Series following the work of the specialist vets, staff and animals at a 24/7 pet hospital in County Durham.
Six-year-old Labrador Nugget is referred to the hospital by his local vet when they find a mass on his right kidney. He needs specialist tests. Walter, his 87-year-old owner, took on Nugget when his previous owner, Walter's daughter, died. Walter is worried that it could be cancer, and he may lose him too.
The critical care team work to save the life of a tawny owl that has been found badly injured on the roadside and brought in by a passing motorist. He's cold and frightened, and his body is starting to shut down. Although the team are more used to treating animals with four legs, they pull out all the stops to try to save him.
A French bulldog called Appona is rushed in by her owner after struggling all night to give birth. She is carrying five puppies, but after doing an x-ray, the team are concerned that the puppies' size may cause complications for mum. Just as they're about to go into theatre to perform a caesarean section, a call comes through from ICU with a surprising development.
Black labrador Bilko is referred to the hospital as he's had an extreme allergic reaction. Despite treatment by his vet, he appears to be getting worse. Initially stable overnight, he takes a turn for the worse, and his heart rate means staff must monitor him closely. Attempts to anaesthetise Bilko for a scan cause further concern, and the team call in cardiologist Brian to treat him urgently.
In this episode, we follow the night-shift team as they treat numerous emergencies, including a cockapoo called Milo, who has been brought in after being sick for an hour, and a six-year-old ferret named after a pop star, who is bloated and not his usual self. It's former veterinary intern Iason's first night in his new out-of-hours role, and he's got 40 furry patients to look after with the team. On his next night shift, a dog is rushed in by her owner after collapsing, and the emergencies continue into the next day, when a St Bernard cross called Wolfie breaks his leg on a walk. Rubble the greyhound is in to give blood, and his fifteenth donation means he's helped save the lives of around 60 other pets.
A Pomeranian puppy called Bear has had an accident and caught her leg in a conservatory door. She sees surgeon Laura, who fits a tiny metal plate to fix her broken bones. It's not always easy treating dogs as small as Bear, but the team adapt. Meanwhile, a cat named Esme is brought in by her owner Kirsty as she has stopped eating and is being sick. As Esme arrives in the consulting room, the team take one look at her and rush her into ICU as they're concerned about her breathing. Colin, a basset hound, arrives for his check-up, supported by his sister Dolly. He has been suffering bouts of pneumonia, so his owner Andrew hopes the medication has helped and he'll get the all-clear.
A dalmatian puppy called Reg is rushed into the hospital after eating a mystery object that's become stuck in his intestines. A scan shows that there's only one way to get it out, and that's to operate. Rupert, a King Charles spaniel, has an appointment to see the experts in the neurology department to try to get to the bottom of his headaches, which can be common in this breed. Becky, his foster carer, would also like to find out what she can do to cure his life-threatening lung infections, and so clinical director Ben looks into his case. In the oncology department, the team are seeing Alexandria, a cat who is undergoing chemotherapy. They hope this will be her last chemo round and give her some well-deserved treats.
Puppy Coal from the Dogs Trust is being treated for aspiration pneumonia, caused by food going into his lungs. He was born at the hospital on Boxing Day by caesarean section, so the team have developed a close bond with him. However, over the last six months, he has suffered repeated infections. After numerous admissions, the team decide to operate to give him the best chance of a normal life. Also in the pet hospital for an operation is Grayson, a border collie puppy who has broken his leg after falling off a bed. With the break near his growth plate, it's vital to get it right. In oncology, a new scanning technique is being used for the first time to check if Poppy the labradoodle has the all-clear from cancer.
Labrador Jasper is brought into the hospital by his owners after struggling to breathe when out for a walk. His tongue is swollen, and it's blocking his airway, so he is prioritised for immediate treatment. Bobby the spaniel has arrived with his owner to have tests to find out why he's suffering from ongoing symptoms, such as sneezing and shaking his head. They hope it's not cancer. Meanwhile, Skye the Bernese mountain dog is treated by orthopaedic surgeon Magic for joint problems, which can be common in large breeds.