are running a protection agency. After Alfalfa's failed attempt to intimidate the two bullies, Spanky brings in plan two: pelting the bullies with tomatoes. This leads to a chase that ends in the local ballet school. Inside, Spanky and Alfalfa disguise themselves as ballerinas and find themselves in the dance recital. Not to be outdone, Butch and Woim switch clothes with a couple of the boys in the recital and engage in a rough dance sequence with Alfalfa.
The boys overhear the teacher requesting a week-long closure of the school so she can attend her sister's wedding. The superintendent of schools says that nothing short of an epidemic would accomplish that. The boys decide to create an epidemic, and inflate rubber balls under their shirts to give themselves fat stomachs, and paint spots around their eyes. Meanwhile, Waldo finds out that, in light of the students' exemplary grades, the superintendent will make an exception and close the school. He sends Porky to deliver a note to the boys, but Spanky doesn't have the patience to wait for Porky to remember which pocket it's in. The boys go to a doctor to be diagnosed, not realizing he's a veterinary doctor. He examines Buckwheat first, behind a closed door, leaving Spanky and Alfalfa to overhear details about monkey serums and the like. When the doctor leaves, they go in for Buckwheat, only to find a monkey sitting there.
Spanky and Alfalfa are finding themselves with very little free time, as they have to babysit their infant siblings. They decide, with Buckwheat and Porky, to run away. As they arrive in a small town, they notice that the owners of the local bakery are feeding stray dogs. Spanky and Alfalfa ask for some treats for their dog, but only get dog biscuits. Buckwheat and Porky then walk right in with another dog, who turns out to belong to the proprietors. Playing along, the kindly folks give the two boys every treat they request for the dog. As the boys are all eating cake and cream puffs, the proprietors overhear them talking about being runaways. It's decided that the boys must be taught a lesson, so the man dresses as a local sheriff and arrests the boys, putting them in striped prison outfits.
The boys are treating Darla's father to repeated renditions of ""Home, Sweet Home,"" delivered with a liberal dose of cacophony. But it's getting late, and as they open the door to leave, it suddenly starts to rain. Mrs. Hood will sleep with Darla, while the four boys will share Mr. Hood's bed. It doesn't take long for him to leave for the living room couch, where he covers himself with a bearskin rug and dreams of the four boys as miniature devils poking him with pitchforks.
Alfalfa's putting on a William Tell-style performance with his popgun. He uses a mirror to shoot backwards at the apple on Buckwheat's head, only to find that the suction-cup dart has made a direct hit on Butch's nose. When it becomes clear that he's going to get beaten up, Alfalfa faints. This gives Spanky enough time to work up one of his schemes: he takes Alfalfa back to the clubhouse and puts him in bed. The bed has a hole through which Alfalfa can put his lower leg, so that Spanky can fix him up with a fake leg, complete with a misformed foot made out of a fish inside a long sock. The plan works on Butch, who learns that Alfalfa was injured sticking up for his pal, Butch.
The gang has turned their clubhouse into Spanky's Voice Studio, with the singular purpose of furthering Alfalfa's singing career. He's scheduled to perform at a radio contest in which Butch is also a contestant. The bully arrives at the studio to intimidate Spanky into keeping Alfalfa out of the show. Using a frog in a scarf, Spanky convinces Alfalfa that he's lost his voice, so the boys sit in the clubhouse listening to the show on the radio. Finally, Spanky gets a guilty conscience and takes Alfalfa to the station, where he wins the contest, even though his singing is repeatedly punctuated by the sound of a croaking frog.
Alfalfa's in military school, and has been writing home to Darla about his single-handed football victories. The only problem is, he's never played football in his life, and when he arrives home on the train, there's a huge throng of kids to welcome him with cheers. Spanky announces that Alfalfa will be leading the local team to victory in a football game being played that day. After spending half the game avoiding any action on the field, Alfalfa finally has to play, and his bungling actually results in success for his team.
Spanky has called the boys of the neighborhood together for a meeting. Upset that they weren't invited to the MacGillicudy girls' party, he proposes that they form a He-Man Woman Haters' Club and nominates Alfalfa as president. Alfalfa, meanwhile, is not at the clubhouse, but busy writing a love letter to Darla, giving it to Buckwheat and Porky to deliver. When he gets to the clubhouse and learns of his new duties (and of the paddle that will be used on all misbehaving members), he hurries over to Darla's house to retrieve the note. Buckwheat and Porky return, and let the boys know where Alfalfa's gone, so Spanky and the paddle-wielding Spike head over to Darla's. Once there, they can't find Alfalfa, but instead find Darla's cousin Amelia, who is actually Alfalfa. He/she flirts with the boys and finds that they, too, are unwilling to abide by the club's rules.
The gang is staging their annual follies show, but ""king of the crooners"" Alfalfa walks out on stage singing opera. Unwilling to give his fans what they want, he and Porky visit a local opera company, where the impresario jokingly gives Alfalfa a contract effective twenty years later. Alfalfa and Porky arrive back at the barn, where Alfalfa takes a nap. He dreams of becoming an opera star twenty years later, only to be booed on opening night. The impresario still has him under contract, and orders him to sing in the streets. He chances upon Spanky, who's just about to walk into his own nightclub, Club Spanky, and invites Alfalfa in. After watching all of his successful friends put on various performances in the club, Alfalfa decides he'll become a crooner again, only to be interrupted by the impresario. As he begs to be let go, Alfalfa wakes from his dream, and tearing up the contract, returns to the stage to croon again.
There's a new girl named Darla moving into the neighborhood, and her father runs a circus, so the boys pay them a visit, claiming to be animal trainers. Alfalfa gets carried away with his boasting, claiming to have secret powers over bears. Darla's dad gets into a bear costume, and Alfalfa has to nervously train him. It actually works, and the bear begins to obey his commands.
It's Mr. Hood's "natal anniversary," and the wife has fixed a nice dinner for him. Just as he's about to get started, the gang shows up to sing him a happy birthday song and give him gifts (a frog, a duck and a cat). The boys have good intentions, but repeatedly succeed in keeping Mr. Hood from eating.
The gang has its collective eye on a three dollar catcher's mitt, but needs another 20 cents. Luckily, Buckwheat arrives with ten cents which he just got from the tooth fairy. Alfalfa reasons that if the boys had all their teeth pulled, they could make a mint. They arrive at a dentist's office and announce their plans. The dentist takes Alfalfa into the operating room to teach the boys a scary lesson.
Alfalfa is a private eye, and with the help of Buckwheat and Porky, tracks a couple of suspects, Leonard and Junior, who are accused of stealing Darla's box of candy. The two little kids get into the cab of a flatbed truck, so the three sleuths climb in back and hide in a box. Leonard and Junior, however, simply exit the opposite side, unknown to the older boys. It turns out the truck is taking supplies to a haunted house carnival ride, which is where the boys find themselves, but they think their encountering actual spooks.
Spanky has a plan to get out of going to school in the morning. Alfalfa has stayed the night, and they convince Spanky's mom that Alfalfa is very sick, and that Spanky should stay home with him. When she finds out from Buckwheat and Porky that there's some fishing in their plans for the day, she goes shopping, and leaves Junior behind with the older boys. They try in vain to get Buckwheat to watch Junior, but only succeed in losing track of him. He ends up in a weight-reducing cabinet, and by some stroke of sheer idiocy, Spanky and Alfalfa both go in after him and lock the door behind themselves. Junior exits through the hole in top and turns the machine on.