The Pussycats are in New York City for a recording session. A mix-up in the mail brings them plans for a top secret device that can deactivate the world's technology. The Pussycats' sheet music, meanwhile, ends up in the clutches of a mad criminal called the Laser, who is determined to get his hands on the plans that the gang now have. It is up to the gang to hitchhike to the Laser's hideout in the Grand Canyon and foil his plans.