| Name | Type | Role | |
|---|---|---|---|
| Park Woo-jin | Musical Guest | Wanna One - Woojin | |
| Yoo Ki-hyun | Musical Guest | Monsta X - Kihyun | |
| Lee Know | Musical Guest | Stray Kids - Lee Know | |
| Jin | Musical Guest | BTS - Jin | |
| Kim Jae-hwan | Musical Guest | Wanna One - Jaehwan | |
| Stray Kids | Musical Guest | "Overdose" + "Growl" (orig. by Exo), "P.A.C.E", "Hellevator", "District 9" | |
| Hwasa | Musical Guest | Mamamoo - Hwasa | |
| Felix | Musical Guest | Stray Kids - Felix | |
| Myoui Mina | Musical Guest | Twice - Mina | |
| V | Musical Guest | BTS - V | |
| Lee Dae-hwi | Musical Guest | Wanna One - Daehwi | |
| Chae Hyung-won | Musical Guest | Monsta X - Hyungwon | |
| Seungmin | Musical Guest | Stray Kids - Seungmin | |
| RM | Musical Guest | BTS - RM | |
| Lai Guanlin | Musical Guest | Wanna One - Kuanlin | |
| Yoon Ji-sung | Musical Guest | Wanna One - Jisung | |
| MAMAMOO | Musical Guest | "Eyes, Nose, Lips" (orig. by Taeyang), "Cleopatra" (Solar), "Easy" (Wheein), "Selfish" (Moonbyul ft. Chaewon), "Don't" (Hwasa), "Egotistic", "Starry Night" | |
| Son Hyun-woo | Musical Guest | Monsta X - Shownu | |
| Kim Yu-gyeom | Musical Guest | Got7 - Yugyeom | |
| Han | Musical Guest | Stray Kids - Han | |
| Jimin | Musical Guest | BTS - Jimin | |
| Lee Joo-heon | Musical Guest | Monsta X - Joohoney | |
| Park Ji-hoon | Musical Guest | Wanna One - Jihoon | |
| Solar | Musical Guest | Mamamoo - Solar | |
| Hwang Min-hyun | Musical Guest | Wanna One - Minhyun | |
| Im Na-yeon | Musical Guest | Twice - Nayeon | |
| Monsta X | Musical Guest | "Spark" (Jooheon), "Jealousy", "Shoot Out" | |
| Ha Sung-woon | Musical Guest | Wanna One - Sungwoon | |
| Shin Ho-seok | Musical Guest | Monsta X - Wonho | |
| Bae Jin-young | Musical Guest | Got7 - Jinyoung | |
| Hyunjin | Musical Guest | Stray Kids - Hyunjin | |
| j-hope | Musical Guest | BTS - J-hope | |
| Kang Daniel | Musical Guest | Wanna One - Daniel | |
| Im Chang-kyun | Musical Guest | Monsta X - I.M | |
| Moon Byul | Musical Guest | Mamamoo - Moonbyul | |
| Bang Chan | Musical Guest | Stray Kids - Bang Chan | |
| Hirai Momo | Musical Guest | Twice - Momo | |
| BTS | Musical Guest | "Fake Love", "Anpanman" | |
| Bae Jin-young | Musical Guest | Wanna One - Jinyoung | |
| Lee Min-hyuk | Musical Guest | Monsta X - Minhyuk | |
| I.N | Musical Guest | Stray Kids - I.N | |
| Lim Jae-beom | Musical Guest | Got7 - JAY B | |
| SUGA | Musical Guest | BTS - Suga | |
| Ong Seong-wu | Musical Guest | Wanna One - Seongwu | |
| Wanna One | Musical Guest | "Light", "Boomerang", "I.P.U [I Promise You]", "Heartbeat" (orig. by 2PM) | |
| Jung Whee-in | Musical Guest | Mamamoo - Wheein | |
| Changbin | Musical Guest | Stray Kids - Changbin | |
| Minatozaki Sana | Musical Guest | Twice - Sana | |
| Jung Kook | Musical Guest | BTS - Jungkook | |
| Park Bo-gum | Host | Main host & presenter for "Birth of a Hero" performance | |
| Shin Ah-young | Guest Star | Presenter for Favorite Vocal Artist | |
| Choi Kang-hee | Guest Star | Presenter for Favorite Female Dance Artist and Worldwide Fans Choice Award | |
| Kwon Hyuk-soo | Guest Star | Reading famous tweets and presenter for "Crime And Punishment" Performance and Worldwide Fans Choice | |
| Yang Se-jong | Guest Star | Presenter for Favorite Male Dance Artist | |
| Jang Hyuk | Guest Star | Presenter for Worldwide Icon of the Year (Daesang) | |
| Choi Tae-joon | Guest Star | Presenter for Worldwide Fan Choice Award | |
| Jung Il-woo | Guest Star | Presenter for Worldwide Fans Choice Award | |
| Yoon Hyun-min | Guest Star | Presenter for Worldwide Fan Choice Award | |
| Lee Sung-kyoung | Guest Star | Presenter for Worldwide Fan Choice Award | |
| Jung So-min | Guest Star | Presenter for Worldwide Fans Choice Award | |
| Lee Da-hee | Guest Star | Presenter for Worldwide Fan Choice Award | |
| Yutaka Matsushige | Guest Star | Presenter for Favorite Vocal Artist | |
| Ha Seok-jin | Guest Star | Presenter for Favorite Music Video, Favorite Female Dance Artist and Worldwide Fans Choice Award | |
| No Min-woo | Guest Star | Presenter for Favorite Dance Artist (Japan) |