Comedy legend George Lopez brings out his new rescue dog, "Dr. Ken's" Suzy Nakamura plays "Name That Sound" and trainer Terry Simons helps some dogs and Anthony himself run an agility course live on stage.
Jerry and Anthony hatch a "Kangaroo Jack" reunion. "The Real" host Loni Love brings pictures of her unique animal hat. A hawk takes its time deciding what to do on Anthony's arm.
"Scandal" actress Bellamy Young takes an animal pop quiz. Comedian Steve Byrne gets jealous of his cat. Jules Sylvester lets a rattlesnake loose live on stage.
Cheryl Hines shares photos of her pet emu. Dan Cummins recalls how rural kids get pets. Jeff Musial shows off a zebra and a camel.
"Casual" Actress Michaela Watkins gives animals new names. Comedian Nicole Sullivan tells cat tales. Anthony voluntarily gets attacked by a trained security dog.
"Justified" actor Walton Goggins describes animals under the sea and scuba diving with his wife. "Two Broke Girls" actor Jonathan Kite impersonates a cat and a celebrity at the same time. Dave Salmoni shows Anthony an alligator.
"Fear The Walking Dead" actress Mercedes Mason argues about turtles. Joey Diaz showers with a cat. Mutual of Omaha's Stephanie Arne pushes the cute meter with baby otters AND a sloth.
"Lethal Weapon" actress Keesha Sharp plays "Avoid, Adopt, Eat" with Anthony. Fred Willard encounters a skunk. Cat expert Jackson Galaxy answers pressing feline questions from the audience.
"Lady Dynamite" star Maria Bamford debuts her new dog. Jen Kirkman describes how a goat kick feels. Animal expert Dave Salmoni shows off a bearcat and a porcupine.