Shane, 12, is recovering from a stroke caused by a freak football accident, while nine-year-old Hannah records her video diary as she receives treatment for juvenile arthritis. Eight-year-old Matthew, who has Duchenne muscular dystrophy, takes part in a medical trial with the aim of improving his symptoms, and is determined to enjoy life to the full.
Keir, 13, has cystic fibrosis but is determined to use his time at Newcastle's Great North Children's Hospital to improve his lungs. His dream is to have a sleepover at his friend's house without his oxygen equipment in tow. Meanwhile, Kirk, also 13, gets behind the camera to show what it's like for a child to have major surgery, and 11-year-old Amy visits for her final dose of chemotherapy.