Hey... where's Perry? Phineas Flynn and his stepbrother Ferb Fletcher spend their summer vacation embarking on grand new projects (to the chagrin of their controlling older sister, Candace), while the boys' pet, Perry the Platypus, works as a spy to defeat the latest scheme of mad scientist Dr. Heinz Doofenshmirtz.
Each day, two kind-hearted suburban stepbrothers on summer vacation embark on some grand new project, which annoys their controlling sister, Candace, who tries to bust them. Meanwhile, their pet platypus plots against evil Dr. Doofenshmirtz.
Genial stepbrothers Phineas Flynn and Ferb Fletcher will host their own animated/live action talk show, originating from a Danville set complete with a fake skyline, comfy guest chairs and the boys' longtime friend, Isabella Shapiro-Garcia, as the stage manager.
To celebrate the anniversary of Perry becoming their pet, Phineas and Ferb create an enormous shuttlecock to play giant badminton. When Perry's hovercraft accidentally collides with their shuttlecock, the boys crash into Dr. Doofenshmirtz's lab and destroy his "Other-Dimension-inator", which creates portals to parallel dimensions. Intrigued, the two help Doofenshmirtz rebuild the machine. Perry arrives to stop Doofenshmirtz, but unwilling to reveal his secret identity to the boys, reverts to pet mode and is unable to stop them from helping Doofenshmirtz.
Phineas and Ferb set out across the galaxy to rescue their sister Candace, who has been abducted by aliens and has found utopia in a far-off planet, free of pesky little brothers.