In a distant galaxy, a Princess named Angelica and her friend Professor T. Bird are under attack from an evil Queen and her Beast Police. They flee to a remote planet where they gather the genetic essence of the Battletoads in order to create a new generation of warriors. They head to Earth in an attempt to find three humans that are worthy of protecting the Princess and the magical amulet she wears. At that very moment, three nerdy teenagers are being scolded by their principal, then told to avoid each other while in class. After school they meet at the arcade, where T. Bird and Princess Angelica suddenly appear and offer the three boys a chance to become Royal Guards for the Princess.