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Enchanted

2007
as Robert Philip

Grey's Anatomy

2005
as Derek Shepherd

Valentine's Day

2010
as Dr. Harrison Copeland

Bridget Jones's Baby

2016
as Jack Qwant

Disenchanted

2022
as Robert Philip

Scream 3

2000
as Mark Kincaid

Freedom Writers

2007
as Scott Casey

Thanksgiving

2023
as Sheriff Eric Newlon

Devils

2020
as Dominic Morgan

Ferrari

2023
as Piero Taruffi

Made of Honor

2008
as Thomas 'Tom' Bailey

Can't Buy Me Love

1987
as Ronald Miller

Brother Bear 2

2006
as Kenai (voice)

Sweet Home Alabama

2002
as Andrew Hennings

Outbreak

1995
as Jimbo Scott

Coupe de Ville

1990
as Robert 'Bobby' Libner

Jeremiah

1998
as Jeremiah

Ushi Must Marry

2013
as Himself

Some Girls

1988
as Michael

Heaven Help Us

1985
as Corbet

Happy Together

1989
as Chris Wooden

Lucky 7

2003
as Peter Connor

Me and Will

1999
as Fast Eddie

Run

1991
as Charlie Farrow

Bloodknot

1995
as Tom / Son

Flypaper

2011
as Tripp

Face The Music

1993
as Charlie Hunter

The Escape

1998
as Clayton

Loverboy

1989
as Randy Bodek

Scream 7

2026
as Mark Kincaid

Blonde

2001
as Cass

Mobsters

1991
as Meyer Lansky

Crime and Punishment

1998
as Rodya Raskolnikov

Hugo Pool

1997
as Floyd Gaylen

Iron Jawed Angels

2004
as Ben Weissman

A Fighting Choice

1986
as Kellin Taylor

In the Mood

1987
as Ellsworth 'Sonny' Wisecarver

With Honors

1994
as Everett Calloway

For Better and for Worse

1993
as Robert Faldo

Bank Robber

1993
as Billy

In a Shallow Grave

1988
as Potter Daventry

Denial

1998
as Sam

Dexter: Original Sin

2024
as Aaron Spencer

The Treat

1998
as Mike

Boys of Bonneville

2011
as Narrator

Director

Movie Ava's Magical Adventure 1998

Producer

Movie The Art of Racing in the Rain 2019
Movie Flypaper 2011

Guest Star

Episode Will & Grace
Love Plus One
2000
Episode Late Show with David Letterman
Show #2621
2006
Episode Jimmy Kimmel Live!
Patrick Dempsey; Elisabeth Moss; Seth Sentry
2013
Episode The Late Late Show with James Corden
Jimmy Kimmel, Patrick Dempsey, Renee Zellweger, CL
2016
Episode The Daily Show
Patrick Dempsey
2002
Episode Jimmy Kimmel Live!
After The Academy Awards (2010)
2010
Episode The Super Mario Bros. Super Show!
The Pied Koopa
1989
Episode Once And Again
Aaron's List of Dreams
2002
Episode The Jonathan Ross Show
Renee Zellweger, Patrick Dempsey, John Malkovich, the Team GB women's hockey team, Laura Trott and Jason Kenny, Aisling Bea and Tom Odell
2016
Episode Will & Grace
Crazy in Love
2001
Episode Will & Grace
Brothers, A Love Story
2001
Episode Today
June 29, 2011
2011
Episode SurrealEstate
The Harvey
2021
Episode Extra
Patrick Dempsy
2005
Episode The Practice
Pre-Trial Blues (2)
2004
Episode LIVE with Kelly and Mark
Chris Harrison, Patrick Dempsey, Sophia Loren
2016
Episode The Tonight Show with Jay Leno
Patrick Dempsey, Mindy Kaling, Train
2010
Episode Grey's Anatomy
My Happy Ending
2020
Episode Late Show with David Letterman
Patrick Dempsey; Amy Sedaris; Laura Marling
2013
Episode The Oprah Winfrey Show
The Best Burger in America Discovered!
2006
Episode The Practice
Mr. Shore Goes to Town (3)
2004
Episode The Ellen DeGeneres Show
Patrick Dempsey
2011
Episode Once And Again
Feast or Famine
2000
Episode Once And Again
Aaron's Gettin' Better
2001
Episode The Super Mario Bros. Super Show!
Super Plant (The Pied Koopa)
1989
Episode Late Night With David Letterman
Show #1544
1991
Episode Top Gear
Episode 6
2016
Episode Once And Again
Strangers and Brothers
2000
Episode The Project (2009)
Monday 22 Aug
2016
Episode The Tony Danza Show
Episode 130
2005
Episode Late Show with David Letterman
Patrick Dempsey, Erica Hill, Marty Stuart
2011
Episode Private Practice
Ex-Life
2009
Episode Jimmy Kimmel Live!
Patrick Dempsey, Justin Schmidt, Tame Impala
2016
Episode Extreme Makeover: Home Edition
Marshall Family
2009
Episode Jimmy Kimmel Live!
Anthony Davis, Patrick Dempsey, Clare Crawley, OneRepublic
2020
Episode House Party
Puntata 1
2016
Episode Jimmy Kimmel Live!
Sir Paul McCartney; Patrick Dempsey
2013