Children Lindsey and Kevin Kingston sabotage the relationships of their divorced mother, determined to keep her single until their parents reconcile. Nick Persons, a businessman who hates children, purchases a brand-new 2005 Lincoln Navigator and boasts with his beloved bobble-head of Satchel Paige, who comes to life at its own will – though only Nick can hear him. When he reaches his shop, he witnesses the woman of his dreams, Suzanne Kingston. On his way to talk to her, he is disgusted to find she has two kids, who turn out to be Lindsey and Kevin.
Following the events of ''Are We There Yet? (film)'', Nick Persons (Ice Cube) has married Suzanne (Nia Long) and moved her, Kevin (Philip Daniel Bolden), and Lindsey (Aleisha Allen) into his apartment, also purchasing a 2007 Cadillac Escalade (after he accidentally blew up his Lincoln Navigator SUV in the previous film by leaving the lighter unattended inside). He has also sold his sports memorabilia store to his best friend, Marty (played by Jay Mohr in the first film). The family has also got a Berger Picard and named it Coco. While getting ready for an interview with Magic Johnson to launch a sports magazine, Suzanne tells Nick that she is pregnant and they later find out that there will be twins.