In conversation and song, Sir Tom Jones shares captivating stories from his career - including his friendship with Elvis Presley.
Brian and Mark visit Mark's own British Grove recording studio to meet fellow Geordie Sam Fender, who discusses his musical journey so far.
Brian and Mark meet 80s icon Cyndi Lauper in New York where she discusses her tumultuous career and teaches them how to play 'True Colours'.
In Miami, disco legend Nile Rodgers explores his impressive musical career, from Studio 54 to David Bowie and Daft Punk.
Brian and Mark visit Carlos Santana, discussing his incredible journey in music from the early days through to his resurgence in the late 90s.
Brian and Mark meet Mark's long-time friend Emmylou Harris, discussing her career highlights before rocking out with guitarist Vince Gill.