First through the doors are Liz and Darren, parents of three from Cambridge. Liz has been severely underweight all her life and it's beginning to take its toll on her self-esteem. Kailey and Dan are next in, a young couple from who are desperate to overcome their fertility issues. Kailey worries on a daily basis about not being able to conceive and it's beginning to have an effect on the couple's relationship and sex life. Kate and her partner Nick from Warrington are next through the clinic doors. Kate suffers from Tourette's syndrome and is looking for help with her tics, which are relentless. Last, but not least, is 74-year-old Frank who has varicose veins. Not only is his condition causing him great discomfort, but he also finds them embarrassing.