The X-Men are reunited following the death of a teammate, and are summoned by Charles Xavier to Japan following the abduction of Hisako Ichiki (Armor). There, they confront the U-Men, a lunatic cult that steals and transplants mutant organs to further strengthen their own army, and the battle for justice is on.
Tony Stark, CEO of a large weapons manufacturer, physicist, engineer, and brilliant inventor, is wounded by shrapnel from one of his own weapons. While held captive by terrorists, he develops the Iron Man Suit and escapes. From that day on, he vows not to waste his second chance at life and to change the world for the better. For that purpose, he comes to Japan. In Lab 23 in Japan, great strides have been taken to develop, and build, a unique power station which does not run on fossil fuels, the Arc Station. Stark intends to join this project, and, for that, he is ready to announce his retirement as Iron Man. At the same time, he will also announce the Mass-produced Iron Men, to which he will pass on his duties. However, during the ceremonies, Stark is suddenly attacked by combat mecha belonging to an organization known as Zodiac.
Logan learns that his girlfriend, Mariko Yashida, who disappeared a year ago, has been taken to Tokyo by her father Shingen, who is the head of a Japanese crime syndicate and a supplier of AIM.
The story revolves around Blade, a "Daywalker" vampire hunter who was born with vampire and human blood after a vampire attacked his mother. While visiting Japan on a mission, Blade tracks down Deacon Frost, the vampire who killed his mother. Blade confronts "Existence," a mysterious organization composed of vampires modified by Frost.