Rufus Hound is transported into a parallel universe and has to stop the evil Dr Muhahahaha from sucking every person on Earth down the back of their sofas. Rufus hatches a plan to save the world by knitting the biggest sock in the universe. However, between Dr Mu's Scissor Ships, the fact that no one actually knows where the Space Vacuum is and Doctor Muhahahaha's hand hovering dangerously over the reset button, saving the world is not going to be an easy task.
Rufus faces a familiar-looking enemy as he tries to prevent Dr Mu from taking over the multiverse. All he has to do is negotiate three chambers containing his deepest, darkest fears, battle a giant broccoli monster, defeat his evil clone, destroy Dr Muhahahaha's cloning device and prevent him from hitting his time-reversing reset button. Just another day for the hapless TV presenter.
Everyone on Earth has suddenly developed really bad breath and Dr Mu is, of course, to blame. Rufus is transported to a junk asteroid made entirely from rubbish, the Planet Flotsam, where Dr Mu is extracting the powerful Grot Particle and beaming it across the universe to Earth. Can Rufus stop Dr Mu before the epidemic of eggy breath reaches toxic levels and the whole planet has to be evacuated?
Desperate to impress his arch-enemy and old school friend Dr Wu, Dr Mu decides to steal the sun, using a giant intergalactic space wormhole, a plan that threatens to leave the Earth quite literally out in the cold. Can Rufus save the world from its icy fate? And how on earth is a tin of cat food from his future self ever going to help anybody?
Dr Mu's latest hair-brained plan is to invade the Earth using pizza. Harvesting the cheese mountains, giant tomatoes and olive groves of Princess Gelina's homeworld, Dr Mu has built up the biggest pizza chain in the multiverse. And with his profits he is constructing a giant, pizza-shaped starship called the Death Pizza. Can Rufus escape the clutches of Dr Mu's pizza-troopers, rescue the princess, destroy the Death Pizza and save the Earth? Well, maybe, but only if he can remember the ingredients of a Four Seasons.
In an attempt to conquer the last free planet in the universe by first winning the hearts of its children, Dr Mu turns himself into lovable cartoon character, with disastrous consequences for the inhabitants of planet Earth. To defeat the evil Doctor, Rufus must travel to the cartoon world and become an animated character himself.
Dr Mu is stealing the internet! With IT systems in meltdown all over the world, Rufus is transported to the doctor's evil HQ, Mu Force One, where he is captured by Dr Muhahahaha and hurled into the internet. In a social networking site called Puffin Portal, he teams up with two fluffy avatars, Buck and Gelina, and together they set out to foil the evil Doctor's plans and restore the internet from its backup server.
Confusion reigns on Earth as Queen Gertrude of Genovia sacks her cabinet, invites all the world's leaders to attend a conference at her palace and starts behaving very strangely. It soon emerges that Dr Mu has shrunk himself down to the size of a single bacterium, transported himself into her body and is now controlling her! When Rufus decides to go after him, teaming up with a pair of royal brain cells, things don't go quite according to plan.
Dr Mu has invented a highly dangerous robot/toaster and soon mass-produces a robot/toaster army with which to subjugate the Earth. Can Rufus and the cloned workforce of Dr Mu's factory planet prevent the invasion? And will anyone spot the fatal flaw in Dr Mu's scheme? And will Steve be able to get a word in edgeways?
Rufus is transported to the Dream Station, a giant space station in orbit above the Land of Nod, the place where all the dreams in the universe take place. Dr Muhahahaha has sabotaged the Dream Station and is gradually sending the Earth's population to sleep. To save the world from this waking nightmare, Rufus must travel to the Dream Station and find a way to wake the world.
Dr Mu is launching a new evil product called the Mu Box, a games console that turns its unsuspecting customers into zombie-like creatures with TVs for heads. His plan is to create a terrifying Tellyhead army to conquer the world. To advertise his creation, Dr Mu has enslaved Buck Fastness and Gelina Norglobb, the two biggest filmstars in the multiverse, shrinking them down inside a special TV set from which they are forced to broadcast his commercial. Rufus sets out to navigate the airwaves, defeat the Tellyheads, rescue Buck and Gelina and tell the world the truth about the Mu Box.
Rufus finds himself forced to take part in Dr Mu's malevolent gameshow, Cash or Kick Yourself, which he is broadcasting to every civilised planet in the multiverse. To save the world, Rufus must successfully complete every round of the show, evade the show's dubious mascot, Mr Blinko, and win the mystery prize.
The world's superheroes have gone missing! As Earth is gripped by chaos, crime waves and cats stuck up trees, Rufus reluctantly pulls on a pair of extremely suspect underpants - courtesy of his Future Self - and heads to the Planet Invincible to save the day.